Postdoctoral Position to Study the RNA Biology of Centrosomes

Posted on August 9,

The Taliaferro and Pearson labs at the University of Colorado Anschutz Medical Campus is seeking a postdoctoral fellow to start immediately to conduct research on the causes and consequences of RNA localization to centrosomes. 

The spatial organization of proteins within cells is critical to their proper function.  This spatial arrangement can be achieved by transporting fully translated proteins to their required destination. Alternatively, it can be done by transporting the instructions for making the protein, that is, an mRNA, to the desired location followed by on site protein production.  It has been recently observed that centrosomes are associated with a distinct localized transcriptome.  However, the nature of these RNA molecules, how they are trafficked to the centrosome, and the consequences of their mislocalization are all generally unclear.

Active areas of research include (1) determining the identities of centrosome-proximal RNAs and their dynamic localization across the cell cycle, (2) high-throughput screening to identify RNA sequences with the ability to drive localization to centrosomes, and (3) identifying cellular phenotypes associated with RNA mislocalization.

Research will involve wet-lab experimental procedures and computational analyses of high-throughput sequencing data.  Applicants with familiarity with only one of these techniques and the desire to increase experience with the other are encouraged to apply.

For additional information about the laboratory or to see recent publications, visit www.taliaferrolab.com and www.thepearsonlab.com.  For further information about the position or to apply, visit https://cu.taleo.net/careersection/2/jobdetail.ftl?job=10847&lang=en.  Interested applicants may also send an email to [email protected] and [email protected] for more information.

This position would be part of the Department of Biochemistry and Molecular Genetics, the RNA Bioscience Initiative, and the Department of Cell and Developmental Biology.  The highly collegial and energetic environment is full of exciting and varied research.  The city of Denver is a fantastic place to live and provides ample opportunity for cultural and outdoor activities.