Postdoctoral Positions in RNA Epigenomics
Posted on August 6

Two postdoctoral positions are available in the laboratory of Gregory Matera in the Integrative Program for Biological and Genome Sciences, University of North Carolina at Chapel Hill, USA.

The Program is devoted to model-organism biology and it provides a highly collaborative environment, along with exceptional interdisciplinary opportunities for trainees. The Matera lab has broad interests in basic molecular mechanisms that regulate RNA processing and RNP assembly in vivo.  Using Drosophila as our primary genetic system, we engineer BAC-based histone gene clusters to express specific histone mutants that prevent binding of effector proteins in chromatin. These genetic and genomic studies directly evaluate the contributions of specific histone PTMs to epigenetic regulation during development and neoplasia. Concurrently, we also study RNP biogenesis mechanisms and innate immune signaling defects in animal models of neuromuscular disease. We use genetics and proteomics combined with a variety of deep sequencing approaches to understand fundamental questions in eukaryotic gene regulation.

Qualifications:
We are looking for enthusiastic, highly motivated and creative individuals with a strong interest in epigenetics, neuromuscular disease and chromatin biology. US Citizens and permanent residents can also apply for initial funding through the UNC Lineberger Comprehensive Cancer Center. Successful candidates for these positions are expected to have a PhD in the biological sciences, along with demonstrated experience in molecular genetics and genomics and/or Drosophila. Applicants with expertise (or interest) in bioinformatic training are especially encouraged to apply.

Contact:
Applicants should send a single PDF file containing a cover letter, curriculum vitae, and a short (1-2 pg) summary of their previous research experience and future goals. CV should include contact information for three references. Send to Greg Matera: [email protected]