Employment Opportunities

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Postdoctoral Position Available, RNA Chemical Biology, Lab of Prof. Ralph Kleiner, Princeton University

A postdoctoral position in RNA Chemical Biology is available in the lab of Professor Ralph Kleiner at Princeton University.

A PhD in Chemistry, Biology or a related field is required. Candidates with expertise in any of the following areas are encouraged to apply: nucleic acid chemistry, RNA biochemistry, protein biochemistry, bioinformatics, and cell biology.

The start date for the position is negotiable. Please send applications containing your CV, cover letter, and a list of 3 references to rkleiner@nullprinceton.edu.

Three Post-Doctoral Positions To Study Mechanisms Of Translation And Translation-Associated Quality Control Processes In Eukaryotes

Three postdoctoral research positions are open in the laboratories of Tatyana Pestova and Christopher Hellen at the State University of New York Downstate Medical Center in Brooklyn, NY, USA. Our NIH-funded research uses state-of-art biochemical and molecular biology approaches to characterize molecular mechanisms of (1) canonical and non-canonical modes of translation initiation in mammals, including IRES-mediated initiation, (2) physiologically important specific cases of translational regulation, (3) translation elongation, termination and ribosome recycling, and (4) events downstream of termination, with a major focus on quality control processes, including mRNA surveillance and ribosome-associated quality control.

Required qualifications include a Ph.D. in Molecular Biology/Molecular Biochemistry, and practical experience in RNA and/or protein biochemistry, including the expression and purification of native/recombinant proteins and the functional analysis of proteins and RNA-protein complexes. Experience in investigating aspects of eukaryotic translation and associated quality control processes will be highly appreciated. Our research involves active collaborations with leading cryoEM laboratories, and experience in structural biology would therefore be helpful.  Candidates should be highly motivated, be able to work independently and show excellent critical thinking, scholarly ability and communication skills.

These positions carry a salary of $45,000 – $60,000 (depending on experience) plus benefits, including health insurance. Review of applications will begin immediately until the positions are filled. To apply, please send a cover letter discussing your interest in a position and mentioning the expected availability date, your curriculum vitae (including a summary of research experience, including techniques and methods used, and a list of publications) and contact information for three references to:

christopher.hellen@nulldownstate.edu
or
Tatyana.pestova@nulldownstate.edu

As an Equal Opportunity / Affirmative Action employer, the Research Foundation will not discriminate in its employment practices due to an applicant’s race, color, religion, sex, national origin and veteran or disability status. Personnel are chosen on the basis of ability without regard to Race, Color, Religion, Sex, Age, National Origin, Disability or Marital Status in Accordance with Federal and State Law.

Postdoctoral Researcher Position Available Immediately, Laboratory of Dr. Mingyi Xie

Postdoctoral Researcher position available immediately in the Laboratory of Dr. Mingyi Xie (Assistant Professor, Department of Biochemistry and Molecular Biology,

Cancer Center, University of Florida) to study the Function and biogenesis of alternatively-processed microRNAs and Integrator complex-mediated RNA processing. Postdoc salary starts at $47,476 per year.

Applicants should submit the following to mingyi.xie@nullufl.edu:

1)      Cover letter stating: laboratory experience in RNA/protein biochemistry and/or bioinformatics; your long-term career goals; date of availability to begin postdoc research

2)      Curriculum vitae (including publications and awards/honors)

3)      List of at least three references

Visit Xie lab website: xie.biochem.med.ufl.edu for more information.

Postdoctoral Fellow Positions Available, Lab of Dan Herschlag

The laboratory of Dan Herschlag (herschlaglab.stanford.edu) is looking for motivated,
creative and interactive candidates in the following areas:
• RNA tertiary folding: We have developed an RNA Reconstitution Model as a
conceptual framework that can in principle provide quantitative predictions of RNA
folding stability and rates. Continued high-throughput thermodynamic measurements
with the Greenleaf lab (Stanford) will provide the foundation for determining the
conformational landscapes, or ensembles, for individual RNA motifs that can be
combined to predict the folding properties of complex RNAs and RNA/protein
complexes.
(See DOI: 10.1016/j.cell.2018.05.038 and DOI: 10.1101/cshperspect.a032433)
• RNA/protein interactions: Using the Greenleaf platform, we have for the first time
obtained a fully predictive model for RNA/protein binding. We are interested in
deepening our understanding of RNA/protein recognition and in applying this model to
identify and quantitate the cellular features that determine RNA/protein interactions in
vivo using Quantitative Cellular Biochemistry, which entails parallel high-throughput
quantitative measurements in vitro and in cells.
(See DOI: http://dx.doi.org/10.1101/403006)
The lab provides an excellent training environment and is located in a highly
collaborative and interdisciplinary environment at Stanford. Salary is adjusted for
California’s cost of living. To apply, please send (1) a cover letter, with your specific
research interests in relation to the above project and broader lab research, as well as your
training and career goals; (2) C.V.; and (3) names and contact information of three
references to Morgan Williams (mwillia@nullstanford.edu).

Postdoctoral Fellow Position Available, University Of Rochester School Of Medicine

The Ermolenko lab at the University Of Rochester School Of Medicine (https://www.urmc.rochester.edu/labs/ermolenko.aspx)  is looking for a postdoctoral fellow to study the role of the intrinsic closeness of mRNA ends in protein synthesis (please see our recent publication on this topic https://www.nature.com/articles/s41467-018-06792-z). We use biochemical approaches and single-molecule fluorescent microscopy. The position is immediately available and will remain open until filled. Applicants with recent PhD in biochemistry or molecular biology are invited to email their CV and cover letter to Dmitri_Ermolenko@nullURMC.Rochester.edu.