Two postdoctoral research associate positions are available to study molecular mechanisms of viral and cellular translation and of translation-associated quality control processes in eukaryotes in the laboratories of Tatyana Pestova and Christopher Hellen at the State University of New York Downstate Medical Center in Brooklyn, NY, USA. Our NIH-funded research uses a range of biochemical and molecular biology approaches, and currently focuses on characterization of (1) canonical and non-canonical modes of translation initiation in mammals, including IRES-mediated initiation, (2) mechanisms of translation termination and ribosome recycling, and (3) events downstream of termination, with a focus on quality control processes.
Required qualifications include a Ph.D. in the field of Molecular Biology, Biochemistry or a related field, and practical experience in modern RNA and/or protein biochemistry, including the expression and purification of native/recombinant proteins and the functional analysis of proteins and RNA-protein complexes. Our research involves active collaborations with cryoEM laboratories, and experience in structural biology and/or in investigating aspects of eukaryotic translation and associated quality control processes is therefore desirable. Candidates should be highly motivated, be able to work independently and show excellent critical thinking, scholarly ability and communication skills.
These positions are available immediately, and carry a starting salary of $45,000 – $50,000 (depending on experience) plus health insurance. To apply, please send a cover letter discussing your interest in a position and mentioning the expected availability date, your curriculum vitae (with a summary of research experience, including techniques and methods used, and a list of publications) and contact information for three references to: