Employment Opportunities

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Postdoc Positions Available in the Rafal Ciosk Lab

Postdoc positions are available in the Rafal Ciosk lab (starting in January 2018) at the Institute of Bioorganic Chemistry, Polish Academy of Sciences. Successful candidates will engage in the research project “Regulation of body fat: From novel mechanisms to therapeutic targets” funded by Foundation for Polish Science (FNP).

We study molecular mechanisms, particularly posttranscriptional, controlling gene expression. We also investigate how these mechanisms impact physiology and, in disease, can lead to pathologies. We primarily, but not exclusively, use C. elegans as a model system.
For more details, please visit:
http://www.ibch.poznan.pl
http://www.fmi.ch/research/groupleader/?group=114

Salary: 12,000-15,000 PLN gross, depending on the candidate’s research experience and achievements.

Contract period: 36 months

For application, please submit the following documents to:
applications@nullibch.poznan.pl

1. Letter of application addressed to the Director of IBCH PAS
2. Motivation Letter and Curriculum Vitae
3. Certified copy of the PhD diploma (or MSc diploma along with a certification issued by the supervisor, confirming the estimated date of doctoral dissertation defense);
4. Detailed information on the candidate’s research, organizational experience and achievements including:
– the list of scientific papers
– list of inventions, patents, implementations
– information on managing or participating in research projects
– information on scientific scholarships
– information on awards, prizes, distinctions, etc.
5. Contact details of three referees, including a PhD advisor

Please include in your letter:
“I hereby give consent for my personal data included in my application to be processed for the purposes of the recruitment process under the Personal Data Protection Act as of 29 August 1997, consolidated text: Journal of Laws 2016, item 922 as amended.”

Postdoctoral Fellow Position – University of Colorado School of Medicine

The spatial organization of proteins within cells is critical to their proper function.  This is especially true in polarized cells and those with elongated structures like neurons.  This spatial arrangement can be achieved by transporting fully translated proteins to their required destination. Alternatively, it can be done by transporting the instructions for making the protein, that is, an mRNA, to the desired location followed by on site protein production.  The latter method has several advantages, including the allowance of rapid and robust translational responses to received stimuli.  This RNA localization strategy is used widely in neurons.  Approximately one thousand RNA transcripts are localized to the projections of neuronal cells (neurites).  Their localization is controlled through the interaction cis RNA sequences in the transcripts (so called zipcodes for their ability to induce spatial sorting) and protein factors that bind these sequences and facilitate their movement. Of the approximately one thousand localized transcripts in neurons, the zipcodes that control their localization are known for only 10-20, representing a large gap in our understanding of this process.  Mutations in the RNA-binding proteins that mediate RNA transport are associated with neurological disease, emphasizing the importance of RNA localization in the physiology of neuronal cells.

Active areas of research include (1) the mechanisms by which RNA-binding proteins involved in localization recognize and bind their mRNA targets, (2) high-throughput screening to identify RNA sequences with the ability to drive localization to neurites, and (3) the dynamic changes in localized transcriptomes in response to stimuli.

For additional information about the laboratory or to see recent publications, visit www.taliaferrolab.com.

Two Highly Motivated Postdoctoral Research Fellows to Carry Out NIH-Funded Research

The Motamedi Lab at the Harvard Medical School (HMS) and Massachusetts General Hospital (MGH) Cancer Center has vacancies for up to two highly motivated Postdoctoral Research Fellows to carryout NIH-funded research. The Fellow will have simultaneous academic appointments at HMS and MGH and contribute to ongoing research exploring the molecular mechanisms by which small and long non-coding RNAs contribute to the establishment of epigenetic states in response to stress and cellular dormancy using yeast and mammalian cells as models. These projects will explore mechanisms of RNAi-mediated silencing, RNA turnover, antisense transcription, and chromatin biology. The ideal candidates have (or will have) productive Ph.D. publication records, compatible with procuring external funding, with training in tissue culture, molecular biology, biochemistry, and/or cell biology. Because the Fellows will generate large scale genomic or proteomic datasets from yeast and/or human cells, previous experience with handling large datasets is a plus, but not required.

The laboratory is grounded in basic research and is working closely with the clinical researchers at MGH Cancer Center and HMS communities. The Cancer Center is composed of a vibrant milieu of world-class basic and clinical researchers, creating an exceptional environment for accelerating basic biology discoveries into clinical research.

See the cover story of the 2016, Dec 15th issue of Molecular Cell entitled “Survival in Quiescence Requires the Euchromatic Deployment of Clr4/SUV39H by Argonaute-Associated Small RNAs” for latest research (doi: 10.1016/j.molcel.2016.11.020).

Please email a one-page cover letter, CV, and contact information of three referees to:
Mo Motamedi, Ph.D.
Massachusetts General Hospital Cancer Center
Harvard Medical School
Room 7.212, 149 13th street,
Charlestown, MA
02129
mmotamedi@nullhms.harvard.edu
www.massgeneral.org/motamedilab

Postdoctoral Researcher Position Available Immediately

Postdoctoral Researcher position available immediately in the Laboratory of Dr. Mingyi Xie (Assistant Professor, Department of Biochemistry and Molecular Biology, Cancer Center, School of Medicine, University of Florida) to study the Function and biogenesis of alternatively-processed microRNAs and Integrator complex-mediated RNA processing and gene regulation. The duration of this position will be 5 years, while the contract will be renewed on a yearly basis.

Applicants should submit the following to mingyi.xie@nullufl.edu:
1)      Cover letter stating: laboratory experience in RNA/protein biochemistry and bioinformatics; your long-term career goals; date of availability to begin postdoc research
2)      Curriculum vitae (including publications and awards/honors)
3)      List of at least three references

Dr. Mingyi Xie was trained in the laboratory of Dr. Joan Steitz at Yale University (2010-2016), where he documented two surprising microRNA (miRNA) biogenesis pathways:

  • Herpesvirus saimiri (HVS)-miRNAs are processed by the host Integrator complex, a 14-subunit complex best known for executing the 3′-end cleavage of cellular small nuclear RNAs (snRNAs) (Cazalla, Xie and Steitz-Molecular Cell-2011; Xie et al.,-Genes & Development-2015).
  • Mammalian m7G-capped precursor miRNAs are generated from RNA polymerase (Pol) II transcription initiation sites. Whereas the nuclear-cytoplasmic export of capped pre-miRNAs is mediated by Exportin-1 (Xie et al.,-Cell-2013; Xie and Steitz-RNA Biology-2014).

The Xie lab’s immediate research goal is to further delineate the unique modes of miRNA production, including Integrator-mediated RNA metabolism, and understand the functions of these special miRNAs in herpesviruses and their hosts. Such research will allow the design of therapies for related oncogenic herpesviruses and cancers.

University of Florida (UF) is a vibrant intellectual community with many cross-disciplinery interactions. UF is ranked as top-50 world university and top-15 public university in the United States by USNEWS. Gainesville is a delightful and family-friendly city that is 1.5 hours away from major cities like Orlando, Jacksonville and Tampa Bay.

Visit http://xie.biochem.med.ufl.edu for more information

POSTDOCTORAL POSITION AVAILABLE IMMEDIATELY IN NEW YORK

NIH-funded postdoctoral position is available immediately in the Meier lab at the Albert Einstein College of Medicine to study the cellular impact of the bone marrow failure syndrome dyskeratosis congenita (DC). The ideal candidate will have a strong background in molecular cell biology and biochemistry with specific training in recombinant protein expression and purification, cell culture, and RNAseq.

DC is primarily caused by mutations in one of the factors of H/ACA RNA–protein complexes, small ribonucleoproteins (RNPs). Although several hundred of these RNPs in every cell are involved in ribosome biogenesis, telomere maintenance, pre-mRNA splicing, and more, DC seems to primarily affect telomeres. We are investigating if this is truly so and why or if other functions/RNPs are affected as well.

Albert Einstein College of Medicine is a vibrant scientific community that caters to postdoctoral researchers through its Belfer Institute for Advanced Biomedical Studies. Postdoctoral housing is available. For more details check out the webpage of the Belfer Institute:
http://www.einstein.yu.edu/research/belfer-institute/

Interested candidates should send their CV, the addresses of three references (including email and phone number), and a one-page statement of past achievements and current and future research interests to tom.meier@nulleinstein.yu.edu

PhD position: Exploration of novel RNA-based mechanisms for rapid gene regulation during neuronal plasticity

A 4 year-PhD position is available at the Biozentrum, University of Basel, Switzerland to explore novel, RNA-based mechanisms of neuronal plasticity.

We recently revealed a novel, transcription-independent mechanism that releases neuronal transcripts within minutes of neuronal stimulation (Mauger et al., Neuron, 2016). We observed that a substantial population of transcripts retaining select introns are stably maintained in the nucleus at rest, while neuronal activity elicits splicing completion, thereby, producing functional mRNAs. The goal of the PhD project is to explore the molecular mechanism of this novel gene regulation pathway and its contribution to synaptic plasticity. The successful candidate will use a combination of transcriptome-wide analysis, modern cellular & molecular methods, high resolution imaging, and advanced neuroscience methods. Both in vitro and mouse in vivo approaches will be used.

We are looking for a highly motivated student eager to understand the novel RNA regulatory processes in neuron biology and function. Candidates with previous expertise in either RNA biology or neurobiology will be highly appreciated. Basic knowledge in programming or deep motivation to learn computational methods is required.

The PhD student will be supervised by Dr. Oriane Mauger (SNSF Ambizione fellow, semi-independent position). The position is embedded in the group of Prof. Peter Scheiffele who will serve as a co-supervisor. The student will benefit from the scientific environment, the technical expertise and infrastructure of the Scheiffele laboratory as well as the outstanding University infrastructure supporting the most advanced technologies including sciCore (supports in computational analysis), Quantitative Genomics Facility, Proteomics Core Facility, Centre for Transgenic Models and Imaging Facilities.

Please send applications including a motivation letter, CV, names and emails of two references (as a single pdf) to oriane.mauger@nullunibas.ch.

Post-Doctoral Position, Laboratory of Sandra Wolin, National Cancer Institute

The Wolin laboratory has recently moved to the National Cancer Institute (NCI) at the National Institutes of Health (NIH) as part of a major new initiative in RNA Biology.

A fully funded postdoctoral position is available in the areas of noncoding RNA function, RNA surveillance pathways, and the mechanisms by which defects in RNA decay pathways contribute to diseases such as cancer and autoimmunity. We seek highly motivated, enthusiastic, thoughtful and creative candidates with strong publication records.

Our group is part of the newly formed RNA Biology Laboratory in the Center for Cancer Research. We are part of the Center for Cancer Research’s RNA Initiative, which includes more than 50 laboratories evenly split between the Frederick and Bethesda campuses of the National Cancer Institute. The environment is highly collaborative and collegial, with the ability to interact with a wide range of scientists and clinicians. The stable funding and numerous core facilities and resources available at the NCI and the NIH make this an ideal position for a motivated candidate who is seeking additional training in RNA biology.

A more complete description of our research and laboratory can be found at https://ccr.cancer.gov/RNA-Biology-Laboratory/sandra-l-wolin

Candidates should have a Ph.D. and/or an M.D. and less than five years of postdoctoral experience. Candidates should also have significant experimental training in molecular biology, genetics or biochemistry, as evidenced by publications.

To apply, please send a cover letter discussing your interests in the position, your CV, and contact information for three references to sandra.wolin@nullnih.gov

This position is subject to a background investigation. The NIH is dedicated to building a diverse community in its training and employment programs. The Department of Health and Human Services, NIH, and NCI are Equal Opportunity Employers.

NIH-funded Postdoctoral Fellowship Position in RNA Metabolism

NIH-funded Postdoctoral Fellowship Position, to begin Oct 1, 2017 or later (duration: 2-5 yrs).
NIH-funded Postdoctoral Fellowship Position in RNA Metabolism
National Institutes of Health (NIH), Bethesda, Maryland

The Fellow will investigate molecular mechanisms involved in mRNA metabolism relevant to cellular tRNA levels and certain modifications as determined by tRNA-Seq. Focus will be on effects of varying tRNA levels under natural conditions on mRNA stability and translation dependent on codon use during the execution of certain genetic programs such as differentiation.  Candidates must hold a Ph.D. or M.D. and have less than 5 years postdoctoral experience.  Expertise in molecular biology, genetics and biochemistry is required, as are strong letters of recommendation.  The successful candidate will confer with the principal investigator but must work independently toward self-directed research and have good technical, presentation, and communication skills.

Interested candidates should email a cover letter that describes in detail their specific interests in the research objectives of the Maraia lab.

  • Send a cover letter, C.V., and the names of three references with their email addresses and telephone numbers by Email to:
    Richard J. Maraia, M.D.
    Email: maraiar@nullmail.nih.gov

Maraia lab interests

  • mRNA biased codon use and effects of cellular tRNA match on stability and translation.
  • tRNA modifications i6A37 and m2,2G26, their roles in translation, health and disease.
  • Mechanisms of La-related protein -4 (LARP4) function in mRNA poly(A) stability and translation.
  • Role of the La protein in tRNA production.

•Mechanisms of transcription termination by RNA polymerase III.

University of Oregon Tenure-Track Biochemistry Faculty Member at the Assistant Professor level

The Department of Chemistry and Biochemistry at the University of Oregon (chemistry.uoregon.edu) invites applications for a tenure-track Biochemistry faculty member at the Assistant Professor level to begin in Fall 2018 or later. Biochemistry research at the University of Oregon takes place in the context of the Institute of Molecular Biology (molbio.uoregon.edu), which promotes interdisciplinary interactions between life science researchers in the departments of Chemistry and Biochemistry, Biology and Physics. A Ph.D. is required.

We seek applicants from all areas of biochemistry and structural biology who are using advanced approaches to study mechanisms of cellular function. New faculty will join a rich and collaborative atmosphere with existing strengths in host-pathogen interactions, stem cell biology, epigenetics, RNA metabolism, cell polarity, and cytoskeletal function. Successful candidates will have the potential for establishing an outstanding independent research program and excellence in teaching at the undergraduate and graduate levels. They will also support and enhance a diverse learning and working environment.

To assure full consideration, application materials should be received by October 9, 2017. Please upload a cover letter, curriculum vitae, a statement of research plans and objectives, and a brief statement of teaching philosophy or interests here: https://academicjobsonline.org/ajo/jobs/9448. The candidate should also arrange for three letters of recommendation to be uploaded directly by the recommenders. Review of application materials will continue until the position is filled.

UO is dedicated to the goal of building a culturally diverse and pluralistic faculty committed to teaching and working in a multicultural environment and strongly encourages applications from minorities, women, and people with disabilities. Applicants are encouraged to include in their cover letter information about how they will further this goal.

Kieft Lab Seeking Post-Doctoral Researchers

The Kieft Lab is seeking motivated, enthusiastic, creative post-doctoral researchers to join us at the University of Colorado School of Medicine. This is an excellent opportunity to join a dynamic, cohesive, enthusiastic and thriving research group, and to establish an independent project on a novel RNA-focused scientific problem. New post-doctoral researchers in the Kieft Lab have the chance to design and pursue a project that melds their own interests and ideas with the established expertise of the lab. Positions are fully funded and available immediately.

Currently, the Kieft Lab is dedicated to understanding diverse roles played by RNA in healthy and diseased cells, with a particular interest in how RNA structure and structural dynamics drive function. We have focused mainly on RNAs of viral origin; we hope to understand how these RNAs are critical for viral diseases and also to learn fundamental rules of how RNA works in biology. Our approaches include cell culture-based methods with disease relevant cells, in vitro activity assays, biochemical studies, x-ray crystallography, cryo-EM, biophysical methods, and virology. However, we are is always open to new questions and different approaches, driven by curiosity!

The lab is located on the new Anschutz Medical Campus within the highly collegial Department of Biochemistry and Molecular Genetics and is part of the RNA BioScience Initiative. Denver is a great place to live and to do research. Motivated, curious and independent individuals interested in joining the Kieft Lab should send (by e-mail) a letter of inquiry stating research interests along with a CV and contact information of three references: Jeffrey.kieft@nullucdenver.edu

Open Post-doc positions for research on circular RNAs (circRNAs) in the Kadener lab at Brandeis University

The Kadener lab recently relocated to the Boston area and we are looking for highly motivated post-doctoral fellows for exciting research on circular RNAs (circRNAs).

We are looking for 2 post-doctoral fellows for performing research on circRNA function. Our lab uses both Drosophila and mammalian systems to unravel the role of circRNAs in brain function and behavior. Our laboratory is one of the leaders in this new and exciting field of research. The studies will require the use of the most advanced biochemical, computational, genomic and neurobiology tools to determine the mechanisms by which circRNA regulate behavior and other neuron-related process. Our studies range from mechanistic biochemical and molecular characterization to the role of these molecules in neurobiology and behavior. Our work utilizes genomic, computational and system-level approaches.  These positions are set to start on October 1st but later start dates are possible.

Relevant publications from our lab in the field include: Pamudurti et al. Mol. Cell 2017;  Rybak-Wolf et al. Mol Cell 2015; Ashwall-Fluss et al. Mol. Cell 2014

In addition, we are looking for at least one post-doctoral researcher to study molecular and neural aspects of the circadian clock. This project involves the development and use of advance molecular, genomic, system-biology and neurobiology techniques to unravel mechanisms behind the robustness and plasticity of the circadian clock. The start date of the position is flexible.

Relevant publications of our lab in the field include: Buchumenski et al., PLoS Genetics 2017; Afik et al., NAR 2017; Mezan et al., Cell Reports 2016; Lerner et al., Nat Communications 2015; Bartok et al., EMBO J 2015; Weiss et al., PLoS Genetics, 2014

Previous experience in Drosophila genetics or neurobiology is advisable but not required. Computational applicants are encouraged to apply.

For more information about the lab, visit http: http://www.bio.brandeis.edu/faculty/kadener.html and http://kadenerlab.huji.ac.il

Note for German Applicants: Prof. Kadener is an Alexander von Humboldt Foundation award winner, so the Kadener lab can act as a host lab for Germans applying to the Feodor Lynen Research fellowship.

If you are interested, please email skadener@nullbrandeis.edu with a cover letter and CV.

Apply for a Postdoctoral Position on Pre-mRNA Splicing in the Staley Lab

Our goal is to understand the mechanisms that underlie nuclear pre-mRNA splicing, an essential step in eukaryotic gene expression. Pre-mRNA splicing is catalyzed by a massive ribonucleoprotein machine called the spliceosome. Using a variety of model organisms, especially baker’s yeast, we leverage a broad array of tools including genetics, genomics, cell biology, mathematical modeling, biochemistry, single molecule approaches, and structural approaches to gain a deep understanding of how the spliceosome catalyzes and regulates pre-mRNA splicing. Our lab comprises a group of creative, thoughtful, and motivated individuals at all career stages, including high school students, undergraduates, graduate students, postdocs and research professionals.

Find out more about our research and lab at our website: http://staley.uchicago.edu.

The Staley Lab now seeks a postdoctoral researcher to pursue one of a number of available projects; a suitable project will be selected based on the postdoc’s interests and experience. We seek applicants who are independent, motivated, rigorous, creative, and innovative. Applicants should have a solid publication record. Additionally, applicants should have strong written and oral communication skills and work well with others. Applicants should have or will shortly earn a PhD in molecular biology, cell biology, and/or genetics, although individuals from other disciplines seeking to change or bridge fields are encouraged to apply. Experience with RNA and approaches that include genetics, genomics, cell biology, biochemistry, biophysics, and/or mathematical modeling is preferred.

The interdisciplinary approach of our lab to research provides an exceptional environment for postdoctoral training. Our interdisciplinary approaches are facilitated by the lab’s proximity to other top disciplines within just a five minute walk, including the physical, medical, and evolutionary sciences; our lab is centered in the Biological Sciences Division at the University of Chicago (for more information, visit: http://biologicalsciences.uchicago.edu). Further, the broader community at the University of Chicago provides a unique and invigorating environment, where inquiry, debate, and all points of view are valued (for more information, visit: http://www.uchicago.edu). Note that the city of Chicago offers an enriching environment to live, with opportunities ranging from theater, art, comedy, and dining to professional sports and outdoor activities (for more information, visit: https://biosciences.uchicago.edu/life).

Interested and qualified candidates should submit the following to jstaley@nulluchicago.edu:

  1. i) a CV
  2. ii) contact information for three references

iii) a cover letter that includes a brief summary of your research accomplishments, your research interests – including your motivation for working in our lab, and your long term goals

The postdoctoral position is available immediately.

PhD Positions Available

PhD positions are available in Prof. Chun Kit Kwok’s lab in the Department of Chemistry at the City University of Hong Kong. We are looking for bright and motivated PhD students to investigate the role of RNA structure in co- and post-transcriptional regulation in the mammalian system. Researchers within the group will be exposed to diverse chemical and biochemical techniques at our laboratory. For more information, please visit kitkwok.weebly.com or contact Dr. Kwok by email.

Applicants with background in RNA biochemistry and molecular biology, as well as next generation sequencing are preferred.

If you are interested to join the group, please kindly send your i) cover letter, ii) academic transcripts and GPA, and iii) CV which includes a summary of past research experience and publication records, your research interests, and contact information of 2 referees to:

Chun Kit KWOK, Ph.D.
Assistant Professor
Department of Chemistry
City University of Hong Kong
Office: AC1-B6608
Lab: AC1-P2405
Phone: (852) 3442 6858
Fax: (852) 3442 0522
Email: ckkwok42@nullcityu.edu.hk

Two Ph.D. positions in circRNA biology available

We are looking for excellent and highly motivated young researchers to investigate the formation and functional role of circular RNAs in the mammalian system. These two positions are integrated in an EC-funded International Training Network (ITN) called cirRTrain (https://circrtrain.eu/), which focusses on circRNA biology. Research in circRTrain includes
● biochemistry and computational biology, genetics
● sequencing, imaging, RNA knockdown, CRISPR/Cas9
● model systems like worm, fly, mouse, human
● medical applications, biomarkers, new therapeutic strategies

Specifically, the two positions in the Bindereif group at the University of Giessen, Germany, are available immediately, for three years, and are for Ph.D. students working on the two projects (#5 / #6) described below.
http://www.uni-giessen.de/fbz/fb08/Inst/biochem/bindereif/Positions

Please send applications including motivation letter, your CV, transcripts of previous studies, and two names of references (as one single pdf) to:

Prof. Dr. Albrecht Bindereif
Institute of Biochemistry
Department of Biology and Chemistry
Justus Liebig University of Giessen
Heinrich-Buff-Ring 17
D-35392 Giessen
Germany
Tel: 49-641-99 35 420
FAX: 49-641-99 35 419
e-mail: albrecht.bindereif@nullchemie.bio.uni-giessen.de

Postdoctoral Positions Available

Postdoctoral positions are available in Dr. Junjie Guo’s lab in the Department of Neuroscience at Yale School of Medicine. The Guo lab studies questions at the intersection between RNA biology and neuroscience. Currently, we are interested in the roles of mRNA and noncoding RNA structures in neural development and neurodegenerative diseases, taking a combination of computational, biochemical, genetic, and genomic approaches. For more information, please visit our website (www.guo-lab.com) or contact Junjie by email.

Start date is flexible and can be as early as September 1, 2017. Researchers with strong interest in RNA biology and neuroscience, regardless of their training background, are welcomed to apply.  Expertise in any of the following areas is highly valued though not required:

  • RNA biochemistry
  • Mouse/fly genetic models
  • In vitro and in vivo models of neurodevelopment
  • High-throughput sequencing
  • Advanced imaging techniques

Please email your application to jguo1766@nullgmail.com, including:

  • A cover letter describing your past training, research interests and career goals
  • A detailed CV
  • Contact information of referees

Postdoctoral Position Immediately Available

A postdoctoral position is immediately available in the lab of Fátima Gebauer to investigate the role of novel RNA binding proteins (RBPs) in cancer progression. Fátima Gebauer leads a team of motivated researchers working on RNA regulation and translational control in Drosophila and human cancerous cells. For more information about the group, please visit http://www.crg.es/fatima_gebauer. The position is available to determine the molecular mechanisms underlying the effects of selected RBPs in melanoma progression, with a special focus on those involved in translational control and metabolism.

Qualified individuals should be highly motivated, self-driven, independent, proficient in English and with a solid publication record. Experience in RNA regulation, metabolism, and standard molecular biology and tissue culture techniques is essential. Experience in animal handling and/or proficiency with the manipulation of high-throughput data is desirable.
We offer work in a highly stimulating environment with state-of-the-art infrastructures, providing the successful applicant with unique professional career opportunities. The contract will have a maximum duration of 5 years, and a competitive salary based on professional experience.

Interested applicants, please contact Fátima Gebauer at fatima.gebauer@nullcrg.eu, and include a CV, motivation letter and the contact details of 2 referees.

Postdoctoral Position Immediately Available

A postdoctoral position is immediately available in the Landthaler laboratory at the Max-Delbrück Center for Molecular Medicine in Berlin, Germany.

The main research interest of the lab is the regulation of gene expression by RNA-binding proteins. The objectives are to explore the connection between distinct cellular metabolic programs and regulation of gene expression at the posttranscriptional level. The aim is to identify metabolic pathways that modulate protein-RNA complexes, RNA structure and RNA modifications using high-throughput approaches.

Required qualifications are a PhD degree or equivalent with a documented background in RNA biology. Applications should be written in English, comprise of a cover letter with a brief statement of research interests, CV with a publication list and contact information of at least two referees. Documents should be in PDF format and submitted via e-mail (markus.landthaler@nullmdc-berlin.de and sabrina.deter@nullmdc-berlin.de).
This position is a full-time, 24 month appointment with an opportunity for renewal based on performance and funding. Informal inquiries regarding this position are welcome.

Seeking Highly Motivated Postdoctoral Associates

The Meyer lab in the Department of Biochemistry at Duke University is currently seeking highly motivated postdoctoral associates who are interested in RNA biology. Studies in the lab are focused on understanding the role of RNA methylation in nervous system function, as well as elucidating the complex regulatory pathways that control RNA modifications. Individuals with experience in RNA biology, biochemistry, genetics, or neurobiology are especially encouraged to apply.

Requirements:
– PhD in a relevant field (such as biology, biochemistry, neurobiology, or genetics).
– Excellent communication skills and an ability to work well with others.
– Demonstration of past research productivity (publications and/or patents).

How to apply:

Send a cover letter, your CV, and the names/contact information of three references to Dr. Kate Meyer (kate.meyer@nullduke.edu).

For more information on our lab, visit www.themeyerlab.com.

Postdoctoral Research Associates

The Zamudio lab in the Department of Molecular Cellular and Developmental Biology and the Broad Stem Cell Research Center at UCLA is seeking career-driven and creative Postdoctoral Research Associates to join our multidisciplinary team. We are studying new mechanisms of gene regulation by functional noncoding RNAs using a combination of genomic, system biology, biochemistry and cell biology approaches. Laboratory research will involve a variety of cutting-edge approaches in RNA and stem cell biology providing an ‪excellent research training opportunity in genomics, bioinformatics and translational science. ‬

Ph.D. in Molecular Biology, Cell Biology, Genetics/Genomics, Bioinformatics, Chemistry or a related field is required. ‪Experience and publication record in statistical genomics, computational biology, stem cell biology or related fields‬ including analysis of CLIP, ChIP, WGBS and RNA-seq data is preferred, but not required. ‪Applicants with strong background in RNA molecular biology, genetics or related fields who are interested in developing new genomic approaches in mouse cancer models are also encouraged to apply. ‬Competitive candidates will have a record of scientific productivity, leadership and collaborations.‬‬

Start Date: ASAP

Applicants should submit the following to jesse.zamudio@nullucla.edu:
1) Cover letter stating: laboratory experience in RNA biology and bioinformatics; your long-term career goals; date of availability to begin postdoc research
2) Curriculum vitae (including publications and awards/honors)
3) List of at least three references

Jesse Zamudio was trained in the laboratory of Dr. Phil Sharp at the MIT Cancer Center. At MIT, he characterized regulation by the RNAi pathway in mammalian cells. Using system biology approaches, he found new species of RNA bound to Argonaute in a Dicer-dependent and Dicer-independent manner. The Zamudio lab’s research goal is to characterize new mechanisms of RNA-mediated regulation essential for development and involved in disease progression.