The Single Molecule Imaging Group, led by Professor David Rueda, at the MRC London Institute of Medical Sciences (LMS), and the Department of Medicine at Imperial College London, is offering a 3-year Postdoctoral Position in Sigle Molecule Cell Biophysics.
We have recently developed a fluorgenic RNA (Mango) aptamer-based approach to image individual RNA molecules in live cells (Autour et al 2018 Nature Communications and Cawte et al 2019 in revision). We now seek a postdoctoral researcher to further exploit this technique to image various RNA processing mechanisms, such as gene expression, RNA splicing, RNA localization and RNA decay in live mammalian cells. Using this approach, we aim to elucidate the mechanisms regulating these RNA processing steps.
You must have a PhD (or equivalent experience), with a strong background in biophysics, quantitative biology or related disciplines. Candidates should be familiar with several of the following techniques: fluorescence microscopy, mammalian tissue culture, RNA transcription and processing, programming (e.g., python, Matlab, Labview, etc), image analysis (e.g. ImageJ) and quantitative data analysis. Equally important are outstanding creativity and enthusiasm for interdisciplinary science. Excellent English communication skills (spoken and in writing) are required.
Interestged individuals must apply online: