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The Center for RNA Biology (http://www.urmc.rochester.edu/rna-biology/), directed by Lynne E. Maquat, PhD, and David H. Mathews, MD, PhD, invites applications for a tenure-track position at the ASSISTANT, ASSOCIATE or FULL PROFESSOR level. We are seeking outstanding candidates holding a PhD and/or an MD degree(s) and at least two years of post-doctoral training with research interests in any area of RNA biology. Emphasis is being placed on the study of mammalian-cell RNA-protein interactions and function, possibly using large-scale transcriptomic and proteomic approaches. Successful applicants are expected to develop independent, externally funded research programs and to contribute toward graduate- and medical-school teaching. The University of Rochester Medical Center and the adjacent College of Arts, Sciences and Engineering are part of a world-class life sciences research campus, providing excellent opportunities for interactions and collaborations, and offer an outstanding research environment with established strengths in RNA Biology. Center for RNA Biology members have expertise in post-transcriptional processing and regulation, genome stability, structural and functional characterization of molecular interactions, computational biology, biophysical chemistry and disease-associated RNA metabolism. Studies encompass rRNA, pre-mRNA, mRNA, tRNA, lncRNA, miRNA and piRNA in humans, model organisms and pathogens.
Applicants should forward a PDF file with their cover letter, CV, descriptions of research accomplishments and future research plans [and arrange for three letters of reference to be sent] to Coryn Herrema, Director, Executive and Senior Faculty Recruitment at [email protected] and also apply on line at www.rochester.edu/jobopp , job number 190621, and The University of Rochester has a strong commitment to principles of diversity and, in that spirit, actively encourages applications from groups underrepresented in higher education.
The Zheng lab studies the activity and function of post-transcriptional gene regulation in the nervous system. Current research projects investigate alternative splicing, nonsense-mediated mRNA decay and long non-coding RNA in the brain. For details please visit http://zhenglab.ucr.edu. Our lab is fully equipped with modern instruments for neurogenetics research and is housed in a newly-open research building. The position offers an amazing opportunity to continue training in neuroscience and RNA biology with an emphasis on neuronal cell and molecular biology, imaging, stem cells, mouse genetics, biochemistry, genomics, next generation sequencing and informatics approaches. Strong background in RNA biology, biochemistry, genomics, or computational biology is highly preferred. PhDs with expertise in next generation sequencing technology (CLIP-Seq and Ribo-Seq) and biochemistry are strongly encouraged to apply. Salary is commensurate upon experience and qualifications.
University of California Riverside has a vibrant research environment and is the fastest growing campus of UC. Particular strengths on the campus include neurodevelopmental disorders, glial-neuronal interactions, genetics, epigenetics, genomics, bioinformatics, integrative immunology, cancer biology, microRNAs, vector biology, bioengineering and nanotechnology, and synthetic and analytical chemistry.
Riverside, with the amazing all-year-round weather of sunny Southern California, is a wonderful place to live, providing ample cultural and entertainment opportunities in a safe and comfortable community with very affordable housing and living expenses.
Please send CV, a description of research experience and interests, representative publications, and two or three references with contact information to Dr. Sika Zheng [email protected] as a single PDF file. We are especially interested in those who are energetic and highly motivated for career advancement. Please arrange recommendation letters sent separately to [email protected]
A postdoctoral position to study the mechanisms and functional roles of localized RNAs is available immediately in Dr. Stavroula Mili’s lab at the National Cancer Institute, National Institutes of Health, Bethesda, MD. The lab is interested in understanding the regulation of RNA localization by cancer-associated proteins and the contribution of localized RNAs to tumor progression. The work relies on a variety of cell biological, microscopical and biochemical approaches in 2D and 3D cell culture systems. The research program is funded by the NIH Intramural program and is supported by state-of-the-art facilities on the NIH campus.
Interested candidates must have received a Ph.D. degree in cell biology, biochemistry or related discipline, and be highly motivated to pursue and design innovative research directions.
Applications should include a CV, brief description of research interests and prior accomplishments, contact information of at least 3 references and preferred start date. Please e-mail application materials to [email protected]
The NIH is dedicated to building a diverse community in its training and employment programs.
DHHS/NIH is an Equal Opportunity Employer.
Research Technician Position in the Lab of Dr. Davide Ruggero at the University of California, San Francisco
A Research Technician position is currently available for immediate employment in the lab of Dr. Davide Ruggero at the University of California, San Francisco in the Helen Diller Family Cancer Research Building (at the Mission Bay campus) to study the molecular mechanisms that contribute to cancer development. The employee will have the opportunity to publish their research in preeminent scientific journals such as Cell, Nature, Cancer Cell, and Molecular Cell. Previous employees holding this position have successfully obtained entrance into some of the most prestigious medical schools and graduate schools in the country.
Absolute Qualifications: Highly motivated individuals who have clearly demonstrated a passion for scientific research holding a recent B.A. or B.S. (but not M.S.) in relevant fields such as biology, biochemistry, molecular biology, genetics, etc. Applicants must have a GPA higher than 3.4 to be eligible. Previous independent laboratory experience outside of required courses is mandatory; experience in computational analysis, RNA biology and experience with handling mice is highly preferred. Applicant should be an effective communicator, be able to take the initiative to address research issues, be able to work independently, be detail-oriented and organized, and also be a team player that works well with other members of the lab. Applicant must exhibit a strong commitment to performing scientific research and desire to pursue a Ph.D. in biological sciences. A two-year commitment is highly preferred. Only applicants who can provide three professional letters of reference on their research capability from academic professionals will be considered for the position.
Preferred qualifications: Proficiency in MS Office and Adobe software including Word, Excel, Photoshop, Illustrator and PowerPoint.
Responsibilities and technical expertise: The employee will work very closely with and receive training from postdoctoral fellows, graduate students, and clinical fellows within the lab. Primary job duties include: performing experiments utilizing western blot analysis, RNA isolation, PCR, tissue culture, mouse genotyping, immunohistochemistry, and mouse dissection. Secondary duties include: laboratory organization, ordering, and ensuring safety compliance.
Resume (containing names and contact information of professional references) and cover letter should be sent to: christine.milentis (at) ucsf.edu.
Postdoctoral Position in Dr. Takahisa Nakamura’s Laboratory at Cincinnati Children’s Hospital Medical Center (CCHMC)
A postdoctoral position is available in the Dr. Takahisa Nakamura’s laboratory at Cincinnati Children’s Hospital Medical Center (CCHMC). The lab focuses on studying the mechanism of RNA modification and its impact on metabolism in the pathogenesis of metabolic diseases such as obesity and diabetes. The successful candidate will be involved in molecular/genetic approaches to reveal the significance of RNA modificaiton. This project is based on our previous studies (Cell 2010; Diabetes 2014; PNAS 2015; Cell Reports 2015).
We are looking for an individual who is highly motivated, inquisitive, well-trained in RNA biology, and positively contributes to the collaborative atmosphere of the lab.
Please email your CV, description of your interest in the lab’s research, your previous experience, and contact information of at least three references to Takahisa Nakamura ([email protected]).
CCHMC is an Equal Opportunity Employer. Qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, age, genetic information, physical or mental disability, military or veteran status, sexual orientation, or other protected status in accordance with applicable federal, state, and local laws and regulations.
Our lab is focused on understanding the molecular mechanisms underlying ALS (amyotrophic lateral sclerosis, a fatal neurodegenerative disease) pathogenesis. We are investigating the role of ALS-associated, RNA-binding proteins in response to cellular stress, particularly those stressors that are relevant to ALS. We have several investigations involving the association of these proteins with cytoplasmic stress granules. For more information, visit: www.boscolab.com. There is an open position for a project that entails RNA-handling (i.e., RNA precipitation methods followed by RNA-seq), cell culture (standard and also involving iPSCs derived from ALS patients) and proteomics using mass spectrometry. The position is available immediately and requires a 2-year minimum commitment.
The candidate should have a PhD in the biological sciences. Applicants with experience using RNA-based techniques are encouraged to apply. Prior experience in the ALS field is not a prerequisite, although applicants should have an interest in neurodegenerative disease and/or biomedical research.
Postdoctoral position at Institut Curie (Paris area, France) – Alternative polyadenylation in anticancer drug resistance.
Polyadenylation, Splicing, Cancer, Chemotherapy, DNA damage, RNA-seq, CLIP-seq.
We are seeking a highly motivated postdoc to study the role of alternative polyadenylation in the context of cancer cell resistance to genotoxic anticancer agents. The project will involve the use of genome-wide approaches (RNA-seq and CLIP-seq) to analyse specific RNA-binding proteins involved in this process. The project is based on our previous studies (Dutertre et al., Nat Struct Mol Biol 2010; Decorsière et al., Genes Dev 2011; Dutertre et al., Nat Commun 2014; Dutertre et al., TIBS 2014).
Lab and institute:
The team (“RNA biology linked to DNA damage”, head Stephan VAGNER) includes 2 researchers, 3 engineers, 3 postdocs and 2 PhD students (5 nationalities). The general interest of the team is in RNA regulations in the contexts of DNA damage response and cancer. The lab is located in the Paris area (France) and is part of Institut Curie, an internationally renowned foundation devoted to cancer care and clinical, transfer and basic research (from physics to biology). The research institute has various technology platforms (genomics/ NGS, proteomics, bioinformatics, imaging, cell screening, in vivo and preclinical investigation, chemical library, tumor collections, etc.). With more than 80 nationalities at Institut Curie, English is the commonly used language in the lab and in the institute.
The candidate must hold a PhD and be the first author of at least one accepted publication. Skills in molecular biology are required; skills in RNA biology are strongly desired.
Start date: January 2016.
Duration: 36 months.
3-year salary is available but the selected candidate will be encouraged to apply for a postdoctoral fellowship.
Project supervisor: Martin DUTERTRE (PhD, permanent researcher)
Send CV, motivation letter and 2 letters of support to [email protected]
A postdoctoral position is available in the laboratory of Dr. Julia Salzman at Stanford University. The lab focuses on studying the mechanism of biogenesis and decay of circular RNA and their function. The successful candidate will be involved in either molecular/genetic or statistical/bioinformatics approaches to answer the above questions.
We are looking for an engaged, inquisitive and highly motivated individual who will make a positive contribution to the collaborative atmosphere of the lab. See med.stanford.edu/salzmanlab.html for more details about the lab.
Please contact Julia Salzman ([email protected]) with your curriculum vitae and description of your interest in the lab’s research as well as previous experience. In addition, please submit three letters of recommendation.
Postdoctoral and graduate studentship positions in RNA synthetic biology at the Alberta RNA Research and Training Institute (ARRTI)
The newly-established research group of Dr. Nehal Thakor is currently accepting applications for a postdoctoral fellow and graduate studentship positions in the research area of RNA synthetic biology. Applicants will ideally have experience in SELEX, RNA chemical probing, and RNA structure function analysis. Experience with RNA-seq and RNA bioinformatics will be an asset. The postdoctoral position is tenable for a period of one year, and may be extended depending on funding and performance.
Dr. Thakor is a Campus Alberta Innovates Program research chair in Synthetic Biology and RNA-based system. The Thakor lab (http://www.uleth.ca/artsci/biochemistry/thakor-group) is focused on RNA synthetic biology and protein translation regulation.
Interested applicants are encouraged to apply by contacting Dr. Nehal Thakor at [email protected].
Positions will remain open until filled.
A NIH-funded postdoctoral position for a highly self-motivated scientist is available in the ZZ lab at Carnegie Institution of Science, Department of Embryology. Research in our lab focuses on the impact of transposons during animal development, disease, and aging processes. We build tools to quantify the transposon activities and uncover the mechanisms that control transposons. The candidate will join a young and highly energetic family. Current research directions in our lab include:
1. Studying piRNA biogenesis and transposon silencing in animal (mouse and fly) germline.
2. Building transposition reporter system to probe transposition events.
3. Uncovering transposon control mechanisms in somatic cells.
4. Establishing genome-wide sequencing method to quantify DNA breaks.
Job requirements: Applicants should be creative individuals who are willing to ask big questions and challenge established dogmas.
I am seeking a qualified and motivated candidate to study the role of DEAD-box proteins in messenger RNA regulation in E. coli. The focus of the lab is on prokaryotic RNA metabolism, with particular emphasis on the cellular roles of DEAD-box proteins and ribonucleases. Candidates with a recent Ph.D. degree and a background studying any aspects of RNA metabolism in prokaryotes are welcome to apply. Applicants should send by e-mail (as a single PDF) a cover letter, CV, summary of research experience and contact information of three references.
Email: [email protected]
A postdoctoral position is available in the laboratory of Dr. Ryuya Fukunaga at Johns Hopkins University School of Medicine. The laboratory is focused on understanding the molecular mechanisms of biogenesis and function of small silencing RNAs such as miRNAs, siRNAs, and piRNAs. We are also interested in post-transcriptional RNA regulation. We employ a wide range of approaches that include biochemistry, Drosophila genetics, cell culture system, deep-sequencing, and X-ray crystallography. We are looking for a highly motivated and enthusiastic new member of the lab. Candidates must have received (or be expecting) a Ph.D. or M.D. within the past five years in molecular biology, biochemistry, genetics, cell biology, structural biology, or a related discipline. Candidates with strong background in biochemical, molecular, cellular, and genetic analyses in RNA research are encouraged to apply.
More information is available at: http://biolchem.bs.jhmi.edu/Pages/facultydetail.aspx?FID=755
Please email a cover letter, CV, a brief summary of research interests, accomplishments, and career goals, and contact information of at least three references to Dr. Ryuya Fukunaga at [email protected]
The Johns Hopkins Medical Institutions provide a stimulating and collaborative environment for biomedical research and is an Equal Opportunity Employer.
Postdoctoral position to study the structure and function of catalytic ribonucleoproteins, Penn State University
A postdoctoral position is available in the laboratory of Dr. Andrey Krasilnikov at Penn State University. The succesful candidate will be involved in NIH-funded study of the structure and function of catalytic RNPs with the focus on the enzymes of the RNase P/MRP family. Research involves a broad spectrum of approaches ranging from biochemistry and molecular biology to X-ray crystallography.
We are looking for a highly motivated and enthusiastic new member of the lab. Considerable experience in protein purification and/or RNA work is highly desirable; experience in X-ray crystallography is a plus, but not required (the succesful applicant will have a chance to learn it if desired). Please submit your letter of intent, a short description of previous interests and achievements, your curriculum vitae, and contact information for three references to Andrey Krasilnikov ([email protected]).
New position for NCI Laboratory Chief, similar to Department Chair. The Chief will have stable funding, renovated lab space and resources to hire two new faculty, each with their own space and funding. The Chief will also have the opportunity to incorporate existing CCR/NCI PIs into the new Laboratory/Department.
Contact: [email protected]
Highly motivated postdoctoral candidates are invited to lead several new projects to address fundamental questions in Nucleic Acid Biology. Current directions in the lab include novel functions of DNA/RNA of unconventional structures, microRNA processing, and general RNA and protein homeostasis. Candidates with a strong background in biochemical, molecular, and cellular analyses of nucleic acids are encouraged to apply.
The Johns Hopkins Medical Institutions provide a stimulating and collaborative environment for biomedical research. Our lab is affiliated with the Department of Biochemistry and Molecular Biology of the Bloomberg School of Public Health and the Department of Neuroscience of the School of Medicine. The Baltimore/Washington D.C. area also offers rich professional and living opportunities.
Candidates should have a doctoral degree and strong research background. Please send a statement of research experience and career goals, a copy of Curriculum Vitae, and contact information of at least one reference to Dr. Jiou Wang at [email protected].
More information available at: http://www.jhsph.edu/faculty/directory/profile/5049/Wang/Jiou. The Johns Hopkins University is an Equal Opportunity Employer.