Postdoctoral Scientist Position in the Brito Querido Lab

Posted on October 31,

We are seeking a Postdoctoral Scientist to work within the group of Dr. Jay Brito Querido in the Department of Biological Chemistry at the University of Michigan Medical School.

The lab is using cryo-electron microscopy and biochemical approaches to study the role of a conserved family of enzymes called DEAD-box (DDX) RNA helicases in the regulation of mRNA translation in humans. The goal is to understand the mechanism underlying translational regulation by these RNA helicases, which should provide insights into processes controlled by translational regulation, including brain development.

Responsibilities

The primary responsibility is to conduct research to advance the understanding of the role of RNA helicases in the regulation of mRNA translation. The successful candidate will develop and apply different techniques, including single-particle cryo-electron microscopy, to study translational regulation. This position will have access to state-of-the-art facilities at the Life Sciences Institute and in the Department of Biological Chemistry.

In addition, this position will contribute to laboratory seminars and discussions, allowing the candidate to impact the direction of their research project and other projects within the research group. Assist in training lab members. Contribute to preparing research for publication and ensure that the research is performed according to best practices – in compliance with the University of Michigan and funding agency's guidelines.

Required Qualifications

PhD in biological sciences or related field with at least 2-3 years of laboratory research experience. The ability to work productively in a team environment with people from diverse backgrounds, work with limited supervision to identify a broad range of techniques to achieve the project's primary goal. The successful candidate will be highly motivated, able to multi-task efficiently, work independently and be committed to research. Some evening and weekend work may be required. 

Desired Qualifications
Experience in RNA biology, helicases, structural biology, and neurology is an advantage. 

To apply: https://careers.umich.edu/job_detail/225589/research-fellow