http://www.rnasociety.org/employment Mon, 01 Mar 2010 06:44:20 GMT List of the RNA Society E-Jobs http://www.rnasociety.org/employment#124 A postdoctoral position starting in July 2010 is open in the laboratory of Nelson Lau, at Brandies University, in Waltham, MA, near Boston. We are looking for a candidate with a PhD and prior molecular biology and biochemistry experience, a record of publications, and some proficiency with bioinformatics. Skills with mouse genetics, Xenopus biology and tissue culture will also be highly considered. Our group studies basic gene regulation mechanisms by small RNAs and the RNA interference pathway in animals. Specifically, we are interested in dissecting the molecular mechanisms of Piwi proteins and piRNAs, and to compare their functions with microRNAs, siRNAs and Argonaute proteins. Candidates should send an email to nlau[at]brandeis.edu with a CV, list of publications, and three references. Mon, 01 Mar 2010 06:44:20 GMT http://www.rnasociety.org/employment/index/124 http://www.rnasociety.org/employment#123 Postdoctoral Researcher for international collaboration on functional plant RNA species We seek a postdoctoral fellow for research into the structure and dynamics of functional RNA species identified from plant cells. This will involve studies using FRET, single-molecule methods and other biophysical approaches. The work will be carried out in the laboratory of David Lilley at the University of Dundee, United Kingdom, in the Nucleic Acid Structure Research Group. This work is funded by the Human Frontiers Science Program for three years. It is a four-way collaboration between the laboratories of Philip Bevilacqua and Sally Assmann (Penn State University), François Major (Université de Montréal) and Dundee. The position is available immediately. Enquiries to Professor Lilley at d.m.j.lilley[at]dundee.ac.uk http://www.dundee.ac.uk/biocentre/nasg/ Tue, 09 Feb 2010 22:37:34 GMT http://www.rnasociety.org/employment/index/123 http://www.rnasociety.org/employment#122 BIOCHEMISTRY LABORATORY RESEARCH MANAGER AT STATE UNIVERSITY OF NEW YORK AT ALBANY Areas of research include studies of RNA/RNA and RNA/protein and RNA/small molecule interactions involved in the control of gene expression with applications to specific human health issues. The successful applicant will manage all aspects of the academic lab, maintain lab infrastructure related to the operation of an RNA specialized lab. The duties will include, but will not be limited to, ordering lab supplies and consumables, maintaining biochemical techniques particular to the lab, maintain and organized lab environment, supervising and training students, assisting in manuscript and grant writing, and conducting an independent project. Applicants should have a masters degree in biochemistry, molecular biology, biology, chemistry or related field with demonstrated experience in separation science (HPLC, gel electrophoresis), biochemical assay techniques and biochemical instrumentation (UV, CD, MS and fluorescence spectroscopy, and microcalorimetry) and supervison/lab management. Preferred two years of research/lab management experience beyond the masters degree. The successful applicant will have demonstrated independence, and experience in supervision of others. Applicants must address in their letter of application their specific ability to work with culturally diverse populations. This is a state-funded 12 month calendar year position beginning May 1, 2010 that is renewable but does not qualify for a permanent appointment. Salary dependent on qualifications and experience - $45,000 max. Respond with full curriculum vitae, statement of research experience and interest, and contact information for three references. Please apply online via https://albany.interviewexchange.com/jobofferdetails.jsp?JOBID=16819 Tue, 09 Feb 2010 22:25:37 GMT http://www.rnasociety.org/employment/index/122 http://www.rnasociety.org/employment#121 We are seeking to appoint two Postdoctoral Research Assistants to NIH-funded research programs to study the mechanism of protein synthesis in higher eukaryotes. Current research projects concern (1) the mechanism of translation initiation by the canonical scanning mechanism (EMBO J. 27: 1609-21) (2008); Cell 135: 1237-50 (2008), (2) mechanisms of IRES-mediated initiation on viral mRNAs (EMBO J. 27: 1060-72 (2008); Proc Natl Acad Sci 106: 9197-202 (2009) and (3) translation termination and ribosome recycling (Cell 125: 1125-36 (2006); Cell 131: 286-99 (2007; Molecular Cell 37: 196-210). These projects use a combination of biochemical and molecular biology approaches. Research will be conducted in the laboratories of Dr. Christopher Hellen and Dr. Tatyana Pestova in the Dept. of Cell Biology, State University of New York Downstate Medical Center, Brooklyn NY (http://www.downstate.edu/cellbiology/). The preferred start date is March 1st 2010. Applicants are expected to be highly motivated and with excellent critical thinking skills. They should have a PhD or an equivalent qualification, and a strong background in biochemistry and molecular biology, with experience in protein purification, RNA analysis and characterization of protein structure/function. Applicants should submit (preferably by email) a detailed Curriculum Vitae, the names and contact information of three referees (one of whom must be the current or most recent employer), and a cover letter describing their research interests. Tue, 09 Feb 2010 22:22:42 GMT http://www.rnasociety.org/employment/index/121 http://www.rnasociety.org/employment#120 Non-coding RNAs turn out to have crucial roles in cancer development. After the discovery of microRNAs as oncogenes and tumor suppressors, long non-codingRNAs of various origins are now also being implicated in carcinogenesis. Using an in vitro model of human cell transformation, we have identified several ncRNAs that affect this process. Their characterization will be an interesting and exciting challenge! A position for a talented and enthousiastic postdoc is available, starting in the coming year. If you have experience with RNA-biology (beyond shRNA or microRNA expression and detection) and want to experience the emerging scientific hub in Singapore, check out the website of the lab of Molecular Tumor Genetics at the Duke-NUS Graduate Medical School (www.voorhoevelab.com) Tue, 09 Feb 2010 22:20:03 GMT http://www.rnasociety.org/employment/index/120 http://www.rnasociety.org/employment#119 A postdoctoral position in RNA structural biochemistry is open in my lab at the Department of Cell and Molecular Biology at the Karolinska Institutet in Stockholm. Successful candidates will participate in all steps involved in structure determination of RNA-protein complexes relevant to tRNA biogenesis. Suitable candidates have a PhD in a relevant area, preferably in RNA biochemistry, structural biology or closely related subjects. A general requirement to be eligible for this position is a recent doctoral degree from a University outside Sweden. The position is available from 1st of February and for at least two years. The application should contain a cover letter and a CV with publication list. Send the application as an email with attachments to Martin.Hallberg[at]ki.se Mon, 04 Jan 2010 08:13:09 GMT http://www.rnasociety.org/employment/index/119 http://www.rnasociety.org/employment#118 A Post-Doctoral position is available immediately in the laboratory of Dr. Alex Moreira and Dr. Alexandre Carmo to work on the project "NANOFOL - Folate-based nanobiodevices for integrated diagnosis/therapy targeting chronic inflammatory diseases", FP7-NMP-2008-LARGE-2 (FP7 NMP-2008-4.0-1). We are looking for highly motivated candidates with experience in at least one of the following: transfection and expression in eukaryote systems; RNA interference; flow cytometry; biochemistry of signal transduction/cell activation; RNA techniques. Experience in knockout or transgenic animals is advantageous as well. The ideal candidate will hold a Ph.D. in in the fields of Biomedicine, Biology, Biochemistry, Molecular Biology or related areas. NANOFOL proposes to develop a new diagnostic/therapy approach using folate based nanobiodevices (FBN) able to provide a new type of cost efficient treatment for chronic inflammatory diseases such as Atherosclerosis (AS) and Rheumatoid Arthritis (RA) with low side effects that will constitute a more advantageous solution than current therapies. In the CAGE group, the successful candidate will be responsible for: establishing culture conditions for in vitro activation of peripheral blood (PB)-derived monocytes/macrophages and macrophage cell lines; analysing siRNAs stability, release and effect in activated macrophages; evaluating the lipophilic drugs’ release and physiological effect in activated macrophages; in vivo testing of FBN in animal models of RA and AS. The initial appointment will be for one year, renewable for up to a maximum of 4 years. The applications should be received between November 30th and December 18th, 2009. Proposals must include a letter of motivation, CV, and 2 letters of reference, and should be sent to Dr. Alexandre Carmo (acarmo@ibmc.up.pt; amcarmo[at]ibmc.up.pt). Employment at the IBMC is regulated by current laws relating to the Statute of Science Research Fellows, namely Law 40/2004 of August 18, and the Regulation of Scientific Research Studentships of the IBMC (www.ibmc.up.pt/fellowships.php). Thu, 10 Dec 2009 19:24:51 GMT http://www.rnasociety.org/employment/index/118 http://www.rnasociety.org/employment#117 A Post-doctoral position is available in the laboratory of Dr. Livio Pellizzoni at Columbia University to study the biogenesis and function of ribonucleoprotein complexes as well as the role of RNA dysfunction in the pathophysiology of inherited human motor neuron diseases. The research project will focus on the identification of genetic modifiers of the expression and function of SMN, the Spinal Muscular Atrophy (SMA) disease gene product, using genome-wide RNAi. The candidate must hold a Ph.D. in the biological sciences and have strong laboratory expertise in biochemistry, molecular and cellular biology. Prior experience working with RNA-protein complexes is desired. Candidates should submit electronically a cover letter with a description of scientific interests and career goals, detailed curriculum vitae, and contact information for three references. The anticipated start date for this position is February 2010. The initial appointment is for one year with the possibility of extension for additional years based on performance and availability of funds. Wed, 02 Dec 2009 10:07:07 GMT http://www.rnasociety.org/employment/index/117 http://www.rnasociety.org/employment#116 A postdoctoral position is available in the lab of Rick Russell to investigate folding of large RNAs and the mechanisms of DEAD-box RNA chaperone proteins by using biochemical and biophysical approaches. Applicants must have a PhD in biochemistry or a related field and have experience in performing quantitative studies of RNA. Experience in working with proteins is preferred but not essential. The initial appointment will be for one year with the expectation of renewal. Interested candidates should send a CV and the names of three references to rick_russell[at]mail.utexas.edu Wed, 02 Dec 2009 10:02:09 GMT http://www.rnasociety.org/employment/index/116 http://www.rnasociety.org/employment#115 I am anticipating a postdoctoral position opening in March 2010 (possibly earlier) in my lab at the University of Texas at Austin. We study nuclear export and maturation of ribosomes in yeast. We are particularly interested in the final steps of assembling a functional ribosome, the mechanisms that release the export factors and the interface between ribosome biogenesis and translation. Applicants must have a PhD degree in Biochemistry or Molecular Biology or a related field and have experience in protein purification and RNA analysis. Prior experience in ribosome biochemistry or translation is preferred. The initial appointment will be for one year with the expectation of renewal. Interested candidates should email a cover letter, CV, and contact information for three references to Dr Arlen Johnson at arlen[at]mail.utexas.edu. http://www.bio.utexas.edu/faculty/ajohnson/ Mon, 09 Nov 2009 08:22:47 GMT http://www.rnasociety.org/employment/index/115