Postdoctoral position – RNA neurobiology, genomics, molecular biology

Posted on October 8,

A postdoctoral position is available in the Campbell lab in the Department of Anesthesiology at UW-Madison. The lab is interested in understanding how the translational landscape of pain sensing neurons is shaped by noxious cues. We use functional genomics approaches such as ribosome profiling to identify targets and make use of pharmacology and genome editing to validate our findings. We are particularly interested in elucidation of general mechanisms of mRNA control that drive acute and persistent forms of pain. Here are several representative publications:

de la Peña JB, Barragan-Iglesias P, Lou TC, Loerch S, Kunder N, Shukla T, Song J, Megat S, Moy JK, Wanghzou A, Ray PR, Hoyt K, Steward O, Price TJ, Shepherd J, Campbell ZT*. Intercellular Arc signaling regulates vasodilation. J Neuroscience. 2021. 37: 7712-7726

Smith PR, Loerch S, Kunder N, Stanowish AD, Lou TZ, Campbell ZT*. Functionally distinct roles for eEF2K in the control of ribosome availability and p-body abundance in sensory neurons. Doi: 10.1038/s41467-021-27160-4. Nature Communications. 2021. 12 (1): 1-16

Barragán-Iglesias P, Lou TF, Bhat V, Megat S, Burton M, Price T, Campbell ZT*. Inhibition of Poly(A)-Binding Protein with an RNA mimic reduces pain sensitization in mice. Nature Communications 2018. 9(1):10

Zhou Q, Kunder N, De la Paz JA, Lasley AE, Morcos F, Campbell ZT*. Global pairwise RNA interaction landscapes reveal core features of protein recognition. Nature Communications 2018. 9(1):2511

A full list can be found here: https://pubmed.ncbi.nlm.nih.gov/?term=Campbell+ZT&sort=pubdate

The lab has access to state of the art imaging equipment, protein purification equipment, Cryo-EM facilities, high-throughput sequencing, hiPSC editing, and a vivarium.

Requirements: Ph.D. or an M.D. in molecular biology, biochemistry, RNA biology, or a related discipline, self-motivated, excellent communication skills, and desire to lead innovative and rigorous research projects.

To apply send a copy of your CV with a brief (1 paragraph statement) of research interests and contact information for three refences to Dr. Zachary Campbell [email protected]