5-year Wellcome Trust funded postdoc posts, Centre for Developmental Neurobiology, London, UK

Posted on February 17,

The HOUART lab, situated at the heart of LONDON, is seeking to appoint three postdoctoral research associates (PDRA) to join a 5-year WELLCOME TRUST-funded research programme aiming to understand the role of axonal splicing factors and intron retaining transcripts in neuronal maturation and degeneration. Our nervous system crucially relies on local fast decisions taken at synapses, long distance from the neuronal cell body. The mechanisms by which these decisions are spatio-temporally controlled remain obscure. Axonal splicing factors and intron-retaining mRNAs have newly been identified as key players in the process. We seek to understand the fundamental molecular and cellular roles they play locally in the dynamic control of neuronal connectivity, using animal models (zebrafish) and cell culture approaches.

The research programme will require expertise in zebrafish genetics, transcriptomics, proteomics, high-resolution (live and fixed) molecular imaging, and sophisticated computational analytical methods. We wish to appoint one PDRA with expertise in cutting-edge high-resolution/molecular imaging technologies, a PDRA with strong zebrafish neurobiology background and a PDRA with very strong protein/RNA biology experience.

Prof. Corinne Houart is a member and Deputy Head of the outstanding Centre for Developmental Neurobiology and MRC Centre for NeuroDevelopmental Disorders at King’s College London and attached member of the Francis Crick Institute. This rich research environment provides to the posts world-class research facilities.

Deadline for application 31st March 2021. For further information, please contact Prof. Corinne Houart, [email protected]

Apply at:  https://jobs.kcl.ac.uk/gb/en/job/013764/Research-Associate