Postdoc position in single molecule imaging and multi-omics analysis of mRNA translation

Posted on March 28,

Swiss Federal Institute of Technology in Lausanne (EPFL)

The Naef lab for at the Faculty of Life Sciences at the Swiss Federal Institute of Technology in Lausanne (EPFL) has an opening for a postdoctoral fellow to join the lab’s longstanding research program on temporal gene regulatory mechanisms, and notably the regulation of translation dynamics in relation to the feeding-fasting and circadian cycles.

This position is funded in the context of a collaborative SNSF Sinergia grant Integrated multi-scale analysis of translation: single-molecules, omics and computation with Jeff Chao (FMI Basel) and Pierre Vandergheynst (EPFL). We are looking for a highly motivated new team member to further develop Molecular and computational tools for bulk and single-molecule translation experiments, or to perform a Quantitative dissection of the translation cycle in response to nutrient stress.

We are specifically looking for interdisciplinary profiles holding a PhD in molecular or computational biology (or a closely related field) with a strong background in areas such as

  • single molecule imaging (SunTag)
  • omics technologies (Ribo-seq, RNA-seq, mass spectrometry)
  • computational multi-omics analysis

The team member will generate and/or analyze high-throughput sequencing data including (but not limited to) Ribo-seq, RNA-seq, or perform single molecule imaging of mRNAs using SunTag reporters. The successful candidate will work independently to develop and drive forward his/her research project, and also collaborate on ongoing projects in the group. Quantitative and interdisciplinary training, as well as previous experience with statistics, math/physics/computation, or next-generation sequencing genomic data analysis will be highly considered.

For more information, please contact [email protected]

Lab website:

To apply, please send your complete application in a single PDF file, including a cover letter, full CV and the contact information of 3 referees, to [email protected]. Submitted applications will be evaluated immediately, and the search will remain open until the position is filled.

Start date: the position is immediately available (spring 2022) but the starting date is flexible

Contract: 1 year, renewable, maximum 4 years.