Postdoctoral Positions to Study Biology of Stress Granules and tRNA-derived stress-induced RNAs

Posted on September 8,

Two postdoctoral positions are available to study RNA-mediated stress responses, biology of tRNA-derived RNAs and RNA Granules. We are seeking to recruit two new colleagues that will have joint appointment in the laboratories of Paul Anderson and Pavel Ivanov at the Brigham and Women's Hospital and Harvard Medical School, Boston, USA. Positions are available immediately and supported by recently obtained NIH grants. Initial appoitments will be made for three years with the possibility of extension.

Our laboratories work at the cutting-edge of RNA biology and cell biology. We focus on two major overlapping topics. The first is investigating stress-induced adaptation of mRNA translation and functions of novel non-coding RNAs derived from tRNAs (so called stress-induced tRNA-derived RNAs, or tiRNAs) (see Yamasaki et al. J Cell Biol 2009; Ivanov et al. Mol Cell 2011; Ivanov et al. PNAS 2014; Lyons et al. NAR 2016; Lyons et al. Nature Communications 2017; Lyons et al. NAR 2020; Akiyama Y et al. RNA Biology 2020, Akiyama Y et al. RNA Biology 2021). The second is investigating Stress Granules, RNA granules with multiple functions in cellular physiology and pathophysiology (Kedersha et al. J Cell Biol 2016; Fay et al. Cell Reports 2017; Panas et al. J Cell Biol 2016; Aulas et al. J Cell Science 2016; Panas et al JCB 2019) . We employ diverse  RNA-based tools to illuminate the biological and biomedical significance of tiRNAs and Stress Granules.

Candidate requirements: A PhD degree (or equivalent) in the biological sciences or a closely related field. Previous experience in molecular and cell biology is necessary. Prior knowledge of basic RNA biology methodology is desired. Evidence of scholarly ability (record of publication in peer-reviewed journals, conference presentations, etc). The candidate is expected to have adequate writing skills, prepare and write research papers, conference presentations and research proposals. Two major requirements include the ability to work independently as well as in the team and a high level of motivation. 

It is expected that high quality publications will result from this work.

Brigham and Women's Hospital and Harvard Medical School  are  equal opportunity employers. All qualified applicants will receive consideration for employment without regard to race, religion, color, national origin, sex, sexual orientation, gender identity, age, status as a protected veteran, or status as a qualified individual with disability.

Interested individuals should send a CV, names of three references, and a cover letter with a brief statement of future research interests and career goals to:

[email protected] 

      Pavel Ivanov, PhD
      Associate Professor of Medicine / Associate Immunologist
      Brigham and Women's Hospital & Harvard Medical School