CNRS tenure-track position 2024 “RNA Modifications” Centre for Integrative Biology Toulouse, France

Posted on December 26,

The French National Center for Scientific Research (CNRS) opens tenure-track positions/Junior Professor Chairs (CPJ) in selected host institutes in France to recruit outstanding early career candidates. The chair package includes an up to 5-year senior researcher contract plus a minimum 300 k€ seed funding. A permanent position as a CNRS Research Director is foreseen at the end of the contract. A call for a CNRS tenure-track position on the theme of “RNA modifications” should be launched in March 2024, with the CBI as host institute.  

Outstanding early career candidates are welcome to apply. The candidates must hold a PhD and have demonstrated their ability to carry out original, groundbreaking research, as evidenced by high-level publications and international visibility, to develop independent research, and to meet the criteria for a successful application for national and international funding (ANR, ERC or equivalent).

The Centre for Integrative Biology of Toulouse (CBI, http://cbi-toulouse.fr/eng/) hosted by the University of Toulouse and the French National Centre for Scientific Research (CNRS) is located in Toulouse, south-west France, on the main Toulouse Paul Sabatier University campus (http://www.univ-tlse3.fr/). The University offers curricula in science, health, engineering, and technology, representing one of the most important scientific research clusters in France. The CBI currently brings together more than 400 staff in 42 internationally recognized research groups, performing research in fundamental aspects of the structure and function of complex biological systems. Research at the CBI covers all scales from individual molecules to whole organisms and animal groups. It is multidisciplinary, combining a wide range of research from genetics, epigenetics and RNA biology to microbiology, cell biology, chromatin dynamics, developmental biology, neurobiology, collective animal behavior, as well as computational and systems biology.

The RNA biology research program of the CBI (https://cbi-toulouse.fr/eng/pics-rna) has been at the leading edge of epitranscriptomics for several decades, with the pioneer discovery of site-specific rRNA modification (ribose methylations and pseudouridylations) guided by antisense small nucleolar RNAs and the identification of a plethora of small RNA guides and their function in complex organisms. The RNA biology program involves 17 teams investigating various aspects of genome organization and gene expression with emphasis on the synthesis and function of RNPs and RNA processing, modification and decay pathways, the function of small and long non-coding RNAs involved in gene expression and cell signaling, as well as the molecular machineries and enzymes involved in RNA metabolism. More recently, the importance of RNA m6A modifications in gene expression (mRNA stability and translation) and genome integrity (DNA repair) is actively investigated.

The package includes seed funding approaching 300 k€, free access to basic consumables, subsidized access to on-site technological facilities (photonic and (cryo-)electron microscopy, computer cluster for large data analysis), tissue culture rooms and animal facilities housing drosophila, zebrafish, xenopus and mice. Other cutting-edge facilities are accessible through an integrated local network of platforms (https://www.genotoul.fr/en/). The candidate will have the opportunity to develop independent research projects in a collaborative and international scientific environment, in an atmosphere fostering equality, diversity and inclusivity. He or she is expected as part of the CPJ contract to teach some courses in RNA research field in French or English. This contract will ultimately offer a permanent position as a CNRS Research Director.

For more detailed information, candidates may contact Anthony Henras ([email protected]), Simon Lebaron ([email protected]), Jérôme Cavaillé ([email protected]) or Kerstin Bystricky ([email protected]).