The RNA Society's Next Meeting

RNA 2017, The Twenty-second Annual Meeting of the RNA Society

The twenty-second annual meeting of the RNA Society will be held May 30 – June 2, 2017 in Prague, Czech Republic

Organizers:
Andrea Barta, Medical University of Vienna, Vienna
Rachel Green, Johns Hopkins University, School of Medicine, Baltimore
Christopher Lima, Sloan-Kettering Institute, New York
Ron Micura, Leopold Franzens University, Innsbruck
Petr Svoboda, Institute of Molecular Genetics ASCR, Prague
Yukihide Tomari, University of Tokyo IMCB, Tokyo

Other Meetings and Conferences

RNA Nanotechnology – Discovering and Assembling RNA Architectures for Materials, Therapeutics and Diagnostics

Announcing the 2017 Gordon Research Conference on:
RNA Nanotechnology
Discovering and Assembling RNA Architectures for Materials, Therapeutics and  Diagnostics

January 22-27, 2017  Ventura Beach Marriott Ventura, CA
Chair: Neocles B. Leontis, Bowling Green State University
Vice Chairs: Tushar Patel, Mayo Clinic Thomas Hermann UC San Diego

The 2017 GRC in RNA Nanotechnology will draw on the success of the first conference on this topic, held in 2015, to foster collaborations between researchers working in the diverse fields of chemistry, biochemistry, structural biology, microbiology, cancer biology, cell biology, biophysics, pharmacology, materials, and nanotechnology, with the purpose of promoting transformative advances that will enable the diagnosis and treatment of diseases, and enable the monitoring and improvement of human health exploiting the unique properties of RNA nanostructures.

Session topics include: 

  • RNA Modeling, Folding and 3D Structure
  • Pharmacology and Immunology of RNA Nanotechnologies
  • Biology and Applications of Extracellular Vesicles
  • RNA Synthetic Biology 

Complete program and online application are available at:
www.grc.org/programs.aspx?id=16897

Keystone Symposia: Noncoding RNAs –From Disease to Targeted Therapeutics

Scientific Organizers:

Kevin V. Morris, Center for Gene Therapy, City of Hope, USA Archa Fox, University of Western Australia, Australia and
Paloma Hoban Giangrande, University of Iowa, USA

joint with the meeting on

Protein-RNA Interactions: Scale, Mechanisms, Structure and Function of Coding and Noncoding RNPs

Scientific Organizers:
Gene W. Yeo, University of California, San Diego, USA
Jernej Ule, UCL & The Francis Crick Institute, UK
Karla Neugebauer, Yale University, USA and
Melissa J. Moore, University of Massachusetts Medical School, USA

Submit an abstract and register for these Keystone Symposia conferences that will take place February 59, 2017 at Fairmont Banff Springs, Banff, Alberta, Canada.

Ribonucleic acid (RNA) binding proteins (RBPs) are rapidly being recognized as a major class of more than a thousand proteins that is widely conserved throughout eukaryotes and plays key roles in almost every aspect of RNA metabolism. RBPs interact with hundreds to thousands of coding and noncoding RNA substrates via cis-regulatory sequences or guided by associated small RNAs to form ribonucleoprotein (RNP) complexes. Increasingly, defects in the protein-RNA interactions by mutations within the regulatory proteins, RNA cis-elements or changes in protein availability or expression have led to numerous diseases. This meeting addresses critical gaps in our basic understanding of how, where and why these RNP complexes form using approaches that integrate high-throughput, massively parallel microarray, sequencing and proteomic technologies with structural biology, genomics, systems-level thinking and computational algorithms to probe RNPs at steps in the life cycle of processing both coding and noncoding RNAs. The specific aims are to: (1) Provide an opportunity and forum to gather interdisciplinary leaders in various fields to cross-fertilize a common, shared vision; (2) Introduce newcomers to the most cutting-edge methods that integrate mechanistic studies and high-throughput science; and (3) Consolidate the field moving forwards. As this unified field is relatively new, we will see shifts in current research paradigms and many opportunities should arise from interactions at this meeting.

Deadlin­es:

  • Scholarship & Discounted Abstract: October 5, 2016
  • Late-Breaking Abstract: November 2, 2016
    (for plenary short talk or workshop presentation consideration)
  • Discounted Registration: December 6, 2016

(Through this date, you can still submit an abstract via our website for poster presentation and publication in our mobile app.)

For more information and to register, please visit the meeting websites:
http://www.keystonesymposia.org/17J5 | http://www.keystonesymposia.org/17J6

Registered attendees of one meeting in a joint pair may participate in sessions of the other, pending space availability.

EMBL Course: Next Generation Sequencing: Enrichment Based Targeted Resequencing

Benes, J. Dreyer-Lamm, A. Heim

The goal of this course is to teach the fundamentals of NGS library preparation and validation using enrichment based tests like the Nextera / TruSight Rapid Capture assay. We will start with an introduction into Illumina NGS technology and the library preparation workflow. The main part will be the wet lab preparation of libraries from genomic DNA, with a focus on the critical steps and potential pitfalls of the protocol. Finally we will quality control and quantify the prepared libraries. We will also have a basic training on assay design using DesignStudio and data analysis of Enrichment based sequencing results using standard Illumina software tools like MiSeq Reporter and VariantStudio.

Audience

This course is directed towards molecular biologists, scientists and technicians who want to apply Enrichment based targeted sequencing in their lab. Knowledge of next generation sequencing technology is desirable but not essential.

http://www.embl.de/training/events/2017/ILL17-03/index.html

EMBL Course: Next Generation Sequencing: Amplicon Based Targeted Resequencing

Benes, J. Dreyer-Lamm, A. Heim

The goal of this course is to teach the fundamentals of NGS library preparation and validation using an Amplicon PCR based test like the TruSeq Amplicon assay. We will start with an introduction into Illumina NGS technology and the library preparation workflow. The main part will be the wet lab preparation of libraries from genomic DNA, with a focus on the critical steps and potential pitfalls of the protocol. Finally we will quality control and normalize the prepared libraries. We will also have a basic training on assay design using DesignStudio and data analysis of TruSeq Amplicon sequencing results using standard Illumina tools like MiSeq Reporter and VariantStudio.

Audience

This course is directed towards molecular biologists, scientists and technicians who want to apply Amplicon based targeted sequencing in their lab. Knowledge of next generation sequencing technology desirable is but not essential.

http://www.embl.de/training/events/2017/ILL17-04/index.html

8th Annual Conference: RNA Therapeutics

SMi Group announces the return of its 8th annual RNA Therapeutics conference to London on the 22nd – 23rd of February 2017. Technology in RNA interference, oligonucleotides and mRNA has revolutionised the way infectious disease, cancer and neurological disorders are treated. It is now possible to target previously ‘un-druggable’ sites, therefore expanding the range of therapeutics that selectively silence genes before the disease develops.

AstraZeneca has added another $140 million to its $1.2 billion investment into Moderna Therapeutics’ mRNA technology*. Consequently continued collaboration between pharmaceutical giants and innovative biotechnology companies, has created considerable funding and buzz around RNA research.

The main challenge in RNA therapeutics continues to be the delivery of RNA based drugs to target sites outside the liver. Join us in exploring the different delivery systems in use and in development such as transportation with nanoparticles and the ability to enhance drug stability.

We will be reviewing clinical trial updates in RNA- based therapeutics and discussing the current regulations involved in getting drug approval. Learn about the main developments currently shaping the industry and how best to tackle challenges facing RNA therapeutics.
*https://www.cambridgenetwork.co.uk/news/astrazeneca-and-moderna-therapeutics-announce-new-collaboration/

Register here: http://www.smi-online.co.uk/pharmaceuticals/uk/rna-therapeutics/booknow

Bermuda Principles – Impact on Splicing 2017

http://bermudaprinciples.org/index.html

The 2017 Bermuda Principles Impact on Splicing Conference will take place on February 28- March 3, 2017 at the Fairmont Southampton Princess Hotel in the exotic holiday island of Bermuda. We are offering an exciting conference where the venue serves as the meeting space and accommodation (http://bermudaprinciples.org/accommodation.html). This conference is acknowledging the 20th anniversary of the Bermuda Principles, a document created in Bermuda exactly 21 years ago that stated that all gene sequences would be made public in order to further scientific progress in all fields. Such data sharing has indeed advanced scientific research, including the field of splicing.

We hope to evoke a similar atmosphere by sharing our latest splicing research in this conference for the advancement of the field. We encourage young, middle and late career researchers to attend and participate, intending that this gathering will foster fruitful collaborations, inspire novel approaches to tackle existing problems and promote the great work that is going on in the field. Come and enjoy sunshine and seven exciting sessions of splicing.
http://bermudaprinciples.org/about.html

We are glad to announce that with the support of the RNA Society we are able to offer travel fellowships for early-career researchers (PhD and post-docs) for those who otherwise would not be able to attend the meeting for financial reasons.  http://bermudaprinciples.org/travelfellowships.html
If you travel in groups of 3 or more, we can provide a 10% group discount on each registration fee. Please email info@nullbermudaprinciples.org for details.

Organizers
Carika Weldon
(De Montfort University)
Ian Eperon (University of Leicester)
Cyril Dominguez (University of Leicester)
Isabelle Behm-Ansmant (CNRS-University of Lorraine)

Invited speakers
Benoit Chabot, University of Sherbrooke, Canada
Stéphane Richard, McGill University, Canada
Benjamin Blencowe, University of Toronto, Canada
Melissa Moore, University of Massachusetts Medical School, USA
Edauardo Eyras, Pompeu Fabra University of Barcelona, Spain
Jamal Tazi, Institut de Génétique Moléculaire de Montpellier, France
Jon Staley, University of Chicago, USA
Andrew Newman, MRC-LMB, University of Cambridge, UK

Sessions topics

  • RNA structure
  • Mechanisms of splicing
  • Splicing and disease
  • Link to transcription
  • Structures: big and small
  • Bioinformatics
  • Therapeutics

Deadlines
Travel fellowships: December 15, 2016 (ADT)
Abstract submission: January 5, 2017 (ADT)
Registration: January 5, 2017 (ADT)
http://bermudaprinciples.org/registration.html

Keystone Symposia: mRNA Processing and Human Disease

Scientific Organizers:
James L. Manley, Columbia University, USA
Siddhartha Mukherjee, Columbia University Medical Center, USA
Gideon Dreyfuss, HHMI/University of Pennsylvania School of Medicine

Submit an abstract and register for this Keystone Symposia conference that will take place March 58, 2017 at Sagebrush Inn & Suites, Taos, New Mexico, USA.

It has been known for decades that defects in mRNA processing can cause, or contribute to, numerous human diseases. The earliest examples of this involved simply mutations in cis-acting signal sequences (e.g., for splicing and polyadenylation) of target genes, for example the human beta globin gene in beta-thalassemia. But the number of diseases linked to defects in mRNA processing has increased dramatically in the last five to ten years, reflecting in large part insights from deep-sequencing efforts. Indeed, other more interesting mechanisms beyond cis-mutations have emerged, including changes in the concentrations of RNA-binding regulatory proteins and other processing factors in, for example cancer, and mutations that affect the function of not only regulatory proteins but also components of the core splicing machinery, which is seen in various cancers as well as several neurodegenerative diseases. The proteins involved function in a variety of aspects of gene expression, including splicing and polyadenylation/ 3’ end formation of mRNA precursors. Although previous meetings have touched on these topics, this will be the first to focus exclusively on links between mRNA processing and human disease. The meeting will bring together two groups that only infrequently overlap: scientists/physicians whose primary interests center on disease but who have become interested in RNA processing as a result, and scientists who study basic mechanisms of RNA processing and gene expression that have proven to be relevant to disease.

Session Topics:

  • mRNA Splicing and Links to Disease
  • RNPs and Disease
  • MDS, Leukemia and Splicing
  • RNA-Based Therapeutic Approaches
  • Splicing and ALS
  • Further Links between RNA Processing and Disease

Deadlin­es:

  • Scholarship & Discounted Abstract: November 2, 2016
  • Late-Breaking Abstract: December 6, 2016
    (for plenary short talk or workshop presentation consideration)
  • Discounted Registration: January 10, 2017

(Through this date, you can still submit an abstract via our website for poster presentation and publication in our mobile app.)

For more information and to register, please visit the meeting website:
http://www.keystonesymposia.org/17C3

EMBL Course: Analysis and Integration of Transcriptome and Proteome Data

Benes, R. Calogero, J. Krijgsveld, L. Martens

Systems biology is a still expanding field of research aiming to understand at the molecular level how cells, tissues and organism operate in their biological context. Among the key technologies driving this forward are next-generation sequencing and proteomics, as they provide powerful means to determine globally expression levels of genes and proteins. Both fields have matured to a degree that they have now become accessible to researchers in many areas of biology.

Audience

This course is targeted at biologists and biochemists who are (or starting to be) involved in both next-generation sequencing and mass spectrometry-based proteomics, but who are not experts in these fields.

http://www.embl.de/training/events/2017/PRO17-01/index.html

The 4th Annual Symposium on RNA Science and Its Applications

*The RNA Institute, University at Albany Event*, https://www.rna.albany.edu/4th-annual-rna-symposium-rna-science-applications/

The 4th Annual Symposium on RNA Science and Its Applications is a full day of scientific presentations with a poster session and awards on Friday, March 17, 2017.

Additionally, The RNA Institute is providing 3 concurrent hands-on workshops on March 16, 2017 where participants can analyze their own samples! (NOTE:  Epitranscriptome workshop begins at 4pm on March 15, 2017).
Keynote Speakers & Session Topics:
Session 1:
mRNA Therapeutics: Processing and Targeting
Keynote:  Melissa J. Moore
Chair:  Eric Sontheimer

Session 2:  RNA Trafficking, Signaling, and Imaging
Keynote:  Maria Barna, PhD
Chair:  Tom Gingeras

Session 3:  lncRNAs and Therapeutic Applications
Keynote:  Jeanne B. Lawrence

Session 4:  RNA Structure Informs Function
Keynote:  Tom Steitz
Chair:  Marlene Belfort

Workshop Topics:
Epitranscriptome analysis of RNA modifications at attomole level
, presented by Dr. Maria Basanta-Sanchez, instructs participants how to prepare RNA samples for identifying RNA modifications using liquid chromatography and mass spectrometry (LCMS). In addition participants will learn how to operate LCMS instrumentation for RNA modification quantification and how to process the data for analysis.  You are welcome to bring your own sample for analysis.  Contact Dr. Basanta-Sanchez for sample requirements.

microRNA detection using nanoswitch technology, presented by Dr. Kenneth Halvorsen, instructs participants how to detect microRNA using DNA nanoswitches and standard gel electrophoresis. Participants will learn how to prepare, purify, and use the nanoswitches, and how to analyze the data. Please contact Dr. Halvorsen directly if you are interested in using your own microRNA sample in the workshop.

RNA Dynamics: Structural Modeling Through Simulation Workshop, presented by Drs. Paul Whitford, Alan Chen, and Sri Ranganathan

Keystone Symposia: RNA-Based Approaches in Cardiovascular Diseases

Scientific Organizers:
Thomas Thum, Medical School Hannover, Germany and
Roger J. Hajjar, Mount Sinai School of Medicine, USA

joint with the meeting on

Molecular Mechanisms of Heart Development

Scientific Organizers:
Benoit G. Bruneau, Gladstone Institute of Cardiovascular Disease, USA
Brian L. Black, University of California, San Francisco, USA
Margaret E. Buckingham, Institut Pasteur, France

Submit an abstract and register for these Keystone Symposia conferences that will take place March 2630, 2017 at Keystone Conference Center, Keystone, Colorado, USA.

Cardiac diseases are the leading cause of death worldwide. RNA-based mechanisms and therapeutic approaches are emerging fields in cardiovascular science. This meeting will present and discuss latest developments using both coding RNA and noncoding RNA (such as microRNAs, long noncoding RNAs and circular RNAs) -based approaches to better understand and develop new therapeutic strategies for cardiac diseases. Attendees will benefit from workshops, specific sessions and industrial perspectives covering everything from basic science to clinical translation employing RNA therapeutics in cardiovascular medicine.

Deadlin­es:

  • Scholarship & Discounted Abstract: November 30, 2016
  • Late-Breaking Abstract: January 11, 2017
    (for plenary short talk or workshop presentation consideration)
  • Discounted Registration: January 26, 2017

(Through this date, you can still submit an abstract via our website for poster presentation and publication in our mobile app.)

For more information and to register, please visit the meeting websites:
http://www.keystonesymposia.org/17X8 | http://www.keystonesymposia.org/17X7

Registered attendees of one meeting in a joint pair may participate in sessions of the other, pending space availability.

EMBL Course: Whole Transcriptome Data Analysis

Benes, R. Calogero

The course participants will learn how to use BioConductor software and Illumina BaseSpace Cloud apps. In the first three days, the course covers various topics using the oneChannelGUI graphical interface. The last day is dedicated to providing the basics to move from the use of the graphical environment to command line. The basics of R scripting will be described and some of the workflows used in the first three days will be dissected and executed using command line approach. All computers for hands-on exercises will be provided along with demo data sets.

Audience

This course was developed for biologists as the intended audience, particularly for those already with basic knowledge of massively parallel sequencing (MPS). However, R-coding skills and deep knowledge of statistics are not necessary for attendance.

http://www.embl.de/training/events/2017/DAT17-01/index.html

EMBL Course: Digital PCR

Bizouarn, D. Dewolf, J. Dreyer-Lamm

Real-time PCR has been adopted as the gold standard for nucleic acid target quantification in genomics research and is increasingly used for clinical analysis. However, there are some applications, such as precise measurement of copy number variation, low-abundance sequence detection, detection of rare mutations, including distinguishing rare sequences in tumours, and low-level gene expression analysis, where real-time PCR shows limitations. Digital PCR overcomes those limitations by enabling researchers to directly quantify nucleic acids, without the need for a standard curve, and provides higher precision than real-time PCR.

http://www.embl.de/training/events/2017/PCR17-01/index.html

EMBL Course: Whole Transcriptome Data Analysis

Benes, R. Calogero

The course participants will use BioConductor software and Illumina BaseSpace Cloud apps. R-coding skills and deep knowledge of statistics are not necessary for attendance because most analyses will be performed with OneChannelGUI (a graphical interface to a series of BioConductor tools, which enables handling microarray data analysis as well as RNA-seq data without requiring programming skills). Computers for hands-on exercises will be provided along with demo data sets. Upon request, participants could bring along their own data to analyse.

Audience

This course was developed for biologists as the intended audience. Basic knowledge of massively parallel sequencing (MPS) is desirable.

http://www.embl.de/training/events/2017/DAT17-02/index.html