Postdoctoral position - RNA localisation and the control of endothelial cell morphology

Posted on January 31,

The G.Costa lab, Queen’s University of Belfast, is recruiting a Postdoctoral researcher to join a Wellcome Trust funded project investigating RNA localisation in the context of endothelial cell biology ( Upon transcription, RNAs are distributed throughout the cell and their ultimate functional destination underpins a multitude of cellular processes. Our work has demonstrated that RNA localisation participates in endothelial cell behaviour during blood vessel formation (Costa et al., EMBO J 2020). Based on these concepts, we are seeking a highly ambitious and motivated individual to explore mechanistic links between subcellular RNA distribution and cell adhesion in the context of vascular biology. By combining state-of-the-art proteomics, transcriptomics and imaging tools with in vivo and in vitro models of blood vessel formation and maintenance, we aim to bring new insights into the importance of RNA localisation in tissue physiology and disease.

The successful candidate will be a fundamental pillar to the project. They will take the lead planning and performing experiments, as well as strengthening established collaborations. The post is available for 4 years, through which the successful candidate will be offered support to access diverse training and career development opportunities.

The successful candidate must have:

  • Obtained or are about to obtain a PhD in Vascular Biology, Cell Biology, RNA Biology or closely related area.
  • At least 3 years recent, hands-on experience in a wide range of laboratory skills relevant for this project, such as cell culture, RNA manipulation, RNA-protein interactions and immunoprecipitation.
  • Authorship in at least one manuscript published in an internationally recognised peer reviewed journal. This should be commensurate with stage of career and experience.

Apply until 20th February 2023: