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Postdoctoral Position in RNA Biology of Stem Cells, Yale University

The Van Wolfswinkel Lab [www.vanwolfswinkellab.org] at Yale University is seeking a driven and creative postdoctoral associate to join our group. We are a young and collaborative NIH-funded lab that continues to develop innovative molecular approaches to address fundamental questions concerning stem cell health, regulation of cell fate, and cell population dynamics in their endogenous context. We are particularly interested in the molecular processes involved in the long-term maintenance of pluripotency and in the transition towards differentiation. Several lines of evidence have suggested important roles for non-coding RNAs (piRNAs and lncRNAs) and chromatin organization in these processes, and the planarian stem cell system is an excellent model to explore these further.

We are looking for a highly motivated molecular biologist with an interest in stem cell research and an inclination for technological development. Successful candidates have recently obtained a Ph.D. in a relevant field and should have experience with at least two of the following: biochemistry, RNA biology, chromatin biology, epigenetics and/or transcriptomics analysis. Excellent oral and written communication skills as well as strong problem solving skills are required.

The Van Wolfswinkel Lab is part of the department of Molecular Cellular and Developmental Biology, and forms a dynamic environment for scientific collaborations and growth. We are located on Science Hill, in close proximity to the other Yale science departments and many core facilities. Yale university offers a competitive salary and benefits package in a city with affordable living expenses. Conveniently located between Boston and New York, New Haven is the creative capital of Connecticut with cultural resources that include major museums, a critically-acclaimed repertory theater, state-of-the-art concert hall, and world-renowned schools of Architecture, Art, Drama, and Music.

To apply, please send a CV (including names and contact information of three references) and a cover letter explaining your experience and your motivation to Josien van Wolfswinkel (josien.van.wolfswinkel@nullyale.edu).

Postdoctoral Fellow, RNA Molecular Biology, Texas Medical Center, Houston Methodist Research Institute

JOB SUMMARY

Performs advanced research duties under the supervision/direction of a Principal Investigator.

This position is seeking a Postdoctoral Fellow (open rank) to work in an RNA molecular biology lab working on questions related to the molecular biology of cardiovascular disease and cancer. Prior RNA molecular biology experience is strongly preferred, with previous experience in ribosome profiling, qPCR, translational control, making stable clonal cell lines, and a detailed knowledge of translational control, RNA biochemistry or RNA processing (specifically alternative splicing and/or polyadenylation) steps all being particularly helpful.  This position will not involve work with animals, but may include the handling and processing of de-identified human samples from a tissue bank.

Candidates will have the opportunity to do both basic science and translational research as they work in a fast-paced and collaborative research environment in the heart of the Texas Medical Center at the Houston Methodist Research Institute.  They will learn and apply cutting edge methodologies to study how cytoplasmic capping and the FHIT tumor suppressor modulate the epitranscriptome and affect protein expression in cardiovascular disease and cancer in the lab of Dr. Daniel Kiss.  The Kiss lab is also associated with Houston Methodist Research Institute’s RNA Therapeutics Program which seeks to develop new RNA-based therapies for cancer and cardiovascular disease.

Excellent organization, communication and critical thinking skills, the ability to work both independently and in a team-based environment, plus self-motivation are prerequisites. Postdocs belonging to underrepresented groups, those with non-traditional career tracks, and those interested in eventually transitioning to industry positions are strongly encouraged to apply.  Postdocs with bioinformatics backgrounds looking to learn wet lab techniques are also encouraged to apply.  Your training will be tailored to you with an individual development plan (IDP) which will focus on aspects of research relevant to your long-term career goals (including those away from the bench).

If interested, please attach a letter of interest, curriculum vitae, a PDF of a recent publication, and a list of three references with your application. In your letter of interest, please describe your research background, how your previous research qualifies you for this opening, your contribution to your publication(s) and your future interests and career goals.

Email: dlkiss@nullhoustonmethodist.org

Start date: After June 1st, 2019

Duration : open, 2 year minimum commitment desired

Postdoctoral Fellow Position Available, Garvan Institute, Sydney, Australia

The Weatheritt lab is looking for a highly motivated candidate to investigate the role of alternative splicing in regulating phase transition and higher-order complex formation. The goal of the study is to characterise the regulatory potential of alternative splicing in the proteome. We are seeking highly motivated scientists with strong RNA, microscopy and molecular biology experience.

This is an EMBL Australia funded position located at the Garvan Institute in Sydney, Australia. Applicants should have a recent PhD in molecular biology or relevant field and have demonstrated research productivity through publications. Interested applicants should apply to r.weatheritt@nullgarvan.org.au by sending (i) a cover letter summarising research interests and accomplishments, (ii) a CV, and (iii) contact information for three references. Start date is flexible.

Postdoctoral Gellowship in Epigenetics and RNA Biology

Postdoctoral fellowship in epigenetics and RNA biology is available at the Department of Medical Biosciences and Wallenberg Centre for Molecular Medicine, Umeå University (Sweden)

A funded postdoctoral position (2 years) is available in the Aguilo (www.aguilolab.com) and Lundin laboratories at Umeå University for a highly talented and motivated candidate willing to address fundamental questions in post-transcriptional regulation of RNA in connection with epigenetic regulation in gynaecological cancers.

Project description

The aim is to investigate the functional importance of N6-methyladenosine (m6A) RNA modification in tumorigenesis, tumor progression, and metastasis with a first focus on gynecological cancer, and a long-term goal of expanding our study to common cancers, including prostate, renal, colorectal, and pancreatic cancer.

Application

The application should include the following:

  • A cover letter (max two A4 pages) with a summary of research interests and accomplishments
  • Curriculum vitae (CV)
  • Copies of relevant degree certificates and PhD thesis
  • Contact information (name, address, telephone and e-mail) for three referees

Your complete application should be sent electronically (PDF format) to Dr. Francesca Aguilo francesca.aguilo@nullumu.se with subject POSTDOC_2019 no later than 1st of May, 2019

 

 

Postdoc Position: Molecular Biology of CRISPR-Cas9 and Long Noncoding RNAs

Are you a molecular biologist who loves the challenge of developing new methods?

Then the “Genomics of Long Non-Coding RNAs in Disease” Laboratory (GOLD Lab) has an opportunity for you!

The Project: Understanding how long noncoding RNA (lncRNA) functions are encoded in their sequence is a great challenge in biology. Our goal is to discover, classify and characterise lncRNA functional elements by means of an integrative bioinformatic / experimental approach. You will lead an experimental project to develop novel methods, based on CRISPR-Cas9, to dissect lncRNA functionality. Work will benefit from close collaboration with our team of experimentalists and computer scientists with wide experience in genome engineering.

The Group: We are a diverse and interdisciplinary team of researchers with a passion for lncRNA research. We foster an open and collaborative working environment. Our work is funded by the Swiss National Center for Competence in Research (NCCR) “RNA & Disease” (nccr-rna-and-disease.ch) project, providing numerous links with other RNA researchers. We also participate in GENCODE and the International Cancer Genome Consortium (ICGC). We enjoy clinical collaborations at the University Hospital of Bern. For more information about us see gold-lab.org and twitter.com/goldlab_bern.

The City: Bern, the capital of Switzerland, is well connected at the heart of Europe, has a vibrant international community, numerous outdoors and cultural activities, and ranks among the best cities worldwide for quality of life (https://tinyurl.com/y9vrtb7d).

The Person: We seek a dedicated and dynamic colleague to integrate into our team. The project will be strongly focused on developing new CRISPR-Cas9 techniques, so you should have solid experience in some of: molecular biology, CRISPR-Cas9, RNA biology, method development, innovative solutions.

Details: Ideal start date will be Q1 of 2019. Project is fully funded for at least 3 years. Salary is according to (generous) University of Bern scales.

Recent publications:

Esposito et al Cancer Cell. 2019 Feb 14. pii: S1535-6108(19)30053-4.

Carlevaro-Fita et al. Genome Res. 2019 Feb;29(2):208-222.

Uszczynska-Ratajczak B et al. Nat Rev Genet. 2018 Sep;19(9):535-548. doi: 10.1038/s41576-018-0017-y.

Lagarde J et al. Nat Genet. 2017 Dec;49(12):1731-1740. doi: 10.1038/ng.3988.

To apply: Please send a brief email explaining how you fit the project description, publications list, and CV to rory.johnson[at]dbmr.unibe.ch with subject title: “Job application SNF Postdoc”. Informal enquiries are also welcome. The position will be advertised until filled, and latest updates on the job availability will be posted at www.gold-lab.org/we-are-hiring, so please check before applying

18-month Post-Doctoral Position Available Immediately at the University of Edinburgh

An 18-month post-doctoral position is available immediately at the University of Edinburgh to establish whether mammalian RNA-binding proteins (approx. 1500 in human) can be regulated via “histone-code” like switches, where specific lysine modification regulates competing protein-protein interactions. Such a switch would provide unique insight into the basis of the multi-functionality of many RNA-binding proteins. This BBSRC funded work builds upon work by three collaborating Edinburgh labs (Matt Brook’s newly-formed lab [Twitter: @BrookLab3] and the established labs of Nicola Gray and Atlanta Cook) and involves collaborating labs in Liverpool, Dundee and Birmingham. The post-holder will determine the modification-dependent effects on post-transcriptional gene regulation (mRNA translation and stability), primarily through mammalian cell line-based and/or cell-free reporter assays, quantify modification stoichiometry under specific cellular conditions and investigate the effector enzymes involved. They will work closely with another post-doctoral scientist who focuses on the biophysical and structural consequences of these modifications on protein-protein interactions. Applicants with a proven track record in studying RNA-binding protein-mediated regulation of mRNA translation and stability, and/or the interrogation of lysine acetylation/methylation pathways are particularly welcomed. The post is particularly suitable for candidates with relevant post-doctoral experience but those with strong, relevant, publication records from their PhD would also be considered. The post involves short periods of work at other locations (e.g. Liverpool) leveraging specialised collaborative expertise/training (e.g. quantitative mass spectrometry).

For full details of the vacancy and to apply, please visit: https://www.vacancies.ed.ac.uk/pls/corehrrecruit/erq_jobspec_version_4.display_form

Postdoctoral position available at University of Helsinki/Laboratory of Dr. Mikko Frilander

Frilander laboratory at the Institute of Biotechnology/University of Helsinki, Finland, is looking for a post-doctoral researcher in a project that investigates the regulation of pre-mRNA processing by the minor spliceosome during cellular differentiation and human diseases linked to minor spliceosome.

We are particularly interested in individuals with strong background either in bioinformatics or molecular biology/cell biology in RNA-related research topic. Applicant should have a PhD in bioinformatics, molecular biology or in a related field, and at least one first author publication.

The fully funded position is initially available for 2-3 years, depending on the start date. For further information and application form, please visit group web pages: www.helsinki.fi/minor-spliceosome

The deadline for applications is March 25, or until the position has been filled.

Postdoctoral fellowship in epigenetics and RNA biology at the Department of Medical Biosciences and Wallenberg Centre for Molecular Medicine, Umeå University (Sweden)

A funded postdoctoral position (2 years) is available in the Aguilo (www.aguilolab.com) and Lundin laboratories at Umeå University for a highly talented and motivated candidate willing to address fundamental questions in post-transcriptional regulation of RNA in connection with epigenetic regulation in gynaecological cancers.

Project description
The aim is to investigate the functional importance of N6-methyladenosine (m6A) RNA modification in tumorigenesis, tumor progression, and metastasis with a first focus on gynecological cancer, and a long-term goal of expanding our study to common cancers, including prostate, renal, colorectal, and pancreatic cancer.

Application
The application should include the following:
• A cover letter (max two A4 pages) with a summary of research interests and accomplishments
• Curriculum vitae (CV)
• Copies of relevant degree certificates and PhD thesis
• Contact information (name, address, telephone and e-mail) for three referees

Your complete application should be sent electronically (PDF format) to Dr. Francesca Aguilo francesca.aguilo@nullumu.se with subject POSTDOC_2019 no later than 1st of May, 2019

Postdoctoral Associate Position Immediately Available, RNA biology, Penn State University

A postdoctoral associate position is immediately available in the lab of Dr. Reyad Elbarbary at the College of Medicine, Penn State University.

Dr. Elbarbary’s lab combines basic RNA biology and translational musculoskeletal research (relevant publications include Elbarbary et al. Science 2017, Elbarbary et al. Genes Dev 2017, Elbarbary et al. Genes Dev 2013, Le Bleu et al. Anal Biochem 2017).

The lab’s primary focus is to identify the molecular basis of obesity/type 2 diabetes-associated bone diseases and to establish the varied and critical roles of non-coding RNA in bone homeostasis.

Research in Dr. Elbarbary’s lab utilizes cell culture, mouse models, and human clinical samples.  The lab employs a wide array of experimental approaches that include real-time PCR, RNA-seq, miR-seq, immunofluorescence, confocal microscopy, CLIP, RIP, mass spectrometry, DEXA scan, micro-CT, osteomorphometry, and nanoparticle-mediated drug delivery.

We are seeking a creative, career-driven candidate to join our group. Candidates must hold a PhD. A Strong publication record and significant experimental training in RNA biology, biochemistry, bioinformatics, or cell biology are required. Experience in bone biology or mouse models is a plus.

Dr. Elbarbary’s lab is a part of the newly established Center for Orthopaedic Research and Translational Science (CORTS) in Penn State College of Medicine. The successful candidate will benefit from the collaborative scientific environment in CORTS as well as the technical expertise of its members.

Interested candidates should email a cover letter, a current CV, a brief personal statement, and the contacts of three references to Dr. Reyad Elbarbary (relbarbary@nullpennstatehealth.psu.edu).

CAMPUS SECURITY CRIME STATISTICS: For more about safety at Penn State, and to review the Annual Security Report which contains information about crime statistics and other safety and security matters, please go to  http://www.police.psu.edu/clery/, which will also provide you with detail on how to request a hard copy of the Annual Security Report.

Penn State is an equal opportunity, affirmative action employer, and is committed to providing employment opportunities to all qualified applicants without regard to race, color, religion, age, sex, sexual orientation, gender identity, national origin, disability or protected veteran status.

 

Two Doctoral Student Positions Available, Sattler lab, Munich, Germany

Two doctoral student positions are available in frame of the EU HORIZON 2020 MSC-ITN project RNAct in the Sattler lab, Munich.

Integrative structural biology and biophysics to analyze and design RNA interactions of RNA-Recognition Motif (RRM) proteins

The RNAct network is highly interdisciplinary and combines molecular biology and recombinant protein expression with advanced techniques in structural biology focusing on solution NMR and crystallography. Some experimental experience in these techniques is very desirable. Candidates must be highly motivated and interested in interdisciplinary research and developing new ideas. Candidates must be fluent in English.

Further information: http://rnact.eu.
Application deadline: March 15, 2019

ESR5 project: RRM structure and design for synthetic biology and bio-analytics applications.

ESR6 project: Conformational dynamics and RNA binding specificity of RRMs using integrative structural biology and biophysics

We offer outstanding facilities for NMR (http://www.bnmrz.org) with various high-field NMR spectrometers (including 950, 900, 800 MHz, 1.2 GHz pending), crystallography, small angle scattering (in-house SAXS) and access to synchrotron beamtime, as well as a new state-of-the-art biochemical lab facilities.

Eligibility:

European funding require an international mobility:  The candidates must not have resided or carried out their main activity in Germany for more than 24 months in the 3 years prior to the recruitment. Candidates must have a master degree relevant disciplines: (bio-)physics, structural biology, biochemistry, chemistry.

 

Scientist – RNA Biology, Eclipse BioInnovations Inc., San Diego CA

Eclipse BioInnovations Inc. is a leading RNA NGS company in San Diego looking to add
dynamic and talented people to our growing team. Our mission is to use our first-in-class
Eclipse-Seq RNA NGS platform technologies to accelerate the creation and development
of truly safe and effective RNA medicines. As a small company, each member of our
team plays a key role and will be expected to make a significant contribution to the
growth and success of Eclipse.

We are seeking highly motivated scientists with strong RNA and molecular biology
experience to support our rapidly growing RNA NGS research service and kit business.

Eclipse Job Posting SCI-2019-012
Scientist – RNA Biology

Job Description:
• Direct, plan, execute and analyze eCLIP and other RNA/NGS sample prep
experiments for customer and internal projects as required without minimal manager
supervision, utilizing standard biochemical and molecular techniques

• Development, characterization and optimization of existing assays as well as novel
methods, technologies and products

• Examine data and preparation of technical reports, summaries, protocols and
quantitative analysis and ensuring experiments are well documented

• Tracking, reporting and customer relations for ongoing service contracts

• General lab tasks including ordering, organizing, and instrument maintenance
Requirements

• Candidate must have hands-on experience with standard biochemical and molecular
biological procedures, with a particular emphasis on strong RNA isolation and handling
experience, as well as western analysis, qPCR, transfection and gel electrophoresis

• PhD in Cell Biology, Molecular Biology or related discipline with 2-5 years
experience in an R&D laboratory

• Excellent written and oral communication skills

• Attention to detail, proficient reasoning skills in experimental design, data analysis,
statistical methods and experimental interpretation, resourcefulness and the ability to
work independently in a fast paced team environment

Preference will be given to candidates with:

• hands-on experience in high-throughput sequencing library preparation

• industry experience

• Ability to run command-line analysis tools for basic data analysis

We offer competitive salary commensurate with candidate’s experience, and an excellent
benefits package including medical, dental, vision and paid time leave.
Please apply to jobs@nulleclisebio.com with SCI-2019-012 in the subject line.

Eclipse BioInnovations Inc., Research Associate/Senior Research Associate Scientist – RNA Biology

Eclipse BioInnovations Inc. is a leading RNA NGS company in San Diego looking to add
dynamic and talented people to our growing team. Our mission is to use our first-in-class
Eclipse-Seq RNA NGS platform technologies to accelerate the creation and development
of truly safe and effective RNA medicines. As a small company, each member of our
team plays a key role and will be expected to make a significant contribution to the
growth and success of Eclipse.

We are seeking highly motivated scientists with strong RNA and molecular biology
experience to support our rapidly growing RNA NGS research service and kit business.

Eclipse Job Posting RA-2019-011
Research Associate / Senior Research Associate Scientist – RNA Biology

Job Description:

• Plan, execute and analyze eCLIP and other RNA/NGS sample prep experiments
under manager supervision, utilizing standard biochemical and molecular techniques

• Examine data and preparation of technical reports, summaries, protocols and
quantitative analysis and ensuring experiments are well documented

• Tracking, reporting and customer relations for ongoing service contracts

• Development, characterization and optimization of assay protocols and reagents

• General lab tasks including ordering, organizing, and instrument maintenance
Requirements

• Candidate must have hands-on experience with standard biochemical and molecular
biological procedures, with a particular emphasis on strong RNA isolation and handling
experience, as well as western analysis, qPCR, transfection and gel electrophoresis

• BS/MS in Molecular / Cell Biology or related discipline with 2-6 years experience
in an R&D laboratory

• Excellent written and oral communication skills

• Attention to detail, proficient reasoning skills in experimental design, data analysis,
statistical methods and experimental interpretation, resourcefulness and the ability to
work independently in a fast paced team environment

Preference will be given to candidates with:

• Hands-on experience in high-throughput sequencing library preparation

• Ability to run command-line analysis tools for basic data analysis

• Experience with life science tools and reagents product development or marketing

• Industry experience

We offer competitive salary commensurate with candidate’s experience, and an excellent
benefits package including medical, dental, vision and paid time leave.
Please apply to jobs@nulleclipsebio.com with Eclipse RA-2019-011 in the subject line.

Ph.D. Program, University of Evry (France)

Ph.D. program: “Splice site recognition mechanisms and regulators”

The University of Evry (South suburb of Paris France) is seeking for a candidate to a Ph.D. program focused on functional analyses of splicing regulators. The successful candidate will be hosted by the SABNP laboratory which is dedicated at studying networks of RNA binding proteins using integrative approaches combining biochemical, structural and functional analyses.

Scientific project: Defects in constitutive or alternative pre-mRNA splicing have dramatic consequences on protein expression. Indeed genetic diseases are often associated with mutations of RNA sequences recognized by splicing factors or by mutations or abnormal expression of spliceosomal RNA-Binding Proteins (RBPs). However a detailed knowledge of the  mechanisms that allow the precise recognition of splice sites is still lacking.

The Ph.D. student will combine bioinformatics analyses of splicing factors related datasets with biochemical and functional analyses to unravel novel aspects of their mode of action. In particular the cooperative or antagonistic functions of these splicing factors will be searched for by correlation analyses in RNA-seq datasets and the corresponding physical interactions will be determined using biochemical techniques and in vivo. The sequences targeted by these splicing factors will be evaluated and tested in vivo. Finally their relationship to cancer, neurodevelopmental syndromes and neurodegenerative diseases will be tackled.

Keywords : pre-mRNA splicing, splice site recognition, RNA Binding Proteins, U2AF related proteins, genetic diseases, cancer.

Host laboratory and context:

The successful candidate will be funded by the University of Evry and will perform his research in the SABNP laboratory (INSERM research unit UMR1204) at Evry University, part of the Genopole biocluster for biotechnologies.

Based on a multidisciplinary approach, the SABNP laboratory notably explores the dynamics and structure of RNA/protein complexes. Novel technologies are also currently developed to explore cellular and molecular processes involved in gene expression regulation.

Candidate profile: Candidates must hold a master degree (or equivalent) in cellular biology, molecular biology or bioinformatics and be highly motivated individuals with interest in RNA biology, gene expression and data processing.

Contact and application: For further information, please contact Alexandre Maucuer at alexandre.maucuer@nullinserm.fr . For application, please provide a full CV, a cover letter and a copy of the grades obtained during the master degree.

Position open until: 04/30/2019

Email: alexandre.maucuer@nullinserm.fr   

Post-doctoral Position Available, Virginia Tech

Post-doctoral position to study the functions of a novel non-coding RNA in the mammalian circadian clock system (Virginia Tech)

The Kojima Lab is looking for a highly motivated Postdoctoral Associate to work on an exciting project that dissects molecular mechanisms underlying mammalian circadian rhythms. The NIH-funded new project will address the functions of a novel non-coding gene using a combination of molecular/cellular biology, bioinformatics and mathematical models. We are looking for ambitious, creative and smart colleagues, whose expertise enriches our team.

Required Qualifications include: 1) Ph.D. degree in biochemistry, biology, or a related field, 2) One or more publication as a first-author in a peer-reviewed journal, 3) Experience in at least one of the following fields (molecular/cellular biology, generation of genetically modified animal models, RNA biology). Experiences in bioinformatics and/or mathematical modeling of molecular regulatory networks will be appreciated.

This positions carry a salary of $45,000 – $58,850 (depending on experience) plus benefits, including health insurance. Review of applications will begin immediately until the positions are filled. To apply, please submit a cover letter discussing your interest in a position, your curriculum vitae, a half-page research statement, and contact information for three references at: https://listings.jobs.vt.edu/postings/94635

Further inquiries should be directed to Shihoko Kojima (skojima@nullvt.edu). Our laboratory is committed to promoting diversity and inclusion at Virginia Tech, and we welcome applications by individuals with disabilities, or members of minorities or other disadvantaged groups.

Postdoctoral Position Available, RNA Chemical Biology, Lab of Prof. Ralph Kleiner, Princeton University

A postdoctoral position in RNA Chemical Biology is available in the lab of Professor Ralph Kleiner at Princeton University.

A PhD in Chemistry, Biology or a related field is required. Candidates with expertise in any of the following areas are encouraged to apply: nucleic acid chemistry, RNA biochemistry, protein biochemistry, bioinformatics, and cell biology.

The start date for the position is negotiable. Please send applications containing your CV, cover letter, and a list of 3 references to rkleiner@nullprinceton.edu.

Three Post-Doctoral Positions To Study Mechanisms Of Translation And Translation-Associated Quality Control Processes In Eukaryotes

Three postdoctoral research positions are open in the laboratories of Tatyana Pestova and Christopher Hellen at the State University of New York Downstate Medical Center in Brooklyn, NY, USA. Our NIH-funded research uses state-of-art biochemical and molecular biology approaches to characterize molecular mechanisms of (1) canonical and non-canonical modes of translation initiation in mammals, including IRES-mediated initiation, (2) physiologically important specific cases of translational regulation, (3) translation elongation, termination and ribosome recycling, and (4) events downstream of termination, with a major focus on quality control processes, including mRNA surveillance and ribosome-associated quality control.

Required qualifications include a Ph.D. in Molecular Biology/Molecular Biochemistry, and practical experience in RNA and/or protein biochemistry, including the expression and purification of native/recombinant proteins and the functional analysis of proteins and RNA-protein complexes. Experience in investigating aspects of eukaryotic translation and associated quality control processes will be highly appreciated. Our research involves active collaborations with leading cryoEM laboratories, and experience in structural biology would therefore be helpful.  Candidates should be highly motivated, be able to work independently and show excellent critical thinking, scholarly ability and communication skills.

These positions carry a salary of $45,000 – $60,000 (depending on experience) plus benefits, including health insurance. Review of applications will begin immediately until the positions are filled. To apply, please send a cover letter discussing your interest in a position and mentioning the expected availability date, your curriculum vitae (including a summary of research experience, including techniques and methods used, and a list of publications) and contact information for three references to:

christopher.hellen@nulldownstate.edu
or
Tatyana.pestova@nulldownstate.edu

As an Equal Opportunity / Affirmative Action employer, the Research Foundation will not discriminate in its employment practices due to an applicant’s race, color, religion, sex, national origin and veteran or disability status. Personnel are chosen on the basis of ability without regard to Race, Color, Religion, Sex, Age, National Origin, Disability or Marital Status in Accordance with Federal and State Law.

Postdoctoral Researcher Position Available Immediately, Laboratory of Dr. Mingyi Xie

Postdoctoral Researcher position available immediately in the Laboratory of Dr. Mingyi Xie (Assistant Professor, Department of Biochemistry and Molecular Biology,

Cancer Center, University of Florida) to study the Function and biogenesis of alternatively-processed microRNAs and Integrator complex-mediated RNA processing. Postdoc salary starts at $47,476 per year.

Applicants should submit the following to mingyi.xie@nullufl.edu:

1)      Cover letter stating: laboratory experience in RNA/protein biochemistry and/or bioinformatics; your long-term career goals; date of availability to begin postdoc research

2)      Curriculum vitae (including publications and awards/honors)

3)      List of at least three references

Visit Xie lab website: xie.biochem.med.ufl.edu for more information.

Postdoctoral Fellow Positions Available, Lab of Dan Herschlag

The laboratory of Dan Herschlag (herschlaglab.stanford.edu) is looking for motivated,
creative and interactive candidates in the following areas:
• RNA tertiary folding: We have developed an RNA Reconstitution Model as a
conceptual framework that can in principle provide quantitative predictions of RNA
folding stability and rates. Continued high-throughput thermodynamic measurements
with the Greenleaf lab (Stanford) will provide the foundation for determining the
conformational landscapes, or ensembles, for individual RNA motifs that can be
combined to predict the folding properties of complex RNAs and RNA/protein
complexes.
(See DOI: 10.1016/j.cell.2018.05.038 and DOI: 10.1101/cshperspect.a032433)
• RNA/protein interactions: Using the Greenleaf platform, we have for the first time
obtained a fully predictive model for RNA/protein binding. We are interested in
deepening our understanding of RNA/protein recognition and in applying this model to
identify and quantitate the cellular features that determine RNA/protein interactions in
vivo using Quantitative Cellular Biochemistry, which entails parallel high-throughput
quantitative measurements in vitro and in cells.
(See DOI: http://dx.doi.org/10.1101/403006)
The lab provides an excellent training environment and is located in a highly
collaborative and interdisciplinary environment at Stanford. Salary is adjusted for
California’s cost of living. To apply, please send (1) a cover letter, with your specific
research interests in relation to the above project and broader lab research, as well as your
training and career goals; (2) C.V.; and (3) names and contact information of three
references to Morgan Williams (mwillia@nullstanford.edu).

Postdoctoral Fellow Position Available, University Of Rochester School Of Medicine

The Ermolenko lab at the University Of Rochester School Of Medicine (https://www.urmc.rochester.edu/labs/ermolenko.aspx)  is looking for a postdoctoral fellow to study the role of the intrinsic closeness of mRNA ends in protein synthesis (please see our recent publication on this topic https://www.nature.com/articles/s41467-018-06792-z). We use biochemical approaches and single-molecule fluorescent microscopy. The position is immediately available and will remain open until filled. Applicants with recent PhD in biochemistry or molecular biology are invited to email their CV and cover letter to Dmitri_Ermolenko@nullURMC.Rochester.edu.

Post Doctoral Position Available, Vinther Lab, Dept of Biology, University of Copenhagen

A 12 months postdoc position (with the possibility of extension) is available at Vinther Lab, Department of Biology, University of Copenhagen. The position will be available as of 1 May 2019.

The project is focused on the analysis of the consequences of oxidative signaling and damage on the transcriptome. The postdoc will be responsible for performing sequencing based experiments to map and analyse oxidation of specific RNA positions using cell culture model systems and sequencing based mutational profiling.

The Vinther Lab has extensive experimental and computational knowhow related to implementation of sequencing based methods and the analysis of the data. We maintain an informal, collaborative and productive working environment at the interface of experimental RNA biology and Bioinformatics. Recent publications by the Vinther Lab: PMID 29126318 26220183, 25805860, 24569351.

Qualifications:

I am looking for highly motivated individuals with a PhD degree. Candidates with some experience with massive parallel sequencing based experiments, Iron Biology, Reactive Oxygen Species or RNA Biology/Biochemistry will be preferred.

For consideration, applicants must:

  • Have a PhD in molecular biology, biochemistry, medicine or a similar field
  • Have published in international peer-reviewed journals

The working language is English, thus excellent English speaking, reading and writing skills are required.

For further information about the position, please contact Associate Professor Jeppe Vinther (jvinther@nullbio.ku.dk). The application deadline is February 15, 2019. To apply for the position use this link: https://candidate.hr-manager.net/ApplicationInit.aspx?cid=1307&ProjectId=148642&DepartmentId=18965&MediaId=4636&SkipAdvertisement=true