Employment Opportunities

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Postdoctoral Associate Position Immediately Available in Penn State University College Of Medicine (PSUCOM)

A postdoctoral associate position is immediately available in the laboratory of Dr. Reyad Elbarbary (Assistant Professor at the Department of Orthopaedics and Rehabilitations and the Department of Biochemistry and Molecular Biology, College of Medicine, Penn State University).

Dr. Elbarbary’s lab combines basic RNA biology and translational musculoskeletal research (relevant publications include Elbarbary et al. Science 2017, Elbarbary et al. Genes Dev 2017, Elbarbary et al. Genes Dev 2013, Le Bleu et al. Anal Biochem 2017). The lab’s primary focus is to establish the varied and critical roles of:

1) Non-coding RNA in bone and cartilage tissue homeostasis and disease

2) Retrotransposons in osteoarthritis for development of chondroregenerative therapeutic approaches

Research in Dr. Elbarbary’s lab utilizes cell culture, mouse models, and human clinical samples.  The lab employs a wide array of experimental approaches that include real-time PCR, RNA-seq, miR-seq, immunofluorescence, confocal microscopy, CLIP, RIP, mass spectrometry, DEXA scan, micro-CT, osteomorphometry, functional analyses of muscle strength and gait, and nanoparticle-mediated drug delivery.

We are seeking a creative, career-driven candidate to join our group. Candidates must hold a PhD. A Strong publication record and significant experimental training in bone biology are required, and expertise in RNA biology is a plus.

Dr. Elbarbary’s lab is a part of the newly established Center for Orthopaedic Research and Translational Science (CORTS) in PSUCOM. The successful candidate will benefit from the collaborative scientific environment in CORTS as well as the technical expertise of its members.

Interested candidates should email a cover letter, a current CV, a brief personal statement, and the contacts of three references to Dr. Reyad Elbarbary (relbarbary@nullpennstatehealth.psu.edu).

CAMPUS SECURITY CRIME STATISTICS: For more about safety at Penn State, and to review the Annual Security Report which contains information about crime statistics and other safety and security matters, please go to  http://www.police.psu.edu/clery/, which will also provide you with detail on how to request a hard copy of the Annual Security Report.

Penn State is an equal opportunity, affirmative action employer, and is committed to providing employment opportunities to all qualified applicants without regard to race, color, religion, age, sex, sexual orientation, gender identity, national origin, disability or protected veteran status.

 

Postdoctoral Position to study RNA-Guided Genome Rearrangements at Columbia University in the City of New York

Postdoctoral Research positions are available in our newly renovated lab overlooking the Hudson River in the Department of Biochemistry and Molecular Biophysics, with a research focus on Non-Coding RNA-Mediated Genome Rearrangement, Editing, Epigenetics, Chromatin, Genome Evolution, and Transposon Involvement.

Laura Landweber is seeking to hire postdoctoral researchers to study the mechanism of gene and genome unscrambling in the ciliate Oxytricha, particularly the role of non-coding RNAs in this process.

Requirements: PhD in molecular biology or relevant field. Strong experimental training, experience, and publications from the Ph.D., ability to work independently and creatively, as well as collaboratively and strong research and written/oral communication skills are necessary.

This is a one-year initial appointment with opportunity for renewal. Funding is available for longer. Please email Laura.Landweber@nullcolumbia.edu to apply. Include a cover letter, CV, statement of research interests and email addresses for three references. Application review will begin immediately; start date is flexible.

The Landweber lab has a strong commitment to diversity and to supporting its students, postdocs, and alumni at all career stages. Many lab alumni have received tenure in academic positions (10) or chosen other successful options. Conference participation is encouraged throughout the postdoc period, as part of training for a scientific career.

The Landweber lab is located at Columbia University Medical Center in the Department of Biochemistry & Molecular Biophysics, with joint appointments in Systems Biology and Biological Sciences on the Arts & Sciences campus. Housing assistance is available.

biology.columbia.edu/people/landweber

Columbia University Medical Center: Faculty Positions in RNA Biology & Chromosome Structure and Function Department of Biochemistry and Molecular Biophysics

The Department of Biochemistry and Molecular Biophysics at Columbia’s College of Physicians and Surgeons invites outstanding candidates to apply for TENURE-TRACK faculty positions at the level of Assistant Professor. The department seeks individuals with exceptional accomplishments and abilities in the broad areas of RNA and chromatin biology. Examples include, but are not limited to: RNA splicing, non-coding RNA structure and function, biophysics and evolution of RNA; phase transition and RNA granules; RNA interactions with DNA and chromatin; single molecule live imaging, chromatin dynamics, and nuclear organization.  We seek colleagues committed to scientific excellence, diversity, and collegiality.

Applicants should provide a summary of their scientific accomplishments, and a description of their scientific vision, emphasizing one or more major unsolved problems in their field and how they plan to solve them (no more than three pages).

The department of Biochemistry and Molecular Biophysics offers a rigorous and stimulating environment for conducting research. Faculty use the full spectrum of contemporary biophysical, biochemical, molecular biological, and cellular techniques to study developmental biology; gene expression, regulation and signal transduction; macromolecular structure, function and dynamics; and molecular neurobiology. The Department has a rich history of excellence in molecular and structural biology and molecular neuroscience.

Essential Qualifications

All applicants must have a Ph.D., M.D., or equivalent degree. In addition, applicants must have a very strong record of research productivity and demonstrated ability to develop a rigorous research program.

Completed applications, including the research statement, curriculum vitae, PDF copies or links for three reprints, and contact information for three references must be submitted online via the following website:

academicjobs.columbia.edu/applicants/Central?quickFind=64947

Consideration of completed applications will begin immediately and continue until the positions are filled.

Columbia University is an equal opportunity/affirmative action employer. Women and minorities are especially encouraged to apply.

Postdoctoral Scholar Position, Laboratory of Dr. Ruslan Afasizhev, Department of Molecular and Cell Biology, Boston University Medical Campus

Postdoctoral Scholar position is available in the laboratory of Dr. Ruslan Afasizhev at the Department of Molecular and Cell Biology, Boston University Medical Campus.

Our NIH-funded program focuses on the mechanisms of RNA processing in trypanosomes. Current projects cover mitochondrial transcription, mRNA editing, mRNA stability, translation and small RNAs biogenesis.

For more details, please see recent publications listed below. Our collaborations extend into structural biology, mass spectrometry, drug design and bioinformatics.

Required qualifications include strong background in molecular biology and biochemistry, and a record of peer-reviewed publications. Experience in RNAi, bioinformatics, RNA-Seq, ribosome profiling, protein purification, mass spectrometry and parasite genetics is desirable, but not required.

This position carries a starting salary of $45,000 for a junior candidate, or commensurate with experience, plus health benefits. Funding will be provided for up to three years although fellowship applications are encouraged.

Boston University Medical Campus is located in the vibrant South End area of Boston and offers a highly collaborative environment, unlimited networking possibilities in a thriving biomedical community, excellent core facilities and outstanding cultural and recreational opportunities. To apply, please send a letter of intent, CV and contact information for three references to ruslana@nullbu.edu.

Junior Group Leaders – Tenure Track

Junior Group Leaders – Tenure Track

Positions are available for outstanding scientists from any research field that addresses fundamental biological questions.

MFPL is also interested in recruiting scientists who work at the interface of medicine and biology. This includes the modelling of complex diseases in simple organisms, the bottom-up reconstitution of disease-relevant processes and quantitative and synthetic approaches to medicine using advanced technologies.

These tenure track positions are offered initially for six years with the possibility of tenure, based on a performance-focused evaluation according to international standards. These positions include internationally competitive salaries and start-up packages.

Vienna is the vibrant multicultural capital of AUSTRIA, repeatedly ranked among the top three cities worldwide for its quality of living. Child care facilities are available at the VBC. MFPL wishes to increase its share of female group leaders and applications from couples are also encouraged. The working language of the MFPL and VBC is English.

Application:

 https://www.mfpl.ac.at/de/ueber-uns/offene-stellen/position/news-detail/faculty-openings.html

DEAD-line: 5th of November

Fully-funded Postdoc Positions Available in New Lab Group at the NIH Main Campus, Bethesda, Maryland

Fully-funded postdoc positions are available in a new lab group starting at the NIH main campus in Bethesda, Maryland.  Research in the McJunkin lab has two major long-term goals:

1) to define the biological functions of miRNAs during embryogenesis and

2) to elucidate mechanisms of miRNA turnover. Using C. elegans as a model organism to address these questions, we will combine the strengths of classical forward genetics with CRISPR-Cas-9-mediated genome editing, next-generation sequencing, cell biology, and biochemical techniques. Because embryonically-expressed miRNAs exhibit a sharp decrease in abundance at the end of embryogenesis, our efforts to simultaneously study the biology of these miRNAs and the mechanisms of miRNA decay has the potential to uncover regulatory modules that couple miRNA decay to developmental timing.

The NIH Main Campus is a vibrant and collaborative research environment boasting over four hundred research groups and an active postdoc community. Bethesda, Maryland is part of the Washington, D.C. metropolitan area, and the NIH Main Campus is easily accessible by the Washington, D.C. subway system.

Applicants must have completed a Ph.D. within the last three years. Expertise in molecular biology and strong verbal and written communication skills are required. Experience in either RNA biology or C. elegans research is desirable. International scientists and U.S. citizens are equally eligible for these fully-funded positions.

For more information, please see our website (bit.ly/mcjunkin). To apply, please send a cover letter describing which aspect of our research program you are interested to pursue, a CV, and contact information for three references to mcjunkin@nullnih.gov.

Postdoctoral Position to Study RNA-Protein Complexes and Non-coding RNA in New York

A postdoctoral position is available immediately in the laboratory of Dr. Alexander Serganov at New York University School of Medicine. We are looking for enthusiastic, highly motivated and creative individuals with a strong interest in applying multidisciplinary approach and cutting-edge methodology to study RNA-mediated gene expression control. We are presently focusing our efforts on RNA-protein complexes and non-coding RNAs from bacteria and mammals, using structural (cryo-EM and X-ray), biochemical (including genome-wide) and biophysical methods. Research topics include transcriptional and translational control, mRNA modification, RNA degradation, and RNA-protein complexes in human diseases.

The candidate should hold a Ph.D. degree in structural biology, biochemistry, molecular biology, or related fields. Qualified candidates should have strong background in routine molecular biology techniques and protein purification. Experience in X-ray crystallography, cryo-EM and RNA research is highly desirable. Good communication in English is expected.

The Serganov laboratory (www.serganovlab.com) is located on the NYU Langone campus at 31st Street and First Avenue in midtown Manhattan, New York, USA. The postdoc will benefit from the vibrant scientific environment and the outstanding School infrastructure that supports the most advanced technologies including robotic X-ray facility, cryo-EM facility with Titan Krios and other cutting-edge microscopes, and over 20 other facilities. A postdoc will be involved in collaboration with leading groups and receive a competitive salary, excellent benefits, and subsidized housing.

Interested applicants should submit a detailed CV, brief statement of research interests with description of previous research experience and contact information (email addresses and telephone numbers) of three references to Dr. Alexander Serganov at alexander.serganov@nullNYUMC.org

Postdoctoral Position Available, Department of Molecular and Cell Biology, Boston University Medical Campus

Postdoctoral Scholar position is available in the laboratory of Dr. Ruslan Afasizhev at the Department of Molecular and Cell Biology, Boston University Medical Campus.

Our NIH-funded program focuses on the mechanisms of RNA processing in trypanosomes.   Current projects cover mitochondrial transcription, mRNA editing, mRNA stability, translation and small RNAs biogenesis. For more details, please see recent publications listed below.  Our collaborations extend into structural biology, mass spectrometry, drug design and bioinformatics.

Required qualifications include strong background in molecular biology and biochemistry, and a record of peer-reviewed publications.  Experience in RNAi, bioinformatics, RNA-Seq, ribosome profiling, protein purification, mass spectrometry and parasite genetics is desirable, but not required.

This position carries a starting salary of $45,000 for a junior candidate, or commensurate with experience, plus health benefits. Funding will be provided for up to three years although fellowship applications are encouraged.

Boston University Medical Campus is located in the vibrant South End area of Boston and offers a highly collaborative environment, unlimited networking possibilities in a thriving biomedical community, excellent core facilities and outstanding cultural and recreational opportunities. To apply, please send a letter of intent, CV and contact information for three references to ruslana@nullbu.edu.

 

Postdoctoral Position Available Immediately

A postdoctoral position is available immediately to study the regulation of transcriptome and translation in the gem cells and early embryos. Some of the current projects aim to investigate the effect of the RNA localization and translation between different stages of the cell cycle.

The position is open until filled.

Interested candidates must have received a Ph.D. degree in cell biology, biochemistry or related discipline, and be highly motivated to pursue and design innovative research directions.

Applications should include a CV, description of research interests and prior accomplishments, contact information of at least 3 references and preferred start date. Please e-mail application materials to susor@nulliapg.cas.cz

Postdoctoral position to study the regulation and functions of localized RNAs

A postdoctoral position to study the regulation and functional roles of localized RNAs is available in Dr. Stavroula Mili’s lab at the National Cancer Institute, National Institutes of Health, Bethesda, MD. The lab is interested in understanding the regulation of RNA localization by cancer-associated proteins and the contribution of localized RNAs to tumor progression. The work relies on a variety of cell biological, microscopical and biochemical approaches in 2D and 3D cell culture systems. Some of the current projects aim to investigate the effect of the mechanical properties of the extracellular matrix on RNA localization, and the coupling between RNA localization and translation using single-molecule imaging approaches. The research program is funded by the NIH Intramural program and is supported by state-of-the-art facilities on the NIH campus.

Interested candidates must have received a Ph.D. degree in cell biology, biochemistry or related discipline, and be highly motivated to pursue and design innovative research directions.

Applications should include a CV, description of research interests and prior  accomplishments, contact information of at least 3 references and preferred start date. Please e-mail application materials to voula.mili@nullnih.gov

The NIH is dedicated to building a diverse community in its training and employment programs.

DHHS/NIH is an Equal Opportunity Employer.

Tenure Track Assistant Professor Faculty Position

The Department of Chemistry at Case Western Reserve University (CWRU) invites applications for a tenure track Assistant Professor faculty position in the research area of RNA chemistry. Preference will be given to candidates with demonstrated expertise in applying chemical methods to study RNA structure-function, protein-RNA complexes, or RNA-targeted small molecule synthesis. The successful candidate will be expected to develop an internationally visible research program supported by external funding and will contribute to teaching within the areas of organic chemistry. Normal teaching load for faculty with active research programs is one course per semester plus ancillary duties. A Ph.D., research publications, and postdoctoral (or comparable industrial) experience are required.

This position is related to recent Departmental and University strategic initiatives, and builds upon the strong history of RNA science at CWRU. The new hire will thus complement current expertise in RNA science, and be expected to establish collaborations with scientists at centers such as the Center for RNA Science & Therapeutics, the Center for AIDS Research, and the Case Comprehensive Cancer Center.

To be considered, a letter of application, CV, and a summary of research plans should be sent by email c/o Suzi Mason (sxm763@nullcase.edu) before November 10, 2017. In addition, three letters of recommendation should be independently emailed directly to Suzi Mason by this date.

In employment, as in education, Case Western Reserve University is committed to Equal Opportunity and Diversity. Women, veterans, and members of underrepresented minority groups and individuals with disabilities are encouraged to apply.

Case Western Reserve provides reasonable accommodations to applicants with disabilities. Applicants requiring reasonable accommodation for any part of the application and hiring process should contact the Office of Inclusion, Diversity and Equal Opportunity at 216-368-8877 to request a reasonable accommodation. Determinations as to granting reasonable accommodations for any applicant will be made on a case-by-case basis.

Postdoctoral Position for Research on Human Argonaute Proteins

A postdoctoral position is available immediately in the Nakanishi lab in the Department of Chemistry and Biochemistry, The Ohio State University. We recently revealed that Argonaute3 cleaves RNAs, but the slicing activity heavily depends on the guide RNA unlike Argonaute2 (Mi Seul et al., Nucleic Acids Research, in press). The goal of the project is to understand how four human Argonaute paralogues behave differently. The project will explore the mechanisms of RNA silencing, alternative splicing, defense against viral infection, and long noncoding RNA-mediated biological processes. We also have a protein engineering project of developing Argonaute as a tool.

Candidates should have a Ph.D. and less than five years of postdoctoral experience. Successful applicants should have a significant experimental training in two or more of the following: in vitro RNA transcription, protein expression in human cell lines, high-throughput SHAPE, RNAseq, PAR-CLIP, recombinant protein expression and purification from E. coli and insect cells, ITC, enzyme kinetics, Cryo-EM, X-ray crystallography, SAXS, and programming in Python.

To apply for this position, email to Dr. Kotaro Nakanishi, nakanishi.9@nullosu.edu, including a one-page motivation letter, CV, and three references (email and phone).

For more information, visit http://u.osu.edu/nakanishilab/.

Postdoctoral Fellow Position at the University of California, Riverside

We seek a talented and motivated Postdoctoral Fellow to work on RNA biology and epigenetics in neurons and stem cells.

The position is in a newly established laboratory in the Department of Biochemistry at the University of California, Riverside. A successful applicant will have a strong background in molecular and cell biology, biochemistry and genetics. Prior experience with neurobiology, stem cell biology and/or computational biology is desirable. For more information about the lab, please visit https://www.murnlab.info/.

The position is available starting October 2017. To apply, please email a short cover letter describing your research interests and motivation for joining the lab, your CV, and contact information of three referees to Dr. Jernej Murn at jernej.murn@nullucr.edu.

Postdoctoral Position Available in the Laboratory of Dr. Erbay Yigit

An industrial postdoctoral position is immediately available in the laboratory of Dr. Erbay Yigit at New England Biolabs (NEB) in Ipswich, MA. Projects will be a part of a research program that aims to identify and characterize enzymes that post-transcriptionally modify RNA using genetic and biochemical approaches. Research will be undertaken in a highly collaborative environment where publication of results is expected. Duration is 3 years.

Primary Responsibilities:
• Characterize and engineer RNA modifying enzymes.
• Carry out and publish original scientific research.
• Be a creative, independent and productive scientist.
• Interact and collaborate with other members of the RNA Biology Division and other research divisions to further program and division goals.

Required Qualifications:
• Ph.D. in Biochemistry, Molecular Biology or related field.
• Technical expertise in RNA manipulation, RNA enzymes and analysis.
• Technical expertise in standard molecular biology techniques.
• Publication of original scientific work in high-quality journals.
• Demonstrated scientific communication in both formal and informal settings.
• Excellent verbal and written communications skills.
• Strong work ethic, emphasizing both efficiency and quality of work.

Preferred Qualifications:
• Expertise in RNA enzymes.
• Expertise in protein purification.
• Expertise in protein engineering.
• Experience with analysis of large datasets and high-throughput sequencing.

Email: yigit@nullneb.com

Postdoctoral Position Available in the Penalva Lab

A Postdoctoral position is available in the Penalva lab (ccri.uthscsa.edu/LPenalva.html) at the Children’s Cancer Research Institute – UTHSCSA, San Antonio, Texas. CCRI provides an outstanding research environment with state of the art facilities and equipment. Our NIH funded projects involve genomic and molecular analyses of splicing and translation in the context of brain tumors. Successful candidates are expected to have:
• Ph.D in Molecular Biology or related field.
• Strong publication record.
• Interest and expertise in RNA biology and genomics including deep sequencing approaches such as Riboseq, CLIP, RIP.
• Basic understanding of bioinformatics and cancer biology
• Motivation, independence and team mentality.
Candidates should provide the following:
• Cover letter with summary of research experience, interests and career goals
• CV with publication list and contact information for at least two references.
Please submit all application materials electronically to:
penalva@nulluthscsa.edu

Postdoctoral Position Available in the Laboratory of Dr. Toni R. Pak

A postdoctoral position is available in the laboratory of Dr. Toni R. Pak in the Department of Cell and Molecular Physiology, Loyola University Chicago. The project will focus on ligand-independent signaling of nuclear receptors in the aged brain, with an emphasis on alternative RNA splicing and proteomics. Molecular biology techniques including viral vector construction, ChIP and RIP assays, nuclear run-on assays, qPCR, and ability to work with both whole animal and in vitro models is required. In addition, experience with HPLC and MS/MS using targeted approaches to detect posttranslational modifications is preferred.

The successful candidate will be highly motivated, have strong oral and written communication skills, and have a Ph.D. in the field of RNA biology, molecular biology, endocrinology, and/or neuroscience. Interested applicants should send a cover letter describing their experience and interests, CV, and names of 3 references. The packet should be sent as a single pdf file to tpak@nullluc.edu.

Postdoctoral Position Available in the Fu Laboratory at the University of Rochester

A Postdoctoral position is available in the Fu laboratory at the University of Rochester, Department of Biology. Our group investigates the cellular roles of nucleic acid modification enzymes in biological processes ranging from neurodevelopment to the cellular stress response. Current projects are aimed at understanding the role of RNA modifications in human disorders using mammalian tissue culture and mouse models.

Successful candidates are expected to have:

• Ph.D in Molecular Biology, Computational Biology or related field.
• Expertise in RNA biochemistry coupled with deep sequencing approaches such as ribosome profiling, CLIP-seq etc.
• Strong background in transcriptomics, bioinformatics and programming
• Self-motivation and the ability to work independently as well as collaboratively

Candidates should provide the following:

• Cover letter with a short statement of research experience, interests and goals
• CV with publication list and contact information for at least two references.

Please submit all application materials electronically to:
dragonyfu@nullrochester.edu

Additional information and lab publications are available on our website:
http://blogs.rochester.edu/dfulab/

The position is available immediately with a flexible start date.

Postdoc Positions Available in the Rafal Ciosk Lab

Postdoc positions are available in the Rafal Ciosk lab (starting in January 2018) at the Institute of Bioorganic Chemistry, Polish Academy of Sciences. Successful candidates will engage in the research project “Regulation of body fat: From novel mechanisms to therapeutic targets” funded by Foundation for Polish Science (FNP).

We study molecular mechanisms, particularly posttranscriptional, controlling gene expression. We also investigate how these mechanisms impact physiology and, in disease, can lead to pathologies. We primarily, but not exclusively, use C. elegans as a model system.
For more details, please visit:
http://www.ibch.poznan.pl
http://www.fmi.ch/research/groupleader/?group=114

Salary: 12,000-15,000 PLN gross, depending on the candidate’s research experience and achievements.

Contract period: 36 months

For application, please submit the following documents to:
applications@nullibch.poznan.pl

1. Letter of application addressed to the Director of IBCH PAS
2. Motivation Letter and Curriculum Vitae
3. Certified copy of the PhD diploma (or MSc diploma along with a certification issued by the supervisor, confirming the estimated date of doctoral dissertation defense);
4. Detailed information on the candidate’s research, organizational experience and achievements including:
– the list of scientific papers
– list of inventions, patents, implementations
– information on managing or participating in research projects
– information on scientific scholarships
– information on awards, prizes, distinctions, etc.
5. Contact details of three referees, including a PhD advisor

Please include in your letter:
“I hereby give consent for my personal data included in my application to be processed for the purposes of the recruitment process under the Personal Data Protection Act as of 29 August 1997, consolidated text: Journal of Laws 2016, item 922 as amended.”

Postdoctoral Fellow Position – University of Colorado School of Medicine

The spatial organization of proteins within cells is critical to their proper function.  This is especially true in polarized cells and those with elongated structures like neurons.  This spatial arrangement can be achieved by transporting fully translated proteins to their required destination. Alternatively, it can be done by transporting the instructions for making the protein, that is, an mRNA, to the desired location followed by on site protein production.  The latter method has several advantages, including the allowance of rapid and robust translational responses to received stimuli.  This RNA localization strategy is used widely in neurons.  Approximately one thousand RNA transcripts are localized to the projections of neuronal cells (neurites).  Their localization is controlled through the interaction cis RNA sequences in the transcripts (so called zipcodes for their ability to induce spatial sorting) and protein factors that bind these sequences and facilitate their movement. Of the approximately one thousand localized transcripts in neurons, the zipcodes that control their localization are known for only 10-20, representing a large gap in our understanding of this process.  Mutations in the RNA-binding proteins that mediate RNA transport are associated with neurological disease, emphasizing the importance of RNA localization in the physiology of neuronal cells.

Active areas of research include (1) the mechanisms by which RNA-binding proteins involved in localization recognize and bind their mRNA targets, (2) high-throughput screening to identify RNA sequences with the ability to drive localization to neurites, and (3) the dynamic changes in localized transcriptomes in response to stimuli.

For additional information about the laboratory or to see recent publications, visit www.taliaferrolab.com.

Two Highly Motivated Postdoctoral Research Fellows to Carry Out NIH-Funded Research

The Motamedi Lab at the Harvard Medical School (HMS) and Massachusetts General Hospital (MGH) Cancer Center has vacancies for up to two highly motivated Postdoctoral Research Fellows to carryout NIH-funded research. The Fellow will have simultaneous academic appointments at HMS and MGH and contribute to ongoing research exploring the molecular mechanisms by which small and long non-coding RNAs contribute to the establishment of epigenetic states in response to stress and cellular dormancy using yeast and mammalian cells as models. These projects will explore mechanisms of RNAi-mediated silencing, RNA turnover, antisense transcription, and chromatin biology. The ideal candidates have (or will have) productive Ph.D. publication records, compatible with procuring external funding, with training in tissue culture, molecular biology, biochemistry, and/or cell biology. Because the Fellows will generate large scale genomic or proteomic datasets from yeast and/or human cells, previous experience with handling large datasets is a plus, but not required.

The laboratory is grounded in basic research and is working closely with the clinical researchers at MGH Cancer Center and HMS communities. The Cancer Center is composed of a vibrant milieu of world-class basic and clinical researchers, creating an exceptional environment for accelerating basic biology discoveries into clinical research.

See the cover story of the 2016, Dec 15th issue of Molecular Cell entitled “Survival in Quiescence Requires the Euchromatic Deployment of Clr4/SUV39H by Argonaute-Associated Small RNAs” for latest research (doi: 10.1016/j.molcel.2016.11.020).

Please email a one-page cover letter, CV, and contact information of three referees to:
Mo Motamedi, Ph.D.
Massachusetts General Hospital Cancer Center
Harvard Medical School
Room 7.212, 149 13th street,
Charlestown, MA
02129
mmotamedi@nullhms.harvard.edu
www.massgeneral.org/motamedilab