Postdoctoral ResearcherFebruary 8, 2023 University of Sheffield - Faculty of Science - School of Biosciences Are you interested in working as part of a large collaborative team that will employ an innovative multidisciplinary strategy to dissect the molecular mechanisms of ribosome specialisation? A postdoctoral Research Associate position is available in the research group of Dr Emma Thomson at the University of Sheffield. The Research Associate will be part of a large collaborative team between the Universities of Sheffield, Leeds and Nottingham, funded by a BBSRC Strategic Longer and Larger grant (sLoLa) led by Dr Julie Aspden. This project aims to unravel how compositionally distinct ribosomes enable translation of specific mRNAs across different eukaryotic model systems that cover >1 billion years of evolution. Overall, we aim to understand the detailed molecular mechanisms of ribosome specialisation and determine common features across eukaryotes. As a Research Associate you will investigate the function and mechanism of specialised ribosomes through a combination of genome engineering, affinity purification of specialised ribosomes, selective RiboSeq and translational reporter assays. We’re looking for someone who has or is close to obtaining a PhD (or equivalent) with a focus on gene expression, translation, RNA biology or similar discipline; a track record of research and publishing in Protein translation, gene expression, RNA biology or similar discipline; and expertise in molecular biology methodologies including cloning, RNA and protein analyses, and qPCR. We’re one of the best not-for-profit organisations to work for in the UK. The University’s Total Reward Package includes a competitive salary, a generous Pension Scheme and annual leave entitlement, as well as access to a range of learning and development courses to support your personal and professional development. We build teams of people from different heritages and lifestyles from across the world, whose talent and contributions complement each other to greatest effect. We believe diversity in all its forms delivers greater impact through research, teaching and student experience. To find out what makes the University of Sheffield a remarkable place to work, watch this short film: www.youtube.com/watch?v=7LblLk18zmo, and follow @sheffielduni and @ShefUniJobs on Twitter for more information. To explore the post further or for any queries you may have, please contact: Dr Emma Thomson ([email protected]) Dr Julie Aspden ([email protected]) |