A postdoctoral position is available in the Department of Microbial Pathogenesis and Immunology at Texas A&M Health Science Center to study post-transcriptional regulation of the innate immune response to bacterial infection.
We are looking for a motivated, hard-working researcher to join the NIH-funded lab of Drs. Kristin Patrick and Robert Watson. Our lab is uniquely positioned to pursue exciting biology at the host-pathogen interface, leveraging Dr. Patrick’s expertise in eukaryotic mRNA processing and Dr. Watson’s expertise in innate immunity and host-pathogen interactions. We have strong evidence that pre-mRNA splicing in a major regulatory node during the innate immune response to infection. We are interested in understanding how innate immune signaling influences splicing and how changes to the spliceosome (primarily at the level of post-translational modification of splicing regulatory proteins (SR/hnRNPs)) determine innate immune gene expression outcomes.
The position will require expertise in eukaryotic RNA biology with a skill set including, but not limited to: tissue culture, molecular biology techniques (cloning, RNA isolation, RT-qPCR, immunoprecipitation, western blotting, EMSA, ChIP/RIP), and fluorescent microscopy. Applicants with a background in pre-mRNA splicing/regulation of gene expression will receive additional consideration. This individual will be expected to independently conceive, troubleshoot and interpret experimental results while also working collaboratively in a dynamic, interactive environment.
Applicants should have a Ph.D. in Immunology, Genetics, Microbiology, Molecular Biology, Biochemistry, or a related field, outstanding interpersonal skills, a strong work ethic, and a passionate enthusiasm for host-pathogen interaction/innate immunity research.
Applicants should submit a cover letter, describing ones background and goals, a CV, and contact information for 3 references (at the end of your CV) to the URL below. Questions can be directed to the lab email at firstname.lastname@example.org. Position will remain open until it is filled. Start date is flexible. Visit our website for more info about the lab: www.thepatrickwatsonlab.com