EMBO conference: Eukaryotic RNA turnover

Recent research has shown that RNA decay makes major contributions to biological regulation and cellular surveillance in eukaryotes. Fundamental RNA turnover pathways now being studied at the atomic level are conserved among yeasts, animals and plants, while each system also exhibits diversification. Central themes include regulation of mRNA turnover by AU-rich elements, and the effects of microRNAs on RNA decay and translation. In addition, numerous mechanisms eliminate RNAs that fail quality control checkpoints. This EMBO conference will also be a major forum for discussion of the latest findings relating to altered RNA turnover in disease, and the identification of potential therapeutic targets.

Session topics:

  • The machinery of RNA turnover
  • RNA quality control
  • RNA turnover and regulation of gene expression
  • miRNA-mediated mRNA regulation
  • Trans-acting factors and mRNA turnover
  • Global regulation of RNA turnover
  • RNA turnover and disease
  • 5′-3′ RNA turnover
  • Regulation of mRNA turnover

Stefan Ameres, Institute of Molecular Biotechnology, Vienna, Austria.
Cecilia Arraiano, Universidade Nova de Lisboa, Portugal.
Cécile Bousquet-Antonelli, University of Perpignan, France.
Mordechai Choder, Technion, Haifa, Israel.
Christine Clayton, University of Heidelberg, Germany.
Elena Conti, Max Planck Institute of Biochemistry, Martinsreid, Germany.
Myriam Gorospe, NIH, Baltimore, USA.
Pam Green, University of Delaware, USA.
Helge Grosshans, Friedrich Miescher Institute, Basel, Switzerland.
Matthias Hentze, EMBL, Heidelberg, Germany.
Torben Jensen, University of Aarhus, Denmark.
Joanna Kufel, University of Warsaw, Poland.
Elisa Izaurralde, Max Planck Institute, Tübingen, Germany.
Jack Keene, Duke University, USA.
Mike Kiledjian, Rutgers University, USA.
Domenico Libri, CNRS / Institut Jacques Monod, Paris, France.
Chris Lima, HHMI / Sloan-Kettering Institute, USA.
Lynne Maquat, University of Rochester, USA.
Sarah Newbury, University of Sussex, UK.
Lori Passmore, MRC LMB, University of Cambridge, UK.
Sébastien Pfeffer, CNRS / University of Strasbourg, France.
David Port, University of Colorado, USA.
Olivia Rissland, University of Toronto, Canada.
Bertrand Séraphin, IGBMC, Strasbourg, France.
Georg Stoecklin, University of Heidelberg, Germany.
Stepanka Vanacova, CEITEC / Masaryk University, Brno, Czech Republic.
Lidia Vasilieva, University of Oxford, UK.
Steve West, University of Sheffield, UK.
Jeff Wilusz, Colorado State University, USA.

Scientific Organizers:
Chris Norbury, University of Oxford, UK.
Sarah Newbury, University of Sussex, UK.
Cecilia Arraiano, ITQB, Portugal.


Registration deadline: 28th April 2017.
Abstract submission deadline: 28th April 2017.
Chosen participants will be notified by 5th May, 2017. Payment deadline 5th May 2017.