A Post-Doctoral Position To Study Mechanisms Of Translation And Translation-Associated Quality Control Processes In Eukaryotes

A postdoctoral research position is available in the laboratory of Tatyana Pestova and Christopher Hellen at the State University of New York Downstate Medical Center in Brooklyn, NY, USA. Our NIH-funded research uses state-of-art biochemical and molecular biology approaches to characterize molecular mechanisms of (1) canonical and non-canonical modes of translation initiation in mammals, including IRES-mediated initiation, (2) physiologically important specific cases of translational regulation, (3) translation elongation, termination and ribosome recycling, and (4) events downstream of termination, with a major focus on quality control processes, including mRNA surveillance and ribosome-associated quality control.

Required qualifications strictly include a Ph.D. in Molecular Biology/Molecular Biochemistry, and practical experience in RNA and/or protein biochemistry, including the expression and purification of native/recombinant proteins and the functional analysis of proteins and RNA-protein complexes. Experience in investigating aspects of eukaryotic translation and associated quality control processes will be highly appreciated. Our research involves active collaborations with leading cryoEM laboratories, and experience in structural biology would therefore be helpful.  Candidates should be highly motivated, be able to work independently and show excellent critical thinking, scholarly ability and communication skills.

These positions carry a salary of $45,000 – $60,000 (depending on experience) plus benefits, including health insurance. Review of applications will begin immediately until the positions are filled. To apply, please send a cover letter discussing your interest in a position and mentioning the expected availability date, your curriculum vitae (with a summary of research experience, including techniques and methods used, and a list of publications) and contact information for three references to:




As an Equal Opportunity / Affirmative Action employer, the Research Foundation will not discriminate in its employment practices due to an applicant’s race, color, religion, sex, national origin and veteran or disability status. Personnel are chosen on the basis of ability without regard to Race, Color, Religion, Sex, Age, National Origin, Disability or Marital Status in Accordance with Federal and State Law.