A postdoctoral position is immediately available in Anders Byström’s laboratory at the Department of Molecular Biology, Umeå University, Sweden. Our lab is using a combination of genetics, biochemistry and molecular biology to study the biosynthesis and function of modified nucleosides in tRNA and mRNA. Defects in the formation of several RNA modifications are linked to human disease. We are predominantly using Saccharomyces cerevisiae as the model organism and we have shown that the lack of specific modifications in tRNA leads to pleiotropic cellular phenotypes including defects in G1/ S transition, vesicular trafficking, telomeric gene silencing, and DNA check point control. In our on-going work we are investigating the mechanisms by which RNA modifications modulate gene expression.
Required qualifications are a PhD degree or equivalent with a documented background in RNA biology. Previous experience in yeast genetics and analysis of RNA modifications is an advantage. Applications should be written in English, comprise of a cover letter with a brief statement of research interests, CV with a publication list and contact information of at least two referees. Documents should be in MS Word or PDF format and submitted via e-mail (firstname.lastname@example.org).
This position is a full-time, 12 month scholarship appointment with an opportunity for renewal based on performance and funding. Informal inquiries regarding this position are welcome.