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Postdoctoral Associate Position in RNA Biology

The Kiledjian laboratory in the Dept. Cell Biology & Neuroscience at Rutgers University is seeking an outstanding postdoctoral associate to study the regulation of RNA turnover in the control of gene expression. The laboratory is interested in understanding the molecular mechanism by which 5´ end cap epitranscriptomic modifications such as a nicotinamide adenine diphosphate (NAD) cap (see Jiao et al., 2017 Cell; Grudzien-Nogalska et al., 2019 Nature Chemical Biology) or m6Am cap (see Mauer et al., 2017 Nature) regulate RNA levels and gene expression. Other areas of investigation include the role of decapping proteins in human cognitive disability. Please refer to the Kiledjian Lab web page (https://cbn.rutgers.edu/kiledjian-lab-home) for more information on research areas of interest in the lab.

We are seeking highly motivated candidates with a Ph.D. in molecular/cellular biology or a related discipline with good communications skills and a publication track record in peer reviewed journals.  Preference will be given to applicants with research experience in the areas of post-transcriptional gene regulation, RNA metabolism and computational biology.

Interested individuals should apply by email (Kiledjian@nullbiology.rutgers.edu) to Mike Kiledjian, Ph.D., and include a cover letter describing interests and past accomplishments, a current curriculum vitae, and contact information for three references.

Postdoctoral Position Available

A post-doctoral position is available in the group of Michael Jantsch, studying the interaction of the RNA-editing enzyme ADAR1 with its transport protein tranportin1. This interaction is regulated by RNA-binding and seemingly controls the shuttling behavior of this protein. In a collaborative research grant with the structural biologist Pierre Barraud in Paris, the interaction between transporter and cargo and its regulation via RNA-binding shall be studied.

The work will involve construction of fusion proteins and mutations thereof, binding assays, nuclear import assays, RNA-crosslinking assays, and cell transfection assays

The position is funded for  up to 24 months following Austrian Post doctoral salaries of ~67k€ gross annual salary. The position is open immediately.

If interested, please send your application together with a motivation letter and a CV to Michael.Jantsch@nullmeduniwien.ac.at

For background on this project see: https://www.pnas.org/content/111/18/E1852.short?rss=1

Two Postdoctoral Positions Available, Kwok Lab, Dept of Chemistry, City University of Hong Kong

Two postdoctoral positions (one RNA biologist, one bioinformatician) are available immediately at the Kwok Lab, Department of Chemistry, City University of Hong Kong. (www.kitkwok.com)

Our research focus is to develop chemical and biochemical technologies to decipher the hidden layers of information in RNA such as RNA structures; identify the RNA binding partners and molecular basis of interactions; and elucidate the mechanistic roles of RNA in regulatory pathways, stress physiologies, cell differentiation, organism development, as well as disease pathology. Interested candidates may referred to our recent reviews, e.g. PMID 30853244, PMID 30459069, PMID 29967010, PMID 28755976

Candidates with excellent molecular biology, chemical biology, and/or biochemistry will be considered for the RNA biologist postdoc post.

Candidates with excellent computational skills in transcriptomics and related areas will be considered for the bioinformatician postdoc post.

Qualified candidates should have recently accomplished their Ph.D. degree and have strong written and spoken english.

Candidates should send their Curriculum Vitae and a cover letter summarizing:

– A description of research accomplishments.

– Research interests in RNA and transcriptomics.

– Contact information for two references to: Chun Kit Kwok, Ph.D. mailto:ckkwok42@nullgapps.cityu.edu.hk

 

RNA Biologist, Sixfold Bioscience, London

At Sixfold we’re building a better way to deliver cures. We see the huge potential of Cell and Gene therapies being limited by how safely and effectively they can be systemically delivered in people. Our scientists are creative and iterate fast because they want to see what they do in the lab make a difference in the clinic.

Job summary
We’re seeking a highly motivated and independent RNA Biologist to join our team. Specifically, we are looking for an experienced scientist who is passionate about transforming how we cure disease. As a rapidly growing start-up, your work will make invaluable contributions to the scientific and strategic direction of the company.

What you’ll do

  • Develop novel assays to test the efficacy and safety of Sixfold’s technology.
  • Design and execute robust laboratory experiments, interpret data, communicate findings, and maintain high-quality records.
  • Work closely with Sixfold’s chemistry and computational team.
  • Supervise junior members of staff.
  • Support and contribute to publishing and grant writing efforts.

Requirements

  • PhD in Cell biology, Molecular biology or a related discipline.
  • Expertise in RNA biology

Extra credits

  • Cellular and molecular biology techniques, including: PCR, DNA/RNA transfections, immunofluorescence, flow cytometry, confocal microscopy, WesternBlotting, histology and qPCR.
  • Design and optimisation of RNA-based therapeutics such as mRNA and siRNA.
  • Ability to create and implement new assays.
  • Generation of engineered cell lines and prior experience in generating complex DNA constructs for gene expression.
  • Drug delivery experience.

Who you are

  • Use creativity and scientific intuition for designing and undertaking experiments.
  • Can work in a highly collaborative research environment.
  • Drive innovative research through the application of new techniques and technology, as well as internal and external collaborations.
  • Have a desire to work in a dynamic and fast-paced environment.

Perks

  • Competitive salary based on experience.
  • Equity based remuneration.
  • Dynamic, innovative, passionate and entrepreneurial team.
  • Flexible hours.
  • The chance to see your ideas and research make an impact in a fast-growing start-up.
  • Work at the Translation & Innovation Hub (I-HUB), home to a vibrant international start-up community (and free coffee!).
  • Team-wide social events.

About us
Located in London, Sixfold is a YCombinator and venture-backed startup. Founded by researchers from the University of Cambridge and the Francis Crick Institute, we’re dedicated to expanding the potential of Cell and Gene therapies, so that ultimately we can cure more diseases in more people. It’s why we started Sixfold — to make a difference. We work at the cutting edge of science by fostering collaborations with the world’s best institutions and the sharpest minds. If you want to help cure the incurable, you belong with us.

It’s important to mention that although disease affects us all, our industry still displays a huge lack of diversity — this needs to change. Our founding team is comprised of different nationalities and is 2/3rds female founders. Our goal is to create a company culture that promotes ideas and the inclusion of scientists and engineers from all backgrounds.

Find out more

 

Organic Chemist, Sixfold Bioscience, London

At Sixfold we’re building a better way to deliver cures. We see the huge potential of Cell and Gene therapies being limited by how safely and effectively they can be systemically delivered in people. Our scientists are creative and iterate fast because they want to see what they do in the lab make a difference in the clinic.

Job summary
We’re seeking a highly motivated and independent Organic Chemist to join our team. Specifically, we are looking for an experienced scientist who is passionate about synthesising molecules to transform how we cure disease. As a rapidly growing start-up, your work will make invaluable contributions to the scientific and strategic direction of the company.

What you’ll do
● Design new synthesis strategies and compounds
● Synthesise molecules used in Sixfold’s technology
● Optimise synthesis routes

Requirements
● PhD in Organic Chemistry
● Experience in total synthesis of small molecules.
Extra credit
● Expertise in Drug delivery methods
● Experience with conjugation methods such as click chemistry and disulfide bond formation
● Expertise in analytical techniques including HPLC, LC-MS GC-MS.

Who you are
● Use creativity and scientific intuition for designing and undertaking experiments.
● Can work in a highly collaborative research environment.
● Drive innovative research through the application of new techniques and technology, as well as forming internal and external collaborations.
● Have a desire to work in a dynamic and fast-paced environment.

Perks
● Competitive salary based on experience.
● Equity based remuneration.
● Dynamic, innovative, passionate and entrepreneurial team.
● Flexible hours.
● The chance to see your ideas and research make an impact in a fast-growing start-up.
● Work at the Translation & Innovation Hub (I-HUB), home to a vibrant international start-up community (and free coffee!).
● Team-wide social events.

About us
Located in London, Sixfold is a YCombinator and venture-backed startup. Founded by researchers from the University of Cambridge and the Francis Crick Institute, we’re dedicated to expanding the potential of Cell and Gene therapies, so that ultimately we can cure more diseases in more people. It’s why we started Sixfold — to make a difference. We work at the cutting edge of science by fostering collaborations with the world’s best institutions and the sharpest minds. If you want to help cure the incurable, you belong with us.

It’s important to mention that although disease affects us all, our industry still displays a huge lack of diversity — this needs to change. Our founding team is comprised of different nationalities and is 2/3rds female founders. Our goal is to create a company culture that promotes ideas and the inclusion of scientists and engineers from all backgrounds.

Find out more
● For more info see: https://www.sixfold.bio
● Informal enquiries email: careers@nullsixfold.bio
● To apply: http://bit.ly/sixfold-job-app

Postdoc Position Available at Vinther Lab, Department of Biology

A 30 months postdoc position is available at Vinther Lab, Department of Biology, University of Copenhagen. The position will be available as of 1 August 2019.

The project is focused on the analysis of the consequences of oxidative signaling and damage on the transcriptome. The postdoc will be responsible for performing sequencing based experiments to map and analyse oxidation of specific RNA positions using cell culture model systems and sequencing based mutational profiling.

The Vinther Lab has extensive experimental and computational knowhow related to implementation of sequencing based methods and the analysis of the data. We maintain an informal, collaborative and productive working environment at the interface of experimental RNA biology and Bioinformatics. Recent publications by the Vinther Lab: PMID 29126318 26220183, 25805860, 24569351.

Qualifications:

I am looking for highly motivated individuals with a PhD degree. Candidates with some experience with massive parallel sequencing based experiments, Iron Biology, Reactive Oxygen Species or RNA Biology/Biochemistry will be preferred.

For consideration, applicants must:

  • Have a PhD in molecular biology, biochemistry, medicine or a similar field
  • Have published in international peer-reviewed journals

The working language is English, thus excellent English speaking, reading and writing skills are required.

For further information about the position, please contact Associate Professor Jeppe Vinther (jvinther@nullbio.ku.dk). The application deadline is May 15, 2019. To apply for the position use this link: https://candidate.hr-manager.net/ApplicationInit.aspx?cid=1307&ProjectId=149398&DepartmentId=18965&MediaId=4636&SkipAdvertisement=true

Two positions in Chemical Biology

Postdoctoral Researcher

The Krauss lab is seeking a postdoctoral researcher with experience in nucleic acids, ideally RNA and in vitro selection and mRNA display. The position is open immediately, but other start dates through 2019 will be considered. Please send CV and/or research summary and contact information for three references to kraussi@nullbrandeis.edu, with the word “application” in the subject line.

The Krauss lab does research in chemically modified libraries for in vitro selection. This researcher will take part in projects involving in mRNA display selections of peptides that are post-translationally modified with carbohydrates, to develop selective glycopeptide binders of lectins, mimics of glycosaminoglycans, and HIV vaccine candidates (see http://dx.doi.org/10.1021/ja411212q and http://dx.doi.org/10.1021/ja500678v,  for lead references).

Technician

The Krauss lab seeks a technician with basic molecular biology skills, ideally experience with nucleic acids/RNA and protein expression. This person will be responsible for preparation of proteins and RNAs used in in vitro translation experiments. The position is open immediately, but other start dates through 2019 will be considered. Please send CV and/or research summary and contact information for three references to kraussi@nullbrandeis.edu, with the word “application” in the subject line.

A Post-Doctoral Position To Study Mechanisms Of Translation And Translation-Associated Quality Control Processes In Eukaryotes

A postdoctoral research position is available in the laboratory of Tatyana Pestova and Christopher Hellen at the State University of New York Downstate Medical Center in Brooklyn, NY, USA. Our NIH-funded research uses state-of-art biochemical and molecular biology approaches to characterize molecular mechanisms of (1) canonical and non-canonical modes of translation initiation in mammals, including IRES-mediated initiation, (2) physiologically important specific cases of translational regulation, (3) translation elongation, termination and ribosome recycling, and (4) events downstream of termination, with a major focus on quality control processes, including mRNA surveillance and ribosome-associated quality control.

Required qualifications strictly include a Ph.D. in Molecular Biology/Molecular Biochemistry, and practical experience in RNA and/or protein biochemistry, including the expression and purification of native/recombinant proteins and the functional analysis of proteins and RNA-protein complexes. Experience in investigating aspects of eukaryotic translation and associated quality control processes will be highly appreciated. Our research involves active collaborations with leading cryoEM laboratories, and experience in structural biology would therefore be helpful.  Candidates should be highly motivated, be able to work independently and show excellent critical thinking, scholarly ability and communication skills.

These positions carry a salary of $45,000 – $60,000 (depending on experience) plus benefits, including health insurance. Review of applications will begin immediately until the positions are filled. To apply, please send a cover letter discussing your interest in a position and mentioning the expected availability date, your curriculum vitae (with a summary of research experience, including techniques and methods used, and a list of publications) and contact information for three references to:

christopher.hellen@nulldownstate.edu

or

tatyana.pestova@nulldownstate.edu

As an Equal Opportunity / Affirmative Action employer, the Research Foundation will not discriminate in its employment practices due to an applicant’s race, color, religion, sex, national origin and veteran or disability status. Personnel are chosen on the basis of ability without regard to Race, Color, Religion, Sex, Age, National Origin, Disability or Marital Status in Accordance with Federal and State Law.

Postdoctoral Position is immediately available in the Whipple laboratory at Harvard University

A postdoctoral position is immediately available in the Whipple laboratory at Harvard University to study the function of imprinted non-coding RNAs in neurophysiology and disease (whipplelab.com). We seek a highly motivated individual with an interest in RNA biology, neurobiology, and/or computational biology to join our team.

Imprinted genes play important and complex roles in the development of the mammalian brain, including roles in growth, behavior, maternal care, and learning. The importance of imprinted genes in the brain is further highlighted by the wide variety of neural and behavioral phenotypes associated with their misexpression. Our laboratory is interested in understanding the function of small and long non-coding RNAs that are expressed from imprinted regions in neurons. We have developed an in vitro neuron differentiation system that allows for quantification of allelic expression and are using this system to decipher functions of imprinted long non-coding RNAs, microRNAs, and small nucleolar RNAs employing a variety of molecular, cellular, and transcriptomic assays.

Successful candidates will have recently obtained a Ph.D. in a relevant field, demonstrated productivity through publication, and be able to clearly convey difficult scientific concepts through excellent written and oral communication. Experience with bioinformatics is strongly encouraged.

To apply for the position, please submit a cover letter containing a description of your (1) previous/current research and (2) your future research interests. Also submit your CV including contact information for three references. Materials may be submitted to Amanda Whipple at amanda_whipple[at]fas.harvard.edu.

Postdoctoral position in post-transcriptional control of innate immune gene expression

A postdoctoral position is available in the Department of Microbial Pathogenesis and Immunology at Texas A&M Health Science Center to study post-transcriptional regulation of the innate immune response to infection.

We are looking for a motivated, hard-working researcher to join the NIH-funded lab of Drs. Kristin Patrick and Robert Watson. The main goal of our collaborative effort is to investigate how pre-mRNA splicing is regulated during infection and how changes to splicing impact innate immune outcomes. Using a variety of approaches (RNA/protein biochemistry, mammalian genetics, RNA-seq/bioinformatics, and mouse models of infection), we are looking to understand how splicing complexes are remodeled downstream of pathogen sensing events and how post-trasnlational modification of splicing factors impacts their ability to read and interpret the splicing code. See our new pre-print for a taste of what we do: https://www.biorxiv.org/content/10.1101/617043v1

We are a young, dynamic lab dedicated to mentoring trainees and fostering a healthy and supportive space for postdocs to develop into independent researchers. Candidates with a Ph.D. in Biology or a related field and a strong background in molecular biology, RNA biology, and/or immunology are encouraged to apply.

Texas A&M Health Science Center is located in Bryan/College Station, TX a growing but still affordable and accessible mid-sized city in Central Texas.

Please email a (1) cover letter (2) CV and (3) contact information of at least 3 references to kpatrick@nullmedicine.tamhsc.edu. Visit www.thepatrickwatsonlab.com for more information.

Postdoctoral Position Available, Nicoli Lab, Dept of Genetics and Internal Medicine, Yale University

One postdoctoral position is available at the Nicoli Lab, Department of Genetics and Internal Medicine, Yale University, New Haven, CT USA.

The goal of our laboratory is to combine RNA-based mechanisms, genomics, and genetics in embryonic development to uncover new endothelial cell behaviors in vascular development and homeostasis. Our laboratory contributed to this research field with several publications available at nicolilab.com (most relevant for this job posting are Kasper bioRxiv 2019, Moro Nat. Cell Bio. 2019, Kasper Dev. Cell 2017, Narayanan Sci. Rep. 2016)

Area of interests in the Nicoli Lab:

1) Define RNA-based regulations occurring during mechanotransduction. The central question is to understand how translational and regulation of biomechanical genes control cell behaviors dictated by the extracellular matrix and/or blood flow-hemodynamics.

2) Define the functional effect of multigene miRNA families on developing vascular treats. The central question is to assign function to complex miRNA genes using an endothelial single cell phenotypic screening in zebrafish miRNAs knockouts.

3) Define Cis-regulatory RNAs that determine vascular cell behaviors. The central question is to decode sequences on the RNA that control common or tissue specific homeostatic endothelial cell behaviors.

Candidates with excellent molecular biology and/or microscopy skills will be considered. Computational skills are preferable but not necessary. Candidates are required to have strong interpersonal skills and outstanding written and spoken English to collaborate with a diverse team of scientists. Qualified candidates should have recently accomplished their Ph.D. degree (possibly no more than 1 year).

Candidates should send their Curriculum Vitae and a cover letter summarizing:

– A description of accomplishments.

– Research interests in RNA and/or Development and/or Vascular Biology.

– Contact information for three references to: Stefania Nicoli, Ph.D. stefania.nicoli@nullyale.edu

POSTDOCTORAL POSITION AVAILABLE IMMEDIATELY IN NEW YORK

NIH-funded postdoctoral position is available immediately at the Albert Einstein College of Medicine to study the cellular impact of the bone marrow failure syndrome dyskeratosis congenita (DC) by working on ribonucleoproteins. The ideal candidate will have a strong background in molecular cell biology and biochemistry with specific training in tissue culture, microscopy, and RNAseq.

Albert Einstein College of Medicine is a vibrant scientific community that caters to postdoctoral researchers through its Belfer Institute for Advanced Biomedical Studies. Postdoctoral housing is available. For more details check out the webpage of the Belfer Institute:

http://www.einstein.yu.edu/research/belfer-institute/

Interested candidates should send their CV, the addresses of three references (including email and phone number), and a cover letter with past achievements and current and future research interests to tom.meier@nulleinstein.yu.edu

http://www.einstein.yu.edu/faculty/5249/u–thomas-meier/

Postdoctoral Position Available, Dept of Otorhinolaryngology, University of Pennsylvania Perelman School of Medicine

Description

A postdoctoral position is available in the laboratory of Elizabeth White, Ph.D., in the Department of Otorhinolaryngology at the University of Pennsylvania Perelman School of Medicine. https://www.med.upenn.edu/whitelab/ We are interested in extending our virology and cancer biology expertise into the area of interactions between viruses and host RNA processing.

The laboratory studies the molecular biology of human papillomaviruses (HPVs). We have previously used systematic protein-protein interaction and transcriptional analyses to conduct broad studies on papillomaviruses and the host cells they infect. We continue to investigate the host cell targets identified in these analyses as well as to initiate new systematic approaches to identify and study viral targets. Our overall goal is to understand the molecular mechanisms by which HPVs modulate host immune responses and cause oncogenic transformation, and projects are available in each of these broad areas. The laboratory routinely uses molecular and cell biological techniques as well as computational biology, mass spectrometry, high-throughput screening approaches, and more to investigate HPV biology. For an example of our recent work, see PNAS (2019) 116:7033-7042.

The Department of Otorhinolaryngology within the Perelman School of Medicine provides an outstanding environment for postdoctoral training. Our departmental colleagues include world-class physicians and basic scientists and our laboratory space is adjacent to the Department of Microbiology. Penn is also home to many outstanding tumor virology laboratories, the Abramson Cancer Center, and the Tumor Virology Program. There are abundant opportunities for collaboration with these and other groups at Penn, within the department of Otorhinolaryngology, and at neighboring institutions.

Qualifications

A doctoral degree (Ph.D. and/or M.D.) in the biological sciences and expertise in virology, cancer biology, or a related field, is required. Candidates must also have a collegial attitude, strong work ethic, and excellent communication and technical skills.

Contact: eawhite@nullpennmedicine.upenn.edu

Postdoctoral Position at Johns Hopkins University

A postdoctoral position is available in the laboratory of Dr. Ryuya Fukunaga at Johns Hopkins University School of Medicine. The laboratory is focused on understanding RNA biology, including the molecular mechanisms of (1) biogenesis and function of small silencing RNAs such as miRNAs and siRNAs, (2) post-transcriptional gene regulation by RNA-binding proteins, RNases, RNA helicases, and RNA modification enzymes.

We employ a wide range of approaches that include biochemistry, Drosophila genetics, cell culture system, high-throughput sequencing, and structural analysis.

We are looking for a highly motivated and enthusiastic new member of the lab. Candidates must have received (or be expecting) a Ph.D. or M.D. within the past three years in molecular biology, biochemistry, genetics, cell biology, structural biology, or a related discipline. Candidates with strong background in biochemical, molecular, cellular, and genetic analyses in RNA biology and/or Drosophila genetics are encouraged to apply.

More information is available at:

https://sites.google.com/site/fukunagalabjhmi/

https://bcmb.bs.jhmi.edu/people/faculty/ryuya-fukunaga

 

Please email [1] cover letter, [2] CV, [3] a brief summary of research interests, accomplishments, and career goals, and [4] contact information of at least three references to Dr. Ryuya Fukunaga at fukunaga@nulljhmi.edu

Postdoctoral Position in RNA splicing dysregulation and oncogenesis, Beckman Research Institute

The Wang laboratory is seeking a talented and motivated Postdoctoral Fellow to lead the project for understanding RNA splicing dysregulation (SF3B1 mutation, occurs in 20% chronic lymphocytic leukemia) and oncogenesis in blood malignancies. We are a young and NIH-funded lab, which is located near Los Angeles within the Beckman Research Institute of City of Hope. Our laboratory focuses on functional genomics in chronic lymphocytic leukemia (CLL) and systematically dissects genetic alterations contributing to the disease phenotype utilizing cutting-edge technologies including CRIPSR/Cas9 gene editing, single-cell sequencing, and integrated omics analysis (genomics, transcriptomics, and proteomics), coupling with murine models as well as clinical samples. The ultimate goal is to discover novel prognosis markers and design better therapeutic approaches for this heterogeneous disease. Candidates with strong background in RNA biology, cancer biology, and molecular biology are encouraged to apply.

Minimum Education and Skills Required for Consideration:

  • Ph.D., or M.D./Ph.D. degree in molecular and cancer biology, or a related discipline is required
  • Understanding fundamental mechanism of RNA biogenesis and oncogenesis, genomics and transcriptomic analysis is preferred
  • Familiar with flow cytometry and genetic murine models is preferred

The Beckman Research Institute of City of Hope is a world renowned institute with specific focus on the translational research. The Department of Systems Biology includes 13 research faculty and 80 postdoctoral fellows, staff scientists and research associates and is supported by an annual budget of $7 million in research grants from the National Institutes of Health (NIH), The Leukemia & Lymphoma Society, the Howard Hughes Medical Institute and the California Institute for Regenerative Medicine (CIRM).

For consideration, please directly send a CV, a brief statement of scientific research interests and start date availability to: lilwang@nullcoh.org. For detail laboratory information, please visit https://www.cityofhope.org/research/systems-biology/systems-biology-research-labs/lili-wang-lab.

 

Postdoctoral Fellow Position Available, Nelson Lau Lab, Dept of Biochemistry

https://www.bumc.bu.edu/biochemistry/profiles/nelson-lau/

The Nelson Lau lab in the Dept of Biochemistry is looking for a candidate with a PhD and prior molecular biology and biochemistry experience, a record of publications, and some proficiency with bioinformatics. Skills with Drosophila fly genetics or mosquitoes will also be highly considered. Genomics and deep sequencing experience will also be a plus.

Our group studies basic gene regulation mechanisms by small RNAs and the RNA interference pathway in animals. Specifically, we are interested in dissecting the molecular mechanisms of RNAi in the control of viruses and transposons during animal aging and brain function.

Candidates should send a CV, list of publications, and arrange for three recommendation letters to be sent to Nelson Lau: nclau@nullbu.edu.

Postdoctoral Position in RNA Biology of Stem Cells, Yale University

The Van Wolfswinkel Lab [www.vanwolfswinkellab.org] at Yale University is seeking a driven and creative postdoctoral associate to join our group. We are a young and collaborative NIH-funded lab that continues to develop innovative molecular approaches to address fundamental questions concerning stem cell health, regulation of cell fate, and cell population dynamics in their endogenous context. We are particularly interested in the molecular processes involved in the long-term maintenance of pluripotency and in the transition towards differentiation. Several lines of evidence have suggested important roles for non-coding RNAs (piRNAs and lncRNAs) and chromatin organization in these processes, and the planarian stem cell system is an excellent model to explore these further.

We are looking for a highly motivated molecular biologist with an interest in stem cell research and an inclination for technological development. Successful candidates have recently obtained a Ph.D. in a relevant field and should have experience with at least two of the following: biochemistry, RNA biology, chromatin biology, epigenetics and/or transcriptomics analysis. Excellent oral and written communication skills as well as strong problem solving skills are required.

The Van Wolfswinkel Lab is part of the department of Molecular Cellular and Developmental Biology, and forms a dynamic environment for scientific collaborations and growth. We are located on Science Hill, in close proximity to the other Yale science departments and many core facilities. Yale university offers a competitive salary and benefits package in a city with affordable living expenses. Conveniently located between Boston and New York, New Haven is the creative capital of Connecticut with cultural resources that include major museums, a critically-acclaimed repertory theater, state-of-the-art concert hall, and world-renowned schools of Architecture, Art, Drama, and Music.

To apply, please send a CV (including names and contact information of three references) and a cover letter explaining your experience and your motivation to Josien van Wolfswinkel (josien.van.wolfswinkel@nullyale.edu).

Postdoctoral Fellow, RNA Molecular Biology, Texas Medical Center, Houston Methodist Research Institute

JOB SUMMARY

Performs advanced research duties under the supervision/direction of a Principal Investigator.

This position is seeking a Postdoctoral Fellow (open rank) to work in an RNA molecular biology lab working on questions related to the molecular biology of cardiovascular disease and cancer. Prior RNA molecular biology experience is strongly preferred, with previous experience in ribosome profiling, qPCR, translational control, making stable clonal cell lines, and a detailed knowledge of translational control, RNA biochemistry or RNA processing (specifically alternative splicing and/or polyadenylation) steps all being particularly helpful.  This position will not involve work with animals, but may include the handling and processing of de-identified human samples from a tissue bank.

Candidates will have the opportunity to do both basic science and translational research as they work in a fast-paced and collaborative research environment in the heart of the Texas Medical Center at the Houston Methodist Research Institute.  They will learn and apply cutting edge methodologies to study how cytoplasmic capping and the FHIT tumor suppressor modulate the epitranscriptome and affect protein expression in cardiovascular disease and cancer in the lab of Dr. Daniel Kiss.  The Kiss lab is also associated with Houston Methodist Research Institute’s RNA Therapeutics Program which seeks to develop new RNA-based therapies for cancer and cardiovascular disease.

Excellent organization, communication and critical thinking skills, the ability to work both independently and in a team-based environment, plus self-motivation are prerequisites. Postdocs belonging to underrepresented groups, those with non-traditional career tracks, and those interested in eventually transitioning to industry positions are strongly encouraged to apply.  Postdocs with bioinformatics backgrounds looking to learn wet lab techniques are also encouraged to apply.  Your training will be tailored to you with an individual development plan (IDP) which will focus on aspects of research relevant to your long-term career goals (including those away from the bench).

If interested, please attach a letter of interest, curriculum vitae, a PDF of a recent publication, and a list of three references with your application. In your letter of interest, please describe your research background, how your previous research qualifies you for this opening, your contribution to your publication(s) and your future interests and career goals.

Email: dlkiss@nullhoustonmethodist.org

Start date: After June 1st, 2019

Duration : open, 2 year minimum commitment desired

Postdoctoral Fellow Position Available, Garvan Institute, Sydney, Australia

The Weatheritt lab is looking for a highly motivated candidate to investigate the role of alternative splicing in regulating phase transition and higher-order complex formation. The goal of the study is to characterise the regulatory potential of alternative splicing in the proteome. We are seeking highly motivated scientists with strong RNA, microscopy and molecular biology experience.

This is an EMBL Australia funded position located at the Garvan Institute in Sydney, Australia. Applicants should have a recent PhD in molecular biology or relevant field and have demonstrated research productivity through publications. Interested applicants should apply to r.weatheritt@nullgarvan.org.au by sending (i) a cover letter summarising research interests and accomplishments, (ii) a CV, and (iii) contact information for three references. Start date is flexible.

Postdoctoral Gellowship in Epigenetics and RNA Biology

Postdoctoral fellowship in epigenetics and RNA biology is available at the Department of Medical Biosciences and Wallenberg Centre for Molecular Medicine, Umeå University (Sweden)

A funded postdoctoral position (2 years) is available in the Aguilo (www.aguilolab.com) and Lundin laboratories at Umeå University for a highly talented and motivated candidate willing to address fundamental questions in post-transcriptional regulation of RNA in connection with epigenetic regulation in gynaecological cancers.

Project description

The aim is to investigate the functional importance of N6-methyladenosine (m6A) RNA modification in tumorigenesis, tumor progression, and metastasis with a first focus on gynecological cancer, and a long-term goal of expanding our study to common cancers, including prostate, renal, colorectal, and pancreatic cancer.

Application

The application should include the following:

  • A cover letter (max two A4 pages) with a summary of research interests and accomplishments
  • Curriculum vitae (CV)
  • Copies of relevant degree certificates and PhD thesis
  • Contact information (name, address, telephone and e-mail) for three referees

Your complete application should be sent electronically (PDF format) to Dr. Francesca Aguilo francesca.aguilo@nullumu.se with subject POSTDOC_2019 no later than 1st of May, 2019