Senior AI/ML Engineer (RNA biotech) At London Biotech Startup

Posted on August 9,

Summary

  • Challenge: use machine learning to engineer a radically differentiated approach to RNA delivery — one of the biggest bottlenecks in RNA therapeutics
  • Required: An entrepreneurial self starter with experience in AI/ML and mathematics
  • Location: London, UK (possibility to WFH)
  • Start-date: ASAP, 2021
  • Type: Full Time/Permanent

Apply here: https://jobs.lever.co/SixfoldBioscience/a99d7a70-f799-4352-bcf2-80cb7d75710b

The opportunity

Sixfold Bioscience is a VC backed team of 20 researchers and operators looking to change how we treat disease.  We see the huge potential of RNA therapeutics being limited by how safely and effectively it can be systemically delivered in people.

As one of the founding members of our computational team, you’ll be applying your experience in AI/ML and mathematics to develop a computational infrastructure in several areas, including in silico to in vivo prediction, for the development of RNA therapeutics, as well as identify and assist in the hiring of our expanding computational team.

This is an extremely exciting opportunity to join us as we enter a promising phase of team and R&D expansion. You’ll join a highly collaborative, multi-disciplinary and dynamic team environment: a passionate group of coders, chemists, biochemists and biologists looking to make a difference (and have fun doing it!).  You’ll be exposed to advanced research in the rapidly growing field of RNA therapeutics. 

During your time with us, you’ll

Be driving the development of our technology by:

  • Building out our computational team and infrastructure
  • Designing and implementing machine learning models to optimise the speed and efficacy of therapeutic RNA development
  • Working in collaboration with chemists, biochemists and biologists to predict clinical outcomes
  • Devise and conduct experiments to investigate and validate therapeutic molecules from established and novel data sets
  • Develop and apply novel statistical, bioinformatics, and data mining algorithms

You’ll also:

  • Be regularly involved in discussions with the executive team, senior management and the implementation of any actions arising
  • Supervise, train and hire junior researchers
  • Work in a highly collaborative team environment
  • Be involved in Sixfolds many grant projects with leading industrial and academic institutions, such as Imperial College, Pharmidex, Medicines Discovery Captapult and the National Physical Laboratory.
  • Support and contribute to publishing, patenting and grant writing efforts
  • Engage in discussion and activities to take Sixfold to the next growth stage

Who you are

You’ll need extensive experience in machine learning and mathematics. We are not looking for the finished article, you can be fresh out of grad school or an industry vet, what we want to see are the raw ingredients that will allow you to hit what we expect from a senior member of our team, then go beyond that. We look for people who are highly motivated and independent individuals, infinite learners, who are comfortable working collaboratively as part of a multidisciplinary team.

Specifically, you should be someone who:

  • Has a deep understanding of ML/AI
  • Fluent in Python
  • A degree in Computer Science, Mathematics, Bioinformatics, Physics and/or Computational chemistry

Our team is what makes Sixfold. We look for people with:

  • Good humour, friendly and plenty of energy
  • A passion for science and learning
  • Team oriented
  • The ability to work under pressure and prioritise workload

Not required, but helpful

None of the below are required, especially if you are highly experienced in other areas, but any one of the following could add a little stardust to your application:

  • PhD in computer science, mathematics, physics or equivalent
  • Previous research experience in nucleic acids, computational biology, and/or chemistry.
  • Experience designing computational algorithms in additional programming languages, such as: C++, C#, R, Scala, or Julia.
  • Proficiency in the following software packages:
    • Data manipulation (e.g., NumPy, SciPy, pandas).
    • Machine learning (e.g., PyTorch, scikit-learn, TensorFlow, Keras, Docker)
  • Experience working with version control systems (e.g. Github)
  • Experience working in cloud environments, such as Amazon Web Services (AWS)
  • Share Scheme
  • Competitive salary
  • Pension
  • Flexible hours with opportunity to WFH
  • Highly collaborative, inclusive and friendly team environment
  • The chance to see your ideas make an impact
  • Regular team social events
  • Minimum 5 days paid training
  • 25 days paid holiday (not including bank holidays)
  • Cycle to work scheme
  • Free fruit
  • Sickness and bereavement pay
  • Attractive maternity & paternity pay policy

Perks

  • Share Scheme
  • Competitive salary
  • Pension
  • Flexible hours with opportunity to WFH
  • Highly collaborative, inclusive and friendly team environment
  • The chance to see your ideas make an impact
  • Regular team social events
  • Minimum 5 days paid training
  • 25 days paid holiday (not including bank holidays)
  • Cycle to work scheme
  • Free fruit
  • Sickness and bereavement pay
  • Attractive maternity & paternity pay policy

About us

We founded Sixfold to tackle the biggest challenge in healthcare: how to safely deliver RNA to diseased cells. We saw the huge potential of RNA therapies being limited to how safely and effectively they can be systemically delivered in people.  Our scientists are creative and iterate fast because they want to see what they do in the lab make a difference in the clinic.

Diversity and inclusion

It’s important to mention that although disease affects us all, our industry still displays a huge lack of diversity — this needs to change. Our team is composed of many different nationalities, cultures and genders. Our goal is to create a company culture that promotes ideas and the inclusion of team members from all backgrounds.

That means we have no judgement when it comes to any one of the things that make you who you are — your gender, race, sexuality, religion or your secret aversion to cucumber water.

The proof in the pudding: our board is 66% female, and at last count team Sixfold came from 9 nationalities, 3 continents, multiple races and ethnicities. As one of our team recently put it: “Sixfold is a great example of diversity [...] and I am sure many more diversities that I am not even aware of! The beauty of the fold-diversity ”

We actively encourage members of disadvantaged, minority and underrepresented groups to apply.

Further Info/ Apply

Should you have any questions, please email careers[@]sixfold.bio
Apply here: https://jobs.lever.co/SixfoldBioscience/a99d7a70-f799-4352-bcf2-80cb7d75710b
Visit our website: https://www.sixfold.bio/