Postdoctoral position in RNA splicing at Paris-Saclay University (France)

Posted on November 3,

The SABNP laboratory is seeking for a postdoc candidate to work in the field of RNA splicing in the Alexandre Maucuer's group. This dynamic team is involved in the deciphering of critical molecular interactions for splicing. In particular we focus on 3' splice site recognition mechanisms that are altered in numerous cancers (PMID: 31271494, PMID: 34520118). For this we use a variety of techniques including protein-protein interactions, structural NMR-based analyses, HCS fluorescence microscopy, RNAseq and other large dataset analyses among others.

The candidate will choose between two projects according to his/her experience and interests:

The first project concerns the study of recently identified interactions for key splicing factors. The candidate should have a good background in biochemistry, cell biology and molecular biology techniques.

The second project aims at characterizing a network of interactions using bioinformatics approaches. For this project, the candidate should have experience in or strong motivation to learn one or more programming languages (ideally python, shell or R), and interest in RNAseq or related dataset analyses. Knowledge of wet lab techniques is a plus.

Qualification: Ph.D. in Biology, Biochemistry, Computer Science, or related disciplines.

The successful candidate will be highly motivated, able to multi-task efficiently, work independently and be committed to research. In addition a good sense of humor, engagment, organization skills  and action-biased disposition are wellcome.

Eligibility: Candidates have not been working in France for more than 12 months in the last three years. See https://apogeebio.genopole.eu/application-file/ for the detailed eligibility rules.

Laboratory: The SABNP laboratory, located at the Genopole biocluster, is part of the prestigious university Paris-Saclay. The lab focuses its research on the structure and function of RNA: Protein complexes and aims to develop applications in medicine and biotechnology (http://sabnp.univ-evry.fr/?lang=en).

Net salary: ~3,000 euros. These internships will be funded by the ApogeeBio 2023 program (Genopole/European commission).

Contact: alexandre.maucuer[at]inserm.fr. To apply, please provide a CV with a brief statement of research interests and contact information for references before 01/15/2023. Please indicate your favorite project and how you find out about this offer in your mail.

Start date: ideally between 06/01/2023 and 10/01/2023.