Postdoctoral position open at the University of Massachusetts Medical School, in the Korostelev Lab
Posted on April

We study translation regulation, using cryo-EM and biochemistry. We are particularly interested in: (1) Translation accuracy; (2) Ribosome's central role in bacterial stress signaling and gene regulation; (3) Neurodegenerative and other diseases, which originate from dysregulation of translation. References to some lab publications are provided below. 

Our laboratory is housed at the RNA Therapeutics Institute, a vibrant and highly interactive research community: Our colleagues are interested in nearly all aspects of RNA biology, from small to large RNAs to RNA chemistry and therapeutics development.

We seek a highly motivated person who very recently received a PhD, or will soon receive a PhD.  Applications sent prior to the dissertation defense date are welcome. 

Please submit the following information via email to: [email protected]

1)      your CV (including publication list);
2)      in less than 2 pages, an outline of your:
     (i) previous work - focusing on your most interesting finding(s);
     (ii) your current/future scientific interests, and whether/which aspects of translation regulation sound interesting to you;
3)      email addresses of three references. 

Selected publications (accessible via the provided links):
-      Svidritskiy et al. “Extensive ribosome and RF2 rearrangements during translation termination”. eLife. 2019.
-      Loveland et al. “Ensemble cryo-EM elucidates the mechanism of translation fidelity”. Nature. 2017.
-      Demo et al. “Structure of RNA polymerase bound to ribosomal 30S subunit”. eLife. 2017.
-      Abeyrathne et al. “Ensemble cryo-EM uncovers inchworm-like translocation of a viral IRES through the ribosome”. eLife. 2016.
-      Loveland et al. “Ribosome•RelA structures reveal the mechanism of stringent response activation”. eLife. 2016.