Biologist - RNA Biology, Mouse Genetics, Molecular biology

Posted on September 27,

A Biologist position is immediately available in the laboratory of Dr. Vidigal, Center for Cancer Research, NCI, NIH. The Vidigal lab aims to understand how small RNA pathways centered on Argonaute (AGO) proteins regulate mammalian physiology with a strong focus on mouse genetics. Current projects seek to define the regulation of AGO proteins in vivo and the mechanistic details through which they impact mouse development, homeostasis, and disease. In an exciting new area of research, the Vidigal lab is exploring how the functions of AGO2 are regulated between proliferating and quiescent cells as well as the requirement for direct RNA cleavage by AGO2 in quiescence through its conserved but poorly understood catalytic domain. The candidate will take on a leadership role helping the PI in the daily management of the lab (including overseeing the mouse colony) and with critical administrative tasks such as ordering, animal protocols, and budget management. The successful candidate will lead an independent project and collaborate with other researchers in the lab as needed.

The ideal candidate will have significant expertise working with mouse models and will be highly trained in molecular and cellular biology techniques, particularly those pertinent to RNA biology. The successful candidate should be familiar with or aware of current Next-Gen sequencing approaches and should enjoy developing/establishing those techniques to assist colleagues in the lab with their research efforts. Candidates will participate in lab meetings and journal clubs and will contribute both to the execution of experiments and to the intellectual development of ideas and projects. Demonstrated proficiency will be evidenced by relevant publications in peer-reviewed journals.

To apply to this position, please send your CV and the email contact of 3 references to [email protected] with the subject “Biologist Position”.