The University of Regensburg with its over 20,000 students is an innovative and interdisciplinary university, which provides a broad variety of research projects and disciplines. The Institute of Biochemistry, Genetics, and Microbiology, Chair of Biochemistry, Professor Meister, at the University of Regensburg is offering positions as
PhD student or postdoc with a strong background in biochemistry/molecular biology.
Our research focuses on the various functions of human non-coding RNAs in gene regulation. We use biochemical and molecular biological approaches to dissect non-coding RNA pathways. In particular, we characterize regulatory processes guided by microRNAs, circRNAs or lncRNAs and in addition we analyze protein components of these pathways. Furthermore, we study RNA base modifications (e.g. m6A) and their roles in gene expression. We perform deep sequencing studies to identify such modifications under different conditions as well as structure-function experiments to characterize writer, reader and eraser enzymes that are involved in such pathways. We routinely characterize RNA-protein interactions using various experimental approaches including X-ray crystallography and molecular biological or biophysical strategies. Modern Cryo-electron-microscopy is used for structural analysis and can be learned and applied.
Candidates should hold a Master/Diplom/PhD or equivalent in Biochemistry, Molecular Biology or a closely related subject.
We expect good communication skills, high motivation, dedication to molecular life sciences and the willingness to work in a competitive research field.
We offer a state-of-the-art biochemistry lab in an international environment with a long-standing experience in non-coding RNA biology. Well-equipped mass spectrometry, protein purification as well as deep sequencing platforms are available. A cryo-electron-microscope will be installed in the near futuer. The lab is generously funded by several national and international grants including an ERC consolidator grant. The successful candidate will be embedded into the international graduate school RIGEL.
The University of Regensburg is committed to the compatibility of family and career (for more information, please visit http://www.uni-regensburg.de/equal-opportunities). Severely disabled applicants are given preference in instances where applicants demonstrate an equal level of qualification. Please mention any severe disabilities, if applicable, in the application. Unfortunately, we do not provide reimbursement for expenses associated with interviewing.