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Postdoctoral Position in Bacterial RNA Biology at Uppsala University

A postdoctoral position is available in the laboratory of Erik Holmqvist at Uppsala University in Sweden to study post-transcriptional gene regulation by bacterial RNA binding proteins and small RNAs in the context of host cell infection. We combine molecular biology, biochemistry, and genome-wide analyses such as CLIP-seq and RNA-seq to investigate molecular mechanisms and their consequences for bacterial physiology and virulence.

We are looking for a highly motivated, bright and enthusiastic candidate with a background in RNA biology, infection biology and/or molecular microbiology. The candidate should be able to work as a team member, learn new skills rapidly, and have excellent communication skills. The applicant must have received his/her PhD degree from a non-Swedish institution within the last 5 years.

The Department of Cell and Molecular Biology at Uppsala University, Sweden, consists of seven different research programs. Research focuses on the chemical, molecular and structural backgrounds of cellular processes. Several laboratories at the department are also centres of excellence: Structural Biology, Molecular Biophysics, Protein Synthesis, and Uppsala RNA Research Centre.

Please send your application (in English language) including a CV, a short summary of academic records and research interests, and at least two letters of recommendation (or contact details of potential referees) to erik.holmqvist@nullicm.uu.se

Anticipated start date: October/November 2016. Salary according to EMBO standard.

Tenure-track Biochemistry Faculty Member at the Assistant Professor Level

The Department of Chemistry and Biochemistry at the University of Oregon invites applications for a tenure-track Biochemistry faculty member at the Assistant Professor level to begin in Fall 2017 or later. Biochemistry research at the University of Oregon takes place in the Institute of Molecular Biology (molbio.uoregon.edu), which promotes interdisciplinary interactions between life science researchers in the departments of Chemistry and Biochemistry, Biology and Physics.

We seek applicants from all areas of molecular biology who are using advanced approaches to study mechanisms of cellular function, including topics in RNA biochemistry. A Ph.D. is required. New faculty will join a rich and collaborative atmosphere with existing strengths in host-pathogen interactions, stem cell biology, organelle biogenesis, genome function, and cytoskeleton biochemistry. Successful candidates will have the potential for establishing an outstanding independent research program and excellence in teaching at the undergraduate and graduate levels. They will also support and enhance a diverse learning and working environment.

To assure full consideration, application materials should be received by October 10, 2016. Please apply at https://academicjobsonline.org/ajo/jobs/7667 and upload a cover letter, curriculum vitae, a statement of research plans and objectives, and a brief statement of teaching philosophy or interests. The candidate should also arrange for three letters of recommendation to be uploaded directly by the recommenders. Review of application materials will continue until the position is filled.

The University of Oregon is an equal opportunity, affirmative action institution committed to cultural diversity and compliance with the ADA. The University encourages all qualified individuals to apply, and does not discriminate on the basis of any protected status, including veteran and disability status.


National Institute of Diabetes and Digestive and Kidney Diseases
National Institutes of Health
Department of Health and Human Services

A tenure track or tenure-eligible position is available for an individual who is interested in developing an independent research program, or has a demonstrated track record of research excellence, in an area of modern mechanistic molecular biology. Current research in this laboratory includes such diverse areas as chromatin-based gene regulation, DNA recombination and repair, bacterial cell division, muscle development, protein trafficking, and structural biology in a wide spectrum of systems.

The laboratory is located on the main campus of the NIH in Bethesda, Maryland, just outside of Washington, DC. This Laboratory (http://www.niddk.nih.gov/research-funding/at-niddk/labs-branches/LMB/Pages/about.aspx) is part of the intramural program of the National Institute of Diabetes and Digestive and Kidney Diseases (http://www.niddk.nih.gov/research-funding/at-niddk/labs-branches/Pages/default.aspx) and provides a highly interactive environment with expertise in molecular, cellular, biochemical and biophysical techniques. NIDDK supports a wide range of basic biomedical research, including several state of the art core facilities. The NIH intramural research program offers many advantages, including stable funding, the ability to do high risk research, and access where desired to clinical collaborators.

Applicants must have a Ph.D., M.D., or equivalent doctoral degree and have demonstrated expertise and a record of achievement. Applicants may be U.S. citizens, resident aliens, or non-resident aliens with, or eligible to obtain, a valid employment-authorization visa. Interested applicants should submit a Curriculum Vitae and list of publications, copies of no more than 5 publications, and a separate document that combines a summary of graduate and postdoctoral research accomplishments with a plan for future research. Senior applicants should also mention independent research accomplishments. Numerical indices such as impact factors or citation numbers will not be taken into consideration, and should not be included in the application. Applicants should also have three letters of reference submitted. All material should be emailed as pdf files to: Dr. Gisela Storz, Chair, Laboratory of Molecular Biology Search Committee
C/O Linda Robinson
The review of applications will begin on or around September 1, 2016. Applications will be accepted until the position is filled. Salary and benefits are commensurate with the experience of the applicant.


Georgetown University School of Medicine Full-time, Tenure-track Faculty Position

Georgetown University School of Medicine, Department of Oncology invites highly qualified applications for a full-time, tenure-track faculty position with competitive salary, spacious research facilities, and substantial start-up funds.

Applicants are expected to conduct basic research in oncology and develop independent research programs supported by peer-reviewed grant funding. Participation in teaching for the School of Medicine and the Tumor Biology graduate program are required but percent effort for teaching will be adjusted based on the productivity and funding level of the investigator. The faculty member is expected to demonstrate scholarly activities by engaging in leadership of services beneficial to the Department, University, and the scientific community.

All applicants must have a M.D. or Ph.D. degree (or equivalent) and at least three years of postdoctoral experience. The area of research should complement existing departmental strengths in cancer biology including transcription regulation, splicing mechanisms, signal transduction, protein biochemistry, and molecular mechanisms of metastasis. Preference will be given to candidates interested and able to investigate small molecule-protein interactions for therapeutic development.

Interest in sarcoma, leukemia and brain tumor models is important but not required.
Evidence of past high quality research is required. The candidate needs to show potential for extramural funding and publication in scientific journals. Clinical practice is possible and negotiable, but not required for M.D. candidates. Absolute clear and protected research time will be provided in the case of clinical practice. Salary will be commensurate with education, experience and established School of Medicine guidelines.

Effective Date of Appointment: After January 1, 2017, as late as June 30, 2017.

Application Deadline: October 1, 2016 or until filled.

Applicants should submit (i) curriculum vitae, (ii) description of research, (iii) teaching interests, and (iv) arrange to have at least three letters of reference sent to (email is preferred):

Jeffrey A. Toretsky, M.D.
Department of Oncology and Pediatrics
Lombardi Comprehensive Cancer Center
Georgetown University
3970 Reservoir Rd, NW
New Research Building, Room E316
Washington, DC 20007

Email: sarcomalab@nullgeorgetown.edu

Post-doctoral Position at Rice University

A post-doctoral position is available immediately in the laboratory of Dr. Ed Nikonowicz in the BioSciences Department at Rice University in Houston, Texas. The initial appointment is for one year and can be extended for additional years. The project involves structural and functional studies of RNA-mediated gene regulation with an emphasis on understanding the contributions of select tRNA nucleobase modifications to gene activity and cell fitness. An interdisciplanry approach utilizing genetic and biophysical methods will be used to correlate in vitro and in vivo measurements.

The applicant should have a PhD in Biochemistry, Microbiology, or related field, good quantitative skills, and expertise in molecular and biophysical techniques. A strong interest in RNA research is required. Rice University is located adjacent to the Texas Medical Center, home to several research institutions including UT Medical School, Baylor College of Medicine, and MD Anderson Cancer Center.

To apply, please submit a CV and provide the names of two references to edn@nullrice.edu.

Rice University is committed to affirmative action and equal opportunity in education and employment. Rice does not discriminate on the basis of race, color, religion, sex, sexual orientation, gender identity, national or ethnic origin, age, disability or veteran status. Rice University is an Equal Opportunity/Affirmative Action Employer.

Post-doctoral Position in the Laboratory of Dr. Ed Nikonowicz

A post-doctoral position is available immediately in the laboratory of Dr. Ed Nikonowicz in the BioSciences Department at Rice University in Houston, Texas. The initial appointment is for one year and can be extended for additional years. The project involves structural and functional studies of RNA-mediated gene regulation with an emphasis on understanding the contributions of select tRNA nucleobase modifications to gene activity and cell fitness. An interdisciplanry approach utilizing genetic and biophysical methods will be used to correlate in vitro and in vivo measurements.

The applicant should have a PhD in Biochemistry, Microbiology, or related field, good quantitative skills, and expertise in molecular and biophysical techniques. A strong interest in RNA research is required. Rice University is located adjacent to the Texas Medical Center, home to several research institutions including UT Medical School, Baylor College of Medicine, and MD Anderson Cancer Center.

To apply, please submit a CV and provide the names of two references to edn@nullrice.edu.

Position as PhD Student (Three Years)

A position as PhD student (three years) is announced for the junior group ‘Non-coding RNAs in cardiovascular and neoplastic disease’. The focus of the work will be on the identification of medium-sized non-coding RNAs, which show a deregulated expression in neoplasias (especially renal cell carcinoma). Promising RNA candidates will be selected and further validated in suitable cell culture models. The aim of this project is to elucidate the role of medium-sized RNAs in neoplastic disease and to establish novel diagnostic markers/therapeutic targets.

Required skills:
Master of science or equivalent in life science (e.g. biology, biochemistry)
Interest for basic biomedical research
Basic knowledge on methods in biochemistry and molecular biology (e.g. cloning, Western Blot)
Experience in RNA biology (RNA isolation, Northern Blot, RT-qPCR)
Experience in mammalian cell culture
Knowledge on animal work is preferred
Experience in bioinformatics (NGS-data)

Please send your application via mail to Dr. Marcel Köhn (marcel.koehn@nullmedizin.uni-halle.de) until the 19th of August 2016. The project start is scheduled for October/November 2016.

Post-doctoral Position at the Central-European Institute of Technology (CEITEC)

CEITEC is a scientific centre in the fields of life sciences, advanced materials and technologies whose aim is to establish itself as a recognized centre for basic as well as applied research. CEITEC offers a state-of-the-art infrastructure and great conditions to employ excellent researchers.

A post-doctoral position is available at the Central-European Institute of Technology (CEITEC), Brno, Czech Republic, in the group of Mary O‘Connell. This work is funded by the ERA Chair grant. The project focuses on how modification in RNA is used by the innate immune system to discriminate ‘self‘ from ‘non-self‘ (Mannion et al., Cell Reports. 2014; http://dx.doi.org/10.1016/j.celrep.2014.10.0).

The successful candidate will join a team of motivated researchers who are investigating the proteins and RNA involved in this novel innate immune pathway. We also want to elucidate and identify mutations in this pathway that result in autoimmune disorders. We use a variety of different models in our investigations; Drosophila, mice and stem cell culture.

The candidate should be highly motivated, self-driven and passionate about science with a solid publication record. A PhD degree in either molecular biology, biochemistry, immunology, mouse genetics, stem cells is required. Applicant should have a strong background in standard molecular biology and biochemistry techniques. Good communication and interpersonal skills and fluency in spoken and written English are required. Expected start date is preferably autumn/winter of 2016 or after upon agreement.

We offer:
We offer a competitive salary that will be based on the candidate`s qualifications and experience.

Anticipated start date: November 2016

Please send the application (including CV, short statement of research background / interests and the contact information of at least three references) by e-mail to recruitment@nullceitec.muni.cz

Please quote the “PostDoc ERA Chair” in the subject.

Electronic application deadline is: September 16, 2016

Information about Brno, Czech Republic
• The capital of South Moravian Region and the second largest city in the Czech Republic with a population of almost 400,000 people
• Modern, dynamic and fast growing centre of industry, trade, science, research and innovation with business incubators and centres of excellence in science
• A city of universities with more than 86,000 students
• More than 10,000 researchers; 2,200 IF publications/year; 600+ PhD graduates/year
• 500 mil. EUR of R&D investment per year, more than 350 companies with in-house R&D
• City of Gregor Mendel, the founder of genetics; the prestigious Mendel Lectures series takes place in Brno since 2003 (lectures of the world´s top scientists, including Nobel Prize winners)

For further information about:
• CEITEC, please visit www.ceitec.eu
• CEITEC Welcome Office, please visit http://www.ceitec.eu/ceitec-welcome-office/t1137
• Masaryk University, please visit www.muni.cz
• Brno, please visit http://www2.brno.cz/index.php?lan=en&nav01=20608&nav02=20617


Department of Biochemistry and Molecular Biology at University of Texas Medical Branch

A post-doctoral fellow position starting fall 2016 is available in the laboratory of Dr. Muge Kuyumcu-Martinez to study post-transcriptional gene regulation by RNA binding proteins in normal and diseased hearts. We utilize inter-disciplinary approaches that combine mouse genetics, cell biology, genome editing, biochemistry, and genome-wide analyses (e.g. RNA-seq and CLIP-Seq) to investigate molecular mechanisms that dictate post-transcriptional decisions in the heart.

We are looking for a highly motivated, bright and enthusiastic candidate with a background in RNA biology, heart development or cardiac physiology. The candidate should be to able to work as a team member, learn new skills rapidly, and have excellent communication skills. It is highly desirable that the applicant received his/her PhD degree within the last 2 years.

University of Texas Medical Branch located in Galveston island is a part of the Texas Medical Center, which is the largest medical complex in the world comprised of 54 highly collaborative and interactive medically oriented institutions.

If you are interested, please provide your curriculum vitae, a statement of career interests (1 paragraph long), and contact information for three references to nmmartin@nullutmb.edu.

Two Postdoctoral Positions Available in RNA Structural Biology in The RNA Institute in NMR and Mass Spectrometry

Two Postdoctoral Positions are available in RNA structural biology in The RNA Institute in NMR and Mass Spectrometry. The Institute is developing cutting edge technology for the advancement of RNA therapeutics and diagnostics in infective disease (viral and bacterial and diabetes), as well as basic understandings of RNA biology in puripotent stem cell differentiation and the effects of cannabinoids and bis-phenol-A. We are looking for a bright and enthusiastic individuals who seek answers and travels beyond known boundaries.

(1) A Post-Doctoral Associate position is now open in the lab of Dr. Paul F. Agris within The RNA Institute of the University at Albany (SUNY). Applicants are sought with expertise in modern high-field NMR instrumentation for determination of macromolecular structure, RNA, RNA-RNA, RNA-protein and small molecule interactions in infective disease and in diabetes. Applicants must also have experience in molecular biology/biochemistry with experience in RNA preferred.
(2) A Post-Doctoral Associate position is now open in the RNA Institute with Dr. Maria Basanta Sanchez in analytical development of high-throughput methods to characterize RNA modifications, the epitranscriptome, from a wide variety of biological systems using Mass Spectrometry-based technologies. In addition research includes the development of high-throughput methods of RNA separation and purification and the use of chromatography to decipher RNA structure. Applicants are sought with expertise in small-molecule mass spectrometry; chromatographic separation techniques; statistical analysis of large data sets.

The positions require the ability to dissect problems and projects into manageable tasks; demonstrated organizational skills with the ability to handle multiple tasks with different priorities; ability to work on a team, yet demonstrate the skills of independence expected in career advancement; excellent oral and written communication skills. Foreign nationals must have a J1 visa with at least two years remaining to be a postdoctoral fellow in the US or an HIB. An H1B application will not be financially sponsored.

For the NMR position apply to pagris@nullalbany.edu with the subject line of NMR Postdoc Fellow and for the MS position apply to mbasantasanchez@nullalbany.edu. Include: letter of interest with date of availability, complete curriculum vitae with list of publications, statement of research experience in macromolecular NMR, or Mass Spectrometry and list of three or more contacts for letters of reference.

Postdoc positions to study evolution of gene expression

We are looking for two brilliant, motivated, and adventurous individuals to join the Shah Lab (theshahlab.org) at Rutgers University as postdoctoral researchers.

What we do:
We generate high-throughput genomic datasets and use computational models to study

  1. How patterns of gene expressions evolve and how various factors influence the dynamics of protein synthesis in cells.
  2. How epistatic interactions between mutations affect protein evolution.

What will you get to do:
We are not looking for someone to work on specific projects ongoing in the lab. Rather, you will have the freedom to work on your best ideas that are aligned with the lab’s research focus. You will also have several opportunities to collaborate with researchers both at Rutgers and elsewhere on your ideas and other projects of mutual interests. In addition, you will have opportunities to co-teach a class as well as mentor students, if you so desire.

Finally, you will get the resources and support to develop your own research program as you plan to move to the next stage of your career.

What is expected of you:
Good writing and speaking skills to communicate and convince others of your research ideas, and a drive to see them to completion. You should be willing to collaborate freely and be open to give/take constructive criticism. You should also be willing to teach/share tricks and tools you picked up in grad school with the rest of the group.

What to expect:
A fun, supportive environment – both in the lab and the Genetics department. Lab and office space in a fancy new-ish building and quiet workspaces when needed.
Coffee is serious business in the lab. You will have access to the finest beans from micro-roasters across the country for amazing espressos, lattes and pour-overs. Because we are an inclusive bunch, tea drinkers will also be tolerated.

Let’s face it, postdoc pay sucks. Salaries will be based on NIH scales with some flexibility depending on the funding level of the lab at the time. In addition to medical and life insurance you will also get not-too-shabby retirement benefits.

In addition to being your scientific mentor, my primary responsibilities would be towards your personal and professional growth. You will always find an audience to discuss opportunities and challenges, and a strong advocate for your interests.

Desired Qualifications:
A Ph.D. in evolution, genetics, or statistics. In rare cases we will also consider individuals with a Ph.D.  in mathematics or physics.

How to apply:
Fill out the form here – https://goo.gl/sNO5pq

Postdoctoral position at the interface of RNA and Chromatin in Colorado

A postdoctoral fellow position is available in the lab of Aaron M. Johnson at the University of Colorado School of Medicine in the Denver Area.  The research focus for this position is studying the molecular mechanism of non-coding RNA-mediated heterochromatin form and function using diverse cell and molecular biology approaches.  See www.AJLab.org for details.

Highly-motivated senior graduate students or current postdocs are welcome to apply.  The ideal candidate will have previous experience with basic molecular biology and mammalian tissue culture techniques. At least one first-author research publication from graduate school is an expectation.  This position is immediately available and grant-funded for up to five years; however, applications for postdoctoral fellowships will also be highly encouraged.

The Johnson Lab is located in the Department of Biochemistry and Molecular Genetics, a collegial group of scientists that believes that informality and idea-sharing are vital for a thriving scientific environment.  Recently, the University of Colorado School of Medicine has invested $20 million in an RNA Bioscience Initiative that will further advance RNA-focused research, broadly defined.  The Initiative will recruit additional faculty, provide grant and fellowship opportunities, and foster a broad spectrum of RNA science from bench to bedside.  See www.RNABio.CO for details.

Send e-mail inquiries for postdoc positions to: aaron.m.johnson@nullucdenver.edu

Attach a CV, including a list of three professional references.  Please include in the e-mail a description of your interest related specifically to the research of the lab.

Postdoctoral positions in RNA regulation at Sloan-Kettering, New York City

We seek motivated scientists with strong RNA background to be involved in our studies of post-transcriptional regulatory networks. Our laboratory at Memorial Sloan-Kettering Cancer Center combines experimental and computational approaches to discover and functionally elucidate small RNA biogenesis, mRNA processing, and regulatory networks that govern neural specification and function.

We have several ongoing projects available, including: (1) Elucidation of mechanism and biology of tailing and trimming pathways. (2) Genomics and genetics of RNA methylation pathways. (3) Developmental and behavioral analysis of miRNA knockouts. Each project has substantial unpublished molecular and genetic data that the candidate can take advantage of, primarily in the Drosophila system, but findings can potentially be extended into mammalian systems.

We have openings for 2 highly motivated postdoctoral fellows with broad interest in integrative strategies to join our team. Relevant candidates for the first two projects must have strong experience in studying RNA processing using cell culture, in vitro approaches, and genomewide strategies. Relevant candidates for the third project require strong background in Drosophila genetics and neurobiological methods. Computational expertise is beneficial for all candidates. Positions are available immediately and funded for at least three years, contingent on performance. Please send letter of inquiry, CV and references to laie@nullmskcc.org.

Recent publications on small RNA mechanisms and miRNA neural biology:
Garaulet, Developmental Cell 2014, Wen et al, Molecular Cell 2015, Bortolamiol-Becet, Molecular Cell 2015, Sun, PLoS Genetics 2015; Garaulet Journal of Neuroscience 2016.

University of California, Santa Cruz (UCSC) Postdoctoral Position

The University of California, Santa Cruz (UCSC) invites applications for a postdoctoral position in the laboratory of Assistant Professor Angela Brooks in the Department of Biomolecular Engineering. The successful candidate will participate in research to further elucidate the role of somatic transcriptome alterations that contribute to cancer phenotypes, with a focus on altered RNA splicing. The successful candidate will be expected to develop and implement computational methods on high-throughput sequencing data, play key roles in international research collaborations, and lead collaborative projects consisting of other computational and “wet lab” biologists. Candidates with a strong cancer and/or RNA biology background with a strong interest in developing computational expertise are also encouraged to apply.

BASIC QUALIFICATIONS: Ph.D. or equivalent in computational biology, computer science, mathematics, statistics, bioengineering, genetics, biochemistry, molecular biology, cell biology, or other relevant field; demonstrated excellence in academic research as evidenced by one or more peer-reviewed, submitted, or in-preparation first-author publications.

PREFERRED QUALIFICATIONS: Experience with high-throughput sequencing data analysis; strong interpersonal skills; experience leading a team or project; good written and verbal communication skills; strong interest in RNA biology and cancer biology.

POSITION AVAILABLE: As soon as possible

TERM OF APPOINTMENT: The initial appointment is for one year, with likely extension, contingent upon availability of funding and positive performance evaluation.

TO APPLY:  Please send a cover letter, CV, and three references to anbrooks@nullucsc.edu.

Postdoctoral position in the field of RNA biology and metabolism

The German Cancer Research Center (DKFZ) invites applications for a highly motivated and creative postdoctoral researcher to explore the posttranscriptional regulation of metabolism. The DKFZ is located in the picturesque city of Heidelberg in the South of Germany and benefits from an exceptionally strong research environment, with Germany’s oldest university and several other leading life science research institutions in Europe. The successful candidate will join the lab of Dr. Bruno Galy in the „virus-associated carcinogenesis unit“ of the DKFZ.

Metabolic remodeling is emerging as a key process of physiology and disease. Although posttranscriptional regulations play a key role in shaping proteomes, genetic control of metabolism has so far been mostly investigated at the level of transcription. The interconnection between metabolism and the complex life of a mRNA, from its synthesis to its translation and decay, remains poorly understood. Iron metabolism is an ideal model system to study the posttranscriptional regulation of metabolism. Indeed, iron homeostasis is maintained by two RNA binding factors called Iron Regulatory Proteins (IRPs). The IRPs respond to changes in cellular iron levels and in turn modulate the translation or turnover of target mRNAs encoding iron management proteins. In this postdoctoral project, we will use high-throughput approaches developed recently to define the regulatory scope of the IRP network on a system wide scale. This integrative approach will be carried out in vivo, using state‐of-the‐art IRP mouse models. With this work we wish to unveil new facets of a central homeostatic circuit in the cell, and establish a basis for the study of other gene regulatory networks with similar properties.

The applicant holds a Ph.D. (or equivalent degree) in biology, biochemistry or related field and an excellent publication record. He/She is expected to have a strong background in RNA biology. A solid experience with cell and molecular biology techniques and in particular high throughput approaches (e.g. ribosome profiling) will be essential; familiarity with standard bioinformatical analysis of large data sets is also required. The candidate is rigorous, able to conduct independent research, but also enjoys interacting with colleagues of different disciplines and nations. Good presentation skills and experience on project management (importance of scheduling, deliverables, reporting) will be highly valued.

Funding for a total of 3 years is available and the position is open immediately. Your application (in English language) must include a CV, a summary of academic records, your research interests, and at least two letters of recommendation (or contact details of potential referees). For further question, please contact Dr. Bruno Galy (b.galy@nulldkfz.de).

Department of Cellular and Molecular Physiology at Yale School of Medicine

A postdoctoral position is currently available in the laboratory of Carson Thoreen in the Department of Cellular and Molecular Physiology at Yale School of Medicine. The laboratory is seeking to understand how the mTOR pathway, a master regulator of growth, controls the translation and stability of mRNAs under normal and disease contexts. We employ a wide range of approaches that include deep-sequencing (eg. ribosome profiling), bioinformatic and classical biochemical strategies. Creative individuals with a PhD or MD, and preferably a strong background in biochemistry and/or cell biology and a quantitative bent, are encouraged to apply. Applicants should send a current CV to carson.thoreen@nullyale.edu.

Diseases of mRNA metabolism

The MMPU aims at strengthening the link between molecular research and medicine and consists of 8 international teams of molecular research-oriented MDs, PhDs, PhD students and technicians. The research philosophy aims at the molecular understanding of the basis of common human diseases, its applications in diagnosis and therapy, and feedback from ‘bedside medicine’ into the research laboratory.


You will be integrated into the MMPU team “Diseases of mRNA metabolism” which focuses on basic and translational aspects of mRNA metabolism in common diseases such as the hemoglobin disorders, thrombosis and inflammation and childhood cancer. One position is required to pursue a project addressing the mechanism of nonsense-mediated decay (NMD), one of the cell’s key mRNA quality control pathways to limit the synthesis of faulty proteins. The other position will also be integrated into the SFB 1036 “Cellular Surveillance and Damage Response” addressing mechanisms of stress induced regulation of mRNA 3’ end processing.

The successful candidates (m/f) will be highly motivated and interactive scientists to join an international and collaborative team. You hold a degree in molecular biology, genetics, or biochemistry and ideally have a background in molecular and RNA biology. Experience in systems approaches such as ribosomal profiling and/or proteome-, mRNP-, or transcriptome analysis on a global level including bioinformatic skills will be an advantage.

The positions are available for three years with potential extension.

Please apply to:

Andreas Kulozik, MD, PhD

with a letter summarizing previous work experience and contact information of two referees.


We stand for equal opportunities for women and men. Severely handicapped with the same eligibility will be given priority.

GRK 1591-Posttranscriptional Control of Gene Expression: Mechanisms and Role in Pathogenesis

The Martin Luther University Halle-Wittenberg operates the research training group “GRK 1591-Posttranscriptional control of gene expression: mechanisms and role in pathogenesis” funded by the German Research Foundation (DFG).

For the working group of Prof. Großmann und Dr. Schreier the RTG is seeking a
PhD Student

MicroRNAs (miRNA) are small non-coding RNAs that influence cell physiology in health and disease. In the last years we investigated the role of miRNAs in heart hypertrophy. During the last years non-coding RNAs, have been shown to affect electrical properties of cardiomyocytes. The aim of our project is to analyze the impact of miR-221/222 and mirR-208b on electrical remodeling during heart hypertrophy and to identifie the underlying the molecular mechanisms of this influence.

We are an enthusiastic team and offer intensive training and mentoring. The successful candidate will have the opportunity to learn a wide spectrum of genetic, molecular biology, biochemical and cell biology techniques. She/he will be exposed to cutting-edge methods to study translational aspects of cardiovascular pathology (e.g. genetic knockout models, next-generation sequencing, in vivo methods, patch clamping). The willingness to participate in animal studies is mandatory. For further information can be obtained at www.medizin.uni-halle.de/index.php?id=786 or www.medizin.uni-halle.de/index.php?id=272.

Your profile:
We are looking for self-motivated individuals with a diploma or master’s degree in biochemistry, biology, veterinary medicine or related subjects. Previous exposure to and experience with basic biochemical and molecular biology techniques as well as interests in molecular aspects of cardiovascular research or RNA biology is essential.

Please send your application including a letter of motivation, CV, certificates, recommendation letters in one pdf file.
The position is limited to 3 years and the salary will be based on TV-L (65%).
The working Group of Prof. Großmann and Dr. Schreier is located at the Julius Bernstein Institute of physiology at the Martin Luther University of Halle-Wittenberg, Halle (Saale), Germany.

For further information please contact Dr. Barbara Schreier, phone 0049-3455574759 or barbara.schreier@nulluk-halle.de.

The Martin Luther University of Halle-Wittenberg is committed to increase the percentage of female scientists and encourages female applicants to apply. Among candidates of equal aptitude and qualifications, a person with disabilities will be given preference.

To apply for the position please send the application documents until the 15th of July 2016 either via e-mail to barbara.schreier@nulluk-halle.de or to the following address: Martin-Luther University Halle-Wittenberg, Julius Bernstein Institute of physiology, Magdeburger Str. 6, 06112 Halle/Saale, Germany. We ask for your understanding that we cannot return application documents that are sent to us by post. We apologize for any inconvenience this may cause.

Postdoctoral Researcher Positions at The Ohio State University

Two molecular biology Postdoctoral Researcher positions are available at The Ohio State University to work in a 20-member Nanobiotechnology and RNA nano technology  interdisciplinary lab directed by Peixuan Guo (http://rnanano.osu.edu/Guo/peixuanguo.htmlhttps://www.youtube.com/watch?v=rRGYHFulzkQhttps://www.youtube.com/watch?v=LpUGuEQos6Y). Please send CV to Nancy Wardle (wardle.5@nullosu.edu) and Dr. Hui Zhang (zhang.7173@nullosu.edu; phone number: 614-293-2188).

The Ohio State University is an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation or identity, national origin, disability status, or protected veteran status.