Employment Opportunities

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Postdoc Position on Nonsense-Mediated mRNA Decay (NMD)

The laboratory of Prof. Oliver Mühlemann at the University Bern, Switzerland (http://muehlemann.dcb.unibe.ch/) has an opening for a postdoctoral fellow starting in August 2014 or upon mutual agreement. The position is part of a newly funded Swiss national research center for RNA & Disease.

Candidates must have a Ph.D. in molecular biology or biochemistry and a sound practical and theoretical background in RNA biology.
If you…

  • are top motivated to participate in the quest for understanding the molecular underpinnings and the biological importance of NMD in human cells
  • are an independently and rigorously working and thinking scientist
  • have ample social skills, like to work in a team and help junior scientists

…then you might be the person we are looking for.

We can offer a scientifically stimulating environment, friendly co-workers, access to state of the art technology and lots of exciting research. Moreover, Bern is wonderful place to live. The position is financially secured for 3 years and salary is according the SNF guidelines.

Applications should be submitted electronically as a single PDF and contain a short statement of interest, your CV, publication list and the coordinates of three academic references. Application deadline: May 18, 2014.

Investigate Molecular Mechanisms of Neurodegenerative Diseases

An NIH-funded postdoctoral fellow position is available to investigate molecular mechanisms of neurodegenerative diseases and to design and develop RNA-based therapeutic approaches to correct molecular defects associated with disease. We utilize molecular, cellular, biochemical techniques to study disease pathways in vitro and in animal models. More information about the lab is available at http://hastingslab.com

The start date for this position is flexible but can begin immediately and can extend for up to three or more years. We are located at the Chicago Medical School at Rosalind Franklin University of Medicine and Science in North Chicago. Applicants should send their CV and contact information for references to [email protected]

Postdoctoral fellow position in small RNAs and gene regulation

We are seeking an excellent candidate for research in microRNA-mediated regulation of mRNA expression, its integration with other regulatory factors, and mechanisms of their interactions. Our lab uses transcriptome-wide as well as targeted approaches in molecular biology and biochemistry to study post-transcriptional gene control.

The successful candidate will be a highly motivated, independent Ph.D. scientist with prior experience in RNA biology. Good communication and organizational skills are a must, and familiarity with transcriptome-wide techniques and bioinformatics are a big plus.

The position is available immediately. The Karginov lab is located in the University of California, Riverside. Applicants should send a cover letter with research interests, CV, and contact information for 3 references to [email protected].

Postdoctoral Scholar position in the laboratory of Dr. Ruslan Afasizhev

Postdoctoral Scholar position is available in the laboratory of Dr. Ruslan Afasizhev at the Department of Molecular and Cell Biology, Boston University Medical Campus. Our NIH-funded program focuses on mechanisms of RNA processing in Trypanosomes. The areas of mitochondrial mRNA editing, mRNA stability and small RNA biogenesis are of particular interest. Established collaborations extend into structural biology, mass spectrometry and bioinformatics. Required qualifications include strong background in molecular biology and biochemistry, and a record of peer-reviewed publications. Experience in RNAi, NGS-based transcriptome analysis, protein purification, mass spectrometry and parasite genetics is desirable, but not required. This position carries a salary of $42,000-45,000, commensurate with experience, and is available immediately. Funding will be provided for three years although fellowship applications are encouraged. To apply, please send a letter of intent, CV and contact information for three references to [email protected]. In-person interview can be arranged at the RNA Society Meeting in Quebec City.

Research Scientist – RNA Biology

RaNA Therapeutics is an energetic, rapidly growing biotechnology company in Cambridge, MA founded by leading scientists from industry, Massachusetts General Hospital and Harvard Medical School. RaNA’s mission is to discover and develop drugs to improve health for patients by modulating disease-associated transcriptional, post-transcriptional and translation mechanisms, thereby restoring normal expression of targeted proteins.

We are currently seeking a highly motivated, creative and talented Research Scientist to join our RNA Biology group.  Reporting to the group leader, this position will be responsible for exploring post-transcriptional and translational mechanisms to regulate protein expression and function, and undertaking mechanism of action studies to support corporate goals.

Qualifications:

  • PhD in biological sciences or related field with a solid understanding and demonstrated achievements in RNA biology, post-transcriptional mechanisms and translation.
  • Strong experience with biochemistry and molecular biology techniques, next generation sequencing techniques, high-throughput and traditional RNA-RNA and RNA-protein interaction mapping techniques, RNA-ribosome interactions (e.g. ribosome profiling, etc.), RNA structure determination and modulation.
  • Demonstrated ability to troubleshoot technical assays, instruments and protocols.
  • Excellent organizational and time management skills, the ability to generate high quality data under tight deadlines
  • Ability to multitask and work independently and collaboratively as part of an interdisciplinary team in a matrix environment with 20 scientists
  • Bioinformatics and/or in-depth mass spectrometry experience are strong pluses
  • Industry experience is desired

RaNA Therapeutics is committed to equal employment opportunity. All applicants must have authorization to work for RaNA in the U.S. RaNA offers highly competitive compensation packages and benefits including health/dental insurance, retirement plan, and more.  Email contact: [email protected]

Postdoctoral position: Evolution of Translational Controls

An NSF-funded postdoctoral position is available starting as early as Summer, 2014 in the Haag Lab at the University of Maryland, College Park (UMCP). The project will examine how translational controls and RNA-binding proteins that mediate them evolve over short time scales (see Beadell et al. 2011 PNAS 108:19672 and Liu et al. 2012 Development 139:1509). The research will use the germ line of Caenorhabditis nematodes (C. elegans and its relatives) as an experimental system. The ideal candidate will have a strong background in molecular biology or biochemistry, preferably with experience characterizing mRNA translation and/or RNA-protein interactions. Prior experience with C. elegans or molecular evolution is not essential. Support is available for up to three years, but the successful applicant will apply for external fellowships as appropriate.

UMCP is a large comprehensive research university located just three miles from Washington, DC. In addition to strong research groups in genetics, evolution, and molecular biology on the campus, its proximity to the NIH, Johns Hopkins University, and other research institutions provides easy interaction with a wider community of scientists.

If interested, please email a CV, cover letter, and PDFs of up to three publications to [email protected]. Applicants will be contacted for names of references if/when appropriate.

Chair of the Department of Biology Baylor University

POSITION: Chair of the Department of Biology Baylor University

QUALIFICATIONS: The successful candidate should have an outstanding record of research accomplishment, wide national visibility, and demonstrated leadership experience. The Chair must be committed to excellence in teaching, including support of innovative learning paradigms. The Department seeks candidates who use cellular and molecular approaches to investigate basic biological questions with application in the health sciences. The Chair will have an exemplary record of scholarly achievement, a vibrant record in externally funded research (including NIH support), and outstanding leadership qualities and administrative abilities. It is expected that candidates for this position will have an earned doctorate in the biological sciences and experience sufficient to merit appointment with tenure at the rank of Full Professor. The Chair will work with the faculty toward a vision for the future of the Department and toward further advancement of its program through a continuing commitment to excellence in discovery and learning.

RESPONSIBILITIES: Baylor Biology is building a world-class faculty with emphasis on innovative research as a path to discovery of new knowledge. The chair will advance the department’s prominence in research and education at the graduate and undergraduate levels. The chair will lead an expansion in the department’s research in cell and molecular biology with novel applications in the health sciences. The chair will provide active leadership that sustains the diverse group of current faculty investigating fundamental biological science in its many aspects, including ecology and organismal biology. The Chair should have a clear, strategic vision for further advancing the research and education programs in the Department.

RANK AND SALARY: Commensurate with qualifications and experience.

SUBMISSION DEADLINE: Applications will be accepted until the position is filled.

APPLICATION PROCEDURE: Please submit a letter of application, current curriculum vitae, and transcripts. Include names, addresses, and phone numbers of three individuals from whom you have requested letters of recommendation to:

http://www.baylor.edu/hr/index.php?id=81287

Post-doctoral fellow in the Biochemistry and Chemical Biology of Spliceosome Regulation

The Genome Sciences Centre within the British Columbia Cancer Agency in Vancouver, British Columbia, Canada has an immediate opening for a post-doctoral fellow in the laboratory of Dr. Gregg Morin, to study the mechanisms-of-action of pharmacological inhibition of proteins that regulate pre-mRNA splicing. The scientist will join a collaboration with Drs. Samuel Aparicio and Sohrab Shah that is using global genomic and proteomic technologies to identify changes in alternative splicing due to inhibition of several classes of enzymes that regulate spliceosome function. The objective is to investigate how these enzymes regulate genome-wide spliceosomal function and splice site choice.

The position will perform laboratory research to design and interpret experiments using biochemical, proteomic, molecular and genomic tools to investigate the functional mechanisms of enzyme inhibition on the spliceosome and its regulatory proteins in human cancer cells. The team has access to exceptional tools for next generation sequencing, bioinformatics, and advanced proteomics. The candidate should have experience in ribonucleoprotein biochemistry, mammalian tissue culture, enzymatic assays, recombinant protein purification, molecular biology, RNAi, and a comprehensive understanding of splicing and spliceosome function.

All qualified candidates are encouraged to apply; however, Canadian citizens and permanent residents will be given priority.

Additional information can be obtained at www.bcgsc.ca.

Applicants should send a cover letter, curriculum vitae, and names of three referees by email to: Dr. Gregg B. Morin ([email protected])

Duration: 1 year renewable

Postdoctoral scholar positions

Postdoctoral scholar positions are available at the Nanobiotechnology Center of the University of Kentucky and the NCI Cancer Nanotechnology Platform Partnerships (CNPP) program directed by Dr. Peixuan Guo (http://nanobio.uky.edu/Guo/peixuanguo.html). Strong background in one of the areas of Molecular Biology, Biochemistry, Genetics, Cell Biology or RNA Chemistry is preferred. To apply, please contact Dr. Hui Zhang at email: [email protected]. The University of Kentucky is an Equal Opportunity and Affirmative Action Employer.

Seeking a motivated postdoc

Seeking a motivated postdoc to investigate novel mechanisms of cap-independent translation via translation enhancing sequences located in the 3′ UTRs of plant viral RNAs.

Desired expertise: RNA-protein interactions, structural biology, computational modeling, good writing skills, ability to work independently and also be a team player in a collaborative lab environment. Experience in plants and/or viruses and/or translation is an advantage but not necessary. However, interest in working with, and learning about, all three is a must.

Can start immediately (March 2014), but we are willing to wait for the best candidate to complete Ph.D. or other commitments if necessary. Duration: 3 years depending on progress. This project is funded by a recently awarded NIH R01 grant.

Please mention this advertisement when applying for the position.

URL: http://www.plantpath.iastate.edu/millerlab/
Email: [email protected]

Postdoctoral research position is available in the laboratory of Regulation of Protein Synthesis led by Dr. Fátima Gebauer

One postdoctoral research position is available in the laboratory of Regulation of Protein Synthesis led by Dr. Fátima Gebauer. The successful candidate will investigate the role of RNA binding proteins in cancer progression using cutting edge genomics technologies and molecular and cellular biology assays. The candidate will integrate on a team with interests in post-transcriptional regulation of gene expression and molecular mechanisms of translational control.

Requirements: Candidates must hold a PhD degree on Molecular Biology, Cellular Biology, Biochemistry or Biomedicine. Expertise in RNA and protein manipulation is required. Experience in Bioinformatics, Genomics, Proteomics and Cancer Biology will be valued. Personality: highly motivated, analytical, interactive and independent.

Duration: 3 years
Starting date: As soon as 1st of April 2014
Email: [email protected]