Postdoctoral Associate - Ke Lab
Posted on August 4

The Laboratory of Dr. Shengdong Ke has one postdoctoral associate opening at The Jackson Laboratory in Bar Harbor, Maine. The Ke Lab focuses on RNA, a central node of genetic information flow from DNA to protein (https://www.jax.org/research-and-faculty/faculty/shengdong-ke). Malfunction of RNAs leads to many human diseases, including neurological diseases and cancer. To thoroughly address fundamental molecular mechanisms of RNA genomics, the Ke lab utilizes multidisciplinary approaches, including computational biology, biochemistry, innovative biotechnologies, genetics and molecular biology. We are especially interested in the fundamental mechanism of m6A RNA genomics; and regulation of m6A RNA genomics in neurological disease and cancer, using mouse and human iPS models. (References: 1] Ke, S. et al. m6A mRNA modifications are deposited in nascent pre-mRNA and are not required for splicing but do specify cytoplasmic turnover, Genes & Development 2017, 31: 990-1006; 2] Ke, S. et al. A majority of m6A residues are in the last exons, allowing the potential for 3' UTR regulation, Genes & Development 2015, 29:2037-53.)

Requirements:
Qualified candidates will be self-motivated and career oriented individuals, have a genuine interest in addressing complex biological questions, and have a Ph.D. or MD. degree with background in one of the following areas, including biochemistry, molecular biology, biotechnology, neurosciences, immunology, stem cell, cancer biology or computational biology. Biochemistry and/or computational background and interest is a plus. https://careers-jax.icims.com/jobs/25557/postdoctoral-associate---ke-lab/job 

The Jackson Laboratory (http://www.jax.org) in Bar Harbor, Maine, USA is a world leader in mammalian genetics.  JAX is passionate about its mission of discovering precise genomic solutions for disease and empowering the global biomedical community in the shared quest to improve human health. JAX is recognized internationally for its excellence in research, unparalleled mouse resources, outstanding training environment characterized by scientific collaboration and exceptional core services - all within a spectacular setting adjacent to Acadia National Park. In addition to lab-based training, JAX has developed a unique program for trainees to expand their professional skills in science communication, entrepreneurship, teaching, mentoring and laboratory management to best prepare postdocs for future career opportunities.