Employment Opportunities

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Postdoctoral Researcher Positions on Small RNA Biology in Cancer and Asthma

Postdoctoral researcher positions are available in the lab of Dr. Yohei Kirino at Computational Medicine Center (CMC)/Department of Biochemistry and Molecular Biology in Thomas Jefferson University (TJU). The lab uses originally-developed RNA sequencing/quantification tools (e.g., cP-RNA-seq: Nat Protoc 2016; Dumbbell-PCR: NAR 2015; FL-PCR: RNA Biol 2015), as well as biochemistry and molecular/cell biology, to investigate the biogenesis and function of small RNAs (e.g., hormone-dependent tRNA-derived RNAs: PNAS 2015) in the pathogenesis of cancer and asthma. For more information about the Kirino lab, please see the websites at http://www.jefferson.edu/university/research/researcher/researcher-faculty/kirino-laboratory.html and https://cm.jefferson.edu/staff-members/yohei-kirino/.

Energetic, inquisitive, and highly-motivated individuals with strong background in RNA biology and molecular/cell biology are encouraged to apply. Experience on bioinformatics analysis will be an advantage but not essential. Applicants should have a Ph. D. degree, a productive track record, and a high writing and communication skills. The successful applicant will have a unique opportunity to work in close collaboration within CMC (https://cm.jefferson.edu/) and with other research groups in TJU and UPENN.

Applicants should send 1) a cover letter with a description of past research experience, 2) CV, 3) a statement of research interests and career goals, and 4) contact information of 3 references to Dr. Yohei Kirino at Yohei.Kirino@nulljefferson.edu.

3 YEARS POSTDOCTORAL POSITION IN TRANSLATIONAL CONTROL RESEARCH

Laboratory of Dr. Juana Díez, University Pompeu Fabra, PRBB, Barcelona

RNA viruses are a major threat to human health. They also provide a fascinating window into cell biology since they interact intimately with the infected cell. Aims of the project are to decipher how emerging mosquito-borne viruses such as Zika virus efficiently translate their genomes in both mosquito and human translation machineries and how they modify the host gene expression program to their benefit.

THE INSTITUTE
Our group is integrated into the Biomedical Research Park of Barcelona (PRBB), one of the largest hubs of biomedical research in Europe. For more information please visit the web sites: http://www.prbb.org; http://www.upf.edu/virologyunit/

CANDIDATE REQUIREMENTS
– PhD in a relevant field (Translational control, RNA biology) with at least one publication in a reputable international journal.
-Fluency in spoken and written English.

The candidate should be highly motivated, self-driven and passionate about science. He/she is expected to set up work standards in research quality and reproducibility, to tutor PhD students, to be involved in grant writing and to be a team player.

CONDITIONS
3-year contract (estimated annual gross according to Spanish standards, 30.000€).
Starting date: April 2017 (or by agreement).

HOW TO APPLY
To apply please submit the following to juana.diez@nullupf.edu indicating in subject “postdoctoral position”:
1- A letter of interest that includes your laboratory experience, long-term career goals and data of availability to begin.
2- CV including the contact details of 3 referees.

Postdoctoral Position to Study Single Molecule Events in RNA Biology

The Stasevich lab at Colorado State University, in conjunction with the Parker lab at Univ of Colorado, Boulder, has one opening for a postdoctoral scientist to study single molecule events in RNA biology. This broadly defined research project would be jointly mentored by Dr. Roy Parker, a world-renowned expert in RNA biology at the neighboring BioFrontiers Institute at CU Boulder. The goal is to elucidate the dynamics of RNA in living cells, which could include transcription, splicing, translation, response to environmental cues and/or stress, and degradation. Work in this project would expand upon and apply some of the truly unique imaging technologies our lab has recently developed to monitor single mRNA translation events and protein post-translational modifications in vivo:
http://phys.org/news/2016-05-longer-lost-biochemists-gene-real.html

Ideal candidates will have a background in biophysics or RNA biology and the ability to communicate with biological scientists in other disciplines. The postdoc who fills this position will be offered a competitive salary with benefits. They will also have the unique opportunity to interact closely with multiple research groups spanning the CSU and CU systems. As the research topic is broadly-defined, the specific research direction will be somewhat flexible and dependent upon the interests and previous experience of the post-doc, meaning there is lots of room for creativity!
For more information about the Stasevich lab, please see our website at
http://sites.bmb.colostate.edu/stasevichlab/

To apply please send a C.V., cover letter, and contact information for three professional references to Tim Stasevich at tim.stasevich@nullcolostate.edu and Roy Parker at roy.parker@nullcolorado.edu.

Post Doctoral Researcher for a 3-Year Project to Work on RNA Modifications in Plants

The Department of Biology, University of Copenhagen, is recruiting a post doctoral researcher for a 3-year project to work on RNA modifications in plants. The project is jointly supervised by Associate Professors Jeppe Vinther and Peter Brodersen. The starting date is January 1st 2017 or as soon as possible thereafter. The groups are housed in Copenhagen Biocenter in central Copenhagen, Denmark (http://www.biocenter.ku.dk/).

The project aims to characterize epitranscriptomic changes during stress responses in the plant Arabidopsis thaliana by applying recently developed, in-house methodologies for detection of chemically modified nucleotides in RNA by next-generation sequencing (NGS). Some effort will also be devoted to further development of NGS-based methods to characterize RNA modifications.

We are looking for highly motivated individuals with a PhD degree in biochemistry or molecular biology. Candidates with some knowledge of bioinformatic analysis of next-generation sequencing data will be preferred, and experience in RNA biology/biochemistry is a clear advantage. Prior experience with plant molecular biology is not a formal requirement for this position.

Applicants must document their successful PhD studies by at least one first-author publication in a respectable international journal. If a manuscript is in review or in revision in a major journal, the applicant may also describe the work, and, if possible, enclose a copy of the submitted manuscript as well as documentation for its editorial handling at the journal. The position is open to all applicants regardless of nationality, and will be funded by a grant from the Novo Nordisk Foundation.

For further information on the project, please contact Peter Brodersen, e-mail pbrodersen@nullbio.ku.dk or Jeppe Vinther jvinther@nullbio.ku.dk.
Applications have to be submitted via the University of Copenhagen jobportal: ow.ly/6jTE305aCRm

Postdoctoral Research Associate to Work in the Area of Computational Biology

The Penalva lab in partnership with Smith lab at USC has an open position for a postdoctoral research associate to work in the area of Computational Biology. Successful candidates will design new algorithms and statistical methods for analyzing large-scale data sets, with the aim of answering specific biological questions concerning post-transcriptional gene regulation. The data analysis will involve massive datasets produced specifically for our projects and hold much promise for discovery. This position will require creativity in designing novel methods to meet the unique analytical challenges presented by emerging experimental technologies.

Requirements

  • PhD in Computer Science, Computational Biology, Bioinformatics, Statistics, Applied Math or Physics
  • Deep interest in solving biological problems
  • Solid programming skills and experience with C or C++
  • Ability to work comfortably in a Unix/Linux environment

This position will be particularly suitable to candidates interested in

  • Working with newly produced genomic and RNA-based sequencing data, including CLIP-seq and Ribo-seq
  • Interacting directly with experimental scientists producing data using cutting-edge technologies
  • Having opportunities to contribute to experimental design decisions
  • Gaining experience working with massive datasets from the latest sequencing technologies

Good knowledge in RNA biology is a plus.

Interested applicants should send a CV (including a list of publications), a statement of research interests and contact information for 3 references to Dr. Andrew D. Smith at: andrewds@nullusc.edu or Luiz O Penalva penalva@nulluthscsa.edu

The position is avaliable immediatelly and is for a minimum of 3 years.

Postdoctoral Position in Prokaryotic RNA Biology

I am seeking a qualified and motivated candidate to study the role of DEAD-box proteins in messenger RNA regulation in E. coli. The focus of the lab is on prokaryotic RNA metabolism, with particular emphasis on the cellular roles of DEAD-box proteins and ribonucleases. Candidates with a recent Ph.D. degree and a background studying any aspects of RNA metabolism in prokaryotes are welcome to apply. Experience with analyzing genome sequencing data is desirable. Applicants should send by e-mail (as a single PDF) a cover letter, CV, summary of research experience and contact information of three references to cjain@nullmiami.edu.

Post Doctoral Researchers to Pursue Specialized Research Training

The Miles lab at the OSUCCC is looking for Post Doctoral researchers to pursue specialized research training and experience under the guidance of a Dr. Wayne Miles. Our resesearch focuses on understanding how different oncogenic stimuli change the transcriptional, post-transcriptional and proteomic landscape of normal and cancer cells. We are searching for post-doctoral researchers to develop, adopt and implement new laboratory methods to achieve achieve these goals. Very high technical standard required in tissue culture manipulation of cells (shRNA, siRNA, CRISPR and transfections), RNA-protein interaction technologies (RNA-IPs, Ribosome capture, PAR-CLIP and polysome gradients) and global profiling (RT-PCR, RNA-seq and proteomics). Bioinformatics skills would be an advantage. Participates in analyzing data for reports for the purpose of grants submissions; trains staff in molecular biology techniques. Post-Doctoral Researcher will  attend and present at national and international conferences as well OSUCCC meetings. Very high standard of written and spoken English required.

https://wexnermedical.osu.edu/careers/research/422045

Multiple Postdoctoral Fellow Positions in RNA Genomics and Bioinformatics

Multiple postdoctoral fellow positions in RNA genomics and bioinformatics are available in Dr. Yi Xing’s lab (http://www.mimg.ucla.edu/faculty/xing/) at UCLA. The central interest of our lab is to elucidate the variation, regulation, and function of alternative RNA processing and modification in mammalian cells. We develop computational and statistical methods for analyzing transcriptome complexity and alternative mRNA isoform expression using high-throughput technologies (PNAS 2014; Genome Biology 2013; Nature Communications 2016; Nature Methods 2016). We also use computational and genomic methods to elucidate RNA regulatory networks in health and disease (Cell Stem Cell 2014; Molecular Cell 2014; Neuron 2014; Elife 2015; Genome Biology 2016; Cell Reports 2016).

  1. Postdoctoral Fellow in RNA Bioinformatics: We are looking for a computational biology postdoctoral fellow to conduct cutting-edge research in the fields of transcriptome bioinformatics and RNA systems biology. The postdoctoral fellow will develop computational and statistical methods to elucidate the variation and dynamics of RNA regulatory networks using big data and systems biology approaches, and apply these methods to large-scale genomic and transcriptomic datasets including massive clinical RNA-seq data. We are looking for enthusiastic and career-oriented applicants with strong experience and publication record in statistical genomics, computational biology, RNA bioinformatics, or related fields.
  1. Postdoctoral Fellow in RNA Genomics: We are looking for a postdoctoral fellow to develop novel genomic tools for studying alternative splicing or RNA modifications (e.g. m6A RNA methylation), and apply these tools to elucidate alternative mRNA and protein isoform complexity in cancer and neurodegenerative diseases. The applicants should have a Ph.D. in molecular biology, biochemistry, genetics, or related fields with experience in RNA biology.

The successful candidate will work in a hybrid computational and experimental environment and interact with world-class collaborators in the fields of RNA biology, genomics, computational biology, and biomedical sciences. Interested candidates should send a CV and names of three referees to Dr. Yi Xing, Professor, Department of Microbiology, Immunology, and Molecular Genetics (MIMG), UCLA, at yxing@nullucla.edu.

Assistant Professor, Molecular Biology

UNIVERSITY OF CALIFORNIA, SANTA CRUZ
DEPARTMENT OF MOLECULAR, CELL & DEVELOPMENTAL BIOLOGY
Assistant Professor, Molecular Biology

The Molecular, Cell & Developmental Biology Department at the University of California Santa Cruz (UCSC) invites applications for 1-2 tenure-track positions at the Assistant Professor level in Molecular Biology. Applicants should be addressing fundamental questions in molecular biology using state-of-the-art experimental approaches and have an outstanding record of research accomplishments. We particularly encourage applicants who complement the department’s existing strengths in studying RNA, chromatin, cell division, macromolecular structure, and neuroscience and use quantitative methods. Candidates will be expected to establish a vigorous externally funded research program, contribute to the intellectual vitality of the UCSC scientific community, teach at the undergraduate and graduate levels in the classroom and through mentorship, and provide service to the campus and their profession. The successful candidate will be able to work with students, faculty, and staff from a range of social and cultural backgrounds, and we especially welcome applicants who will contribute to the diversity and excellence of the UCSC academic community through research, teaching, and/or service.

RANK: Assistant Professor

SALARY: Commensurate with qualifications and experience, academic year (9-month) basis

BASIC QUALIFICATIONS: A Ph.D., M.D. or equivalent foreign degree in biology or a related field and postdoctoral research experience.

POSITION AVAILABLE: July 1, 2017, with academic year beginning September 2017.

TO APPLY: Applications are accepted via the UCSC Academic Recruit online system and must include: 1) Cover letter; 2) Curriculum vitae including a list of published manuscripts and pre-prints (no “in preparation”); 3) Introductory statement describing: a. your most significant scientific accomplishments as a graduate student, b. your most significant scientific accomplishments as a postdoc, c. your overall goals and vision for a research program at UCSC, and d. the experience and qualifications that make you particularly well-suited to achieve those goals (750 words max); 4) Research statement (1500 words max; figures encouraged); 5) Teaching statement (500 words max); and 6) Three letters of reference.* Applicants are invited to submit an optional statement addressing their past and/or potential contributions to diversity through research, teaching, and/or service. Documents/materials must be submitted as PDF files.

Apply at https://recruit.ucsc.edu/apply/JPF00393

Refer to Position #JPF00393-17 in all correspondence.

*All letters will be treated as confidential per University of California policy and California state law. For any reference letter provided via a third party (i.e., dossier service, career center), direct the author to UCSC’s confidentiality statement at http://apo.ucsc.edu/confstm.htm

CLOSING DATE: Review of applications will begin on November 23, 2016. To ensure full consideration, applications should be complete and letters of recommendation received by this date. The position will remain open until filled, but not later than 6/30/2018.

UC Santa Cruz faculty make significant contributions to the body of research that has earned the University of California the ranking as the foremost public higher education institution in the world. In the process, our faculty demonstrate that cutting-edge research, excellent teaching and outstanding service are mutually supportive.

The University of California is an Equal Opportunity/Affirmative Action Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, age, or protected veteran status. UC Santa Cruz is committed to excellence through diversity and strives to establish a climate that welcomes, celebrates, and promotes respect for the contributions of all students and employees. Inquiries regarding the University’s equal employment opportunity policies may be directed to: Office for Diversity, Equity, and Inclusion at the University of California, Santa Cruz, CA 95064; (831) 459-2686.

Under Federal law, the University of California may employ only individuals who are legally able to work in the United States as established by providing documents as specified in the Immigration Reform and Control Act of 1986. Certain UCSC positions funded by federal contracts or sub-contracts require the selected candidate to pass an E-Verify check. More information is available here or from the Academic Personnel Office (APO) at (831) 459-4300.

UCSC is a smoke & tobacco-free campus.

If you need accommodation due to a disability, please contact the Academic Personnel Office at apo@nullucsc.edu (831) 459-4300.

THE APO WEB SITE AT: http://apo.ucsc.edu                          9/23/16

NSF-Funded Postdoctoral Position

The Chakrabarti Lab (http://www.chem.cmu.edu/groups/Chakrabarti) at Carnegie Mellon, Dept. of Chemistry, Center for Nucleic Acids Science & technology (CNAST) is seeking to hire a Postdoctoral Researcher to join an exciting NSF funded project to study Telomerase RNA structure-function in deep branching eukaryotes. Chakrabarti group uses interdisciplinary approaches involving experimental and computational tools to study RNA based enzymatic processes in human diseases. The successful candidate will be driven, creative and team-oriented. We are seeking individuals with a background in Biochemistry and/or Structural Molecular Biology. Hands on-experiences with RNA research-related methods, especially RNA-SHAPE analysis, would be a significant plus. This position is currently for one year with the possibility to extend for longer period based on performance and available funding. We welcome applicants from recent PhDs and individuals seeking additional postdoctoral training. Successful candidates will likely start November 1, 2016. Please send a cover letter, CV with publication list and names to 3 references to :kausik@nullcmu.edu

Establish an Independent Research Group, as an Externally Funded Research Fellow

We invite Expressions of Interest from early and mid career researchers who wish to be sponsored for establishing an independent research group, as an externally funded research fellow. Successful candidates will have an outstanding track record in an area that is complementary to the Department’s research interests and fits within its five broad research themes: Cell Biology, Development and Genetics; Chromosomal and RNA Biology; Infection and Disease Processes; Microbiology and Systems Biology; Structural Biology and Molecular Biophysics.
We offer a dynamic and multidisciplinary research environment with state-of-the-art facilities and access to excellent infrastructure and expertise in the wider Oxford area. Fellows benefit from a comprehensive mentoring programme and career support, and have the opportunity to recruit outstanding undergraduates and postgraduates.
Shortlisted candidates will present a seminar, attend an interview, and meet members of the department with common scientific interests. Successful candidates will be provided with support from the Departmental Research Facilitator and appropriate group leaders to assist them in their fellowship application.

The Department of Biochemistry is committed to equality and valuing diversity. Applications are particularly welcome from women and ethnic minorities.

Expression of Interest should include:
• Brief CV, including a list of your publications
• Outline of your intended research programme (up to two pages)
• Details of how your research fits within the research themes of the Department and why you would like to work in the Department
• Proposed scheme for which you are eligible
• Brief outline of the budgets required for your proposed programme
• Brief description of any unusual requirements for laboratory space and facilities
• Confidential supporting statements from at least two referees who know your research well, to be sent separately
For full guidelines please visit
www.bioch.ox.ac.uk/recruitfellows/guidelines.pdf
Closing deadline: 7th October 2016
Shortlisting decision: 21st October 2016
Interview dates: 22nd – 23rd November 2016
Informal enquiries to recruitfellows@nullbioch.ox.ac.uk

Postdoctoral Researcher Position Available Immediately in the Laboratory of Dr. Mingyi Xie

Postdoctoral Researcher position available immediately in the Laboratory of Dr. Mingyi Xie (Assistant Professor, Department of Biochemistry and Molecular Biology,

Cancer Center, School of Medicine, University of Florida) to study the Function and biogenesis of alternatively-processed microRNAs and Integrator complex-mediated RNA processing and gene regulation. The duration of this position will be 5 years, while the contract will be renewed on a yearly basis.

Applicants should submit the following to mingyi.xie@nullufl.edu:
1)      Cover letter stating: laboratory experience in RNA/protein biochemistry and bioinformatics; your long-term career goals; date of availability to begin postdoc research/technician
2)      Curriculum vitae (including publications and awards/honors)
3)      List of at least three references

Dr. Mingyi Xie was trained in the laboratory of Dr. Joan Steitz at Yale University (2010-2016), where he documented two surprising microRNA (miRNA) biogenesis pathways:

  • Herpesvirus saimiri (HVS)-miRNAs are processed by the host Integrator complex, a 14-subunit complex best known for executing the 3′-end cleavage of cellular small nuclear RNAs (snRNAs) (Cazalla, Xie and Steitz-Molecular Cell-2011; Xie et al.,-Genes & Development-2015).
  • Mammalian m7G-capped precursor miRNAs are generated from RNA polymerase (Pol) II transcription initiation sites. Whereas the nuclear-cytoplasmic export of capped pre-miRNAs is mediated by Exportin-1 (Xie et al.,-Cell-2013; Xie and Steitz-RNA Biology-2014).

The Xie lab’s immediate research goal is to further delineate the unique modes of miRNA production, including Integrator-mediated RNA metabolism, and understand the functions of these special miRNAs in herpesviruses and their hosts. Such research will allow the design of therapies for related oncogenic herpesviruses and cancers.

University of Florida (UF) is a vibrant intellectual community with many cross-disciplinery interactions. UF is ranked as top-50 world university and top-15 public university in the United States by USNEWS. Gainesville is a delightful and family-friendly city that is 1.5 hours away from major cities like Orlando, Jacksonville and Tampa Bay.

Visit http://biochem.med.ufl.edu/research/faculty/primary-faculty/mingyi-xi-ph-d/ and http://xielabuf.tk for more information

The Meyer lab in the Department of Biochemistry at Duke University

The Meyer lab in the Department of Biochemistry at Duke University is currently seeking highly motivated postdoctoral associates who are interested in RNA biology. Studies in the lab are focused on the new and exciting area of RNA epigenetics, with several projects geared toward understanding the role of RNA methylation in nervous system function. Individuals with experience in RNA biology, biochemistry, genetics, or neurobiology are especially encouraged to apply.

Requirements:
– PhD in a relevant field (such as biology, biochemistry, neurobiology, or genetics).
– Excellent communication skills and an ability to work well with others.
– Demonstration of past research productivity (publications and/or patents).

How to apply:

Send a cover letter, your CV, and the names/contact information of three references to Dr. Kate Meyer (kate.meyer@nullduke.edu).

For more information on our lab, visit www.themeyerlab.com.

Two NIH Postdoctoral Positions Available Immediately

Two NIH postdoctoral positions are available immediately in the Mangone Lab at the Virginia G. Piper Center for Personalized Diagnostics in the Biodesign Institute at the Arizona State University in the Tempe. The Mangone lab is interested in the functional genomics and genetics of post-transcriptional gene regulation using C. elegans as model system. The research plan centers on two aims:

1. To study tissue-specific 3’UTR isoforms and understand their processing mechanism in the context of alternative polyadenylation.

2. To investigate miRNA target recognition in vivo.

Applicants must have a Ph.D. in biology or related field. Expertise in molecular biology and biochemistry and in C. elegans biology is required. Experience in handling high-throughput experiments is desirable.

Contact: mangone@nullasu.edu

Postdoctoral Research Position in Single Molecule Fluorescence Microscopy of RNA

Immediately available for at least a year is a postdoctoral research position in single molecule fluorescence microscopy of RNA in the group of Professor Nils G. Walter at the University of Michigan, Ann Arbor, USA.  The project involves highly interdisciplinary, National Institutes of Health and National Science Foundation funded work targeted at the real-time fluorescence imaging of riboswitches and DNA nanotech devices.  Highly motivated and enthusiastic candidates are sought with experience in RNA biochemistry, fluorescence and/or other spectroscopies, and the enthusiasm to learn state-of-the-art biophysical techniques.  Those with the appropriate background should review the group’s web page at: http://sites.lsa.umich.edu/walter-lab and send their Curriculum Vitae and the names and addresses of three references to Dr. Nils G. Walter, Professor of Chemistry and Biophysics, via email: nwalter@nullumich.edu.  Please note that the University of Michigan is a world-class research university situated in one of the most livable cities in the US.

ASSISTANT/ASSOCIATE PROFESSOR-BIOCHEMISTRY & MOLECULAR BIOLOGY

We seek faculty candidates for a tenure-track position at the Assistant or Associate Professor level. The successful applicant will be expected to develop a well-funded research program that complements existing areas of strength in the University and the Department, including structural biology, membrane proteins, bioenergetics, genomics/genetics/epigenetics, gene expression, and cancer mechanisms. The applicant will also contribute to graduate and medical teaching. The position is state-supported with a guaranteed salary base, excellent fringe benefits, and competitive start-up funds. Further information about this position and the Department can be found at http://www.upstate.edu/biochem.

Applicants should have a Ph.D. or equivalent, postdoctoral experience, and a strong publication record. Submit a curriculum vitae and a research statement (of up to three pages) consisting of a summary of accomplishments and description of future plans, and arrange for three letters of reference to be sent to Department of Biochemistry & Molecular Biology, at biochem@nullupstate.edu.

Review of applications will begin November 1, 2016, and continue until the position is filled.