Employment Opportunities

Postdoctoral/Researh Associate position in the laboratory of Dr. Paul F. Agris within the RNA Institute (SUNY). Applicants are sought with expertise in structural biology by NMR. Successful applicant will have had experience with macromolecular structure determination by NMR (MDS), but will not need to have had experience with RNA. RNA experience is preferred. Projects include RNA/RNA, RNA/Protein and RNA/small molecule interactions involved in control of gene expression and in infectious disease.

Applicants should submit:
1) complete resume’,
2) names and contacts of three references and
3) a brief description of NMR research experience that includes those approaches/technologies with which the applicant has extensive experience.

Modern 700MHz and 500 MHz NMRs each with cryoprobes are available for data collection; HPC including GPU systems are available for data processing, structure determination, predictive interactions. The RNA Institute provides a unique research resource environment for some 50 principal investigators and ~400 researchers conducting RNA science and its applications to human health problems, technology development and drug discovery in New York’s Capital District. Albany has the cultural activities of a large city but within the environment of a small city atmosphere, ready access to the Adirondacks, Berkshires, the NY lake district, Boston, and NYC.
Submit completed application materials by email attachment to Dr. Paul F. Agris:
PAgris@albany.edu

Computational Postdoctoral Researchers in Regulatory RNAs

Two computational postdoctoral fellow positions in regulatory RNAs are available immediately in our RNA Bioinformatics lab (http://sfold.wadsworth.org).

A major ongoing research interest of our lab is functional elucidation of regulatory RNAs in gene regulation. Specific research topics can include, but not limited to, microRNAs, circular RNAs, bacterial small RNAs and lncRNAs, with applications to stem cells, cancer and other human diseases.

We are interested in two types of candidates with the following qualifications:

A: Solid understanding of statistical methods, with experience in Bayesian data analysis and modeling preferred. Experience with R is expected. Understanding of molecular biology, training in Bioinformatics and familiarity with Perl or C are pluses.

B: Solid RNA biology background. This can be from an experimental RNA lab (preferably with some bioinformatics training) to complement our existing strengths in development of novel computational methods and tools.

Contact: Ye Ding, rnarecruit@gmail.com

Postdoc position in RNA nanotechnology:

Programming RNA reaction networks within microfluidic devices Laboratory for photonics and nanostructures, CNRS, 91460 Marcoussis, France

Contact: Andre Estévez-Torres, aestevez@lpn.cnrs.fr

Starting September 2013 in the south of Paris.

The project: Living cells process information and make decisions relying on chemical reaction networks that are out of thermodynamic equilibrium. For reprogramming cell behavior, RNA is a good target candidate because i) RNA-RNA interaction can be well predicted in silico, ii) RNA turnover is fast within living cells thus efficient computing is possible, and iii) RNA production is energetically cheap in vivo.

This project asks the question whether in vitro (outside of cells) experiments provide useful information for designing efficient RNA networks in vivo. In collaboration with S. Findeiss (Vienna) for the in silico design and I. Axmann (Berlin) for the in vivo implementation, we will quantify the dynamics of RNA-based regulatory mechanisms, then of small artificial networks containing these mechanisms. We will first perform experiments with a standard microplate- reader in a cell-free transcription/translation system1, and then within highly-controlled mi- crofluidic reactors, such as our recently proposed open reactor2. Depending on the interests of the candidate, different topics within this context may be explored.

The candidate: This is a 2 year funding with an option for a 3rd year. We seek open-minded and curious candidates from a wide range of backgrounds: physics, chemistry, biology, or engineering, with interest in multidisciplinary research and with a clear taste towards experimental work. Experience with RNA and standard molecular biology is highly desired.

I am  looking for highly motivated candidates with a Ph.D. degree in the field of Molecular Biology, Biochemistry, Biology, Biomedicine or related areas.

My group studies basic gene regulation mechanisms, in particular alternative polyadenylation and RNA processing mechanisms. Work in my lab is funded by FCT (Portugal) and  the EU (FP7). The IBMC is a multidisciplinary research institution, with strong basic research, organized in three thematic units: Infection and Immunity, Molecular and Cell Biology, and Neuroscience. It harbors 37 research groups from different scientific backgrounds, 580 collaborators, 195 holding PhD and 49 post-graduate students. IBMC maintains close scientific interactions with the University of Porto, the Biomedical Engineering Institute (INEB), the Institute of Molecular Pathology and Immunology (IPATIMUP).

A postoctoral fellowship position is available to work in the group of Alexandra Moreira, Gene Regulation Group, at the IBMC,  in collaboration with Luís Ferreira-Moita, IMM, Lisbon, Portugal and Joel Neilson, BCM, Houston, USA, in the project PTDC/SAU-GMG/116621/2010, funded by FCT/MCTES (PIDDAC) and co-funded by pelo FEDER through COMPETE – Programa Operacional Factores de Competitividade (POFC).

The fellowship is due to start in May 1st, 2013, for one year, renewable for up to a maximum of two years. The application should include a letter of motivation, CV and 2 reference letters/contacts, and should be submitted on the IBMC webpage: http://www.ibmc.up.pt/gestaocandidaturas/index.php?codigo=PR102301

from the 25th March to 12th April 2013, until 5 p.m. More info at http://www.ibmc.up.pt/sites/default/files/BPD%20AMoreira%20inglês.pdf and for informal enquiries please contact: alexandra.moreira@ibmc.up.pt

A post-doctoral position is available in the laboratory of Dr. Heather Hundley in the Medical Sciences Program at Indiana University-Bloomington (http://bloomington.medicine.iu.edu/research/heather-hundley-lab/). The overall theme of the Hundley lab is to understand the biological impact of double-stranded RNA and RNA editing on post-transcriptional regulation of gene expression. We utilize a combination of biochemistry, molecular/cellular biology and genome-wide analyses (e.g. RNA-seq, RIP-Seq, CLIP-Seq) in the model organism Caenorhabditis elegans and mammalian cell culture.

Highly motivated candidates should have a PhD in Biochemistry, Molecular Biology, or related fields, excellent communication skills, and an established publication record. Experience with biochemistry, molecular biology and/or genomic techniques are preferred. Past experience working in RNA is an asset. Interested candidates should apply electronically with a CV, a statement of research interest and career goals, and the names and contact information for three references to Heather Hundley at hahundle@indiana.edu Applications will be screened until a suitable candidate is found. Indiana University is an equal opportunity/affirmative action employer.