San Diego, CA – View General Invitation Here

The workshop is intended to provide an overview of recent insights about the fate of mRNAs in the cytoplasm, in particular the events promoting or preventing mRNA translation in a certain cell location and at a certain time, determining proteome changes and the phenotype of cells, and leading when altered to disease.

The workshop is an arena for the interaction of young investigators with experienced scientists. Plenary talks will be focused on broad topics; extensive discussions, poster sessions and meetings will promote contacts of postdocs and PhD students with the leading experts of the field.

The programme will cover:

• mRNA trafficking;
• mRNA translational control;
• RNA-protein structures;
• RNA metabolism and diseases;
• Systems Biology of RNA.

Official web page:

http://events.unitn.it/en/mrnafate2012

Keynote lecture: Nahum  Sonenberg

Confirmed Speakers:

Yoav Arava (Haifa, Israel), Claudia Bagni (Leuven, Belgium), Stefano Biffo (Milan, Italy), Elena Conti (Munich, Germany), Witold Filipowicz (Basel, Switzerland), André P. Gerber (Zurich, Switzerland), Roberto Gherzi (Genova, Italy), Robert Gilbert (Oxford, UK), Myriam Gorospe (Baltimore, USA), Stefan Hüttelmaier (Halle, Germany), Jack Keene (Durham, USA), Michael Kiebler (Vienna, Austria), Fabrizio Loreni (Roma, Italy), Raul Mendez (Barcelona, Spain), Kiyoshi Nagai (Cambridge,UK), Dierk Niessing (Munich, Germany), Davide Ruggero (San Francisco, USA), Robert Schneider (New York, USA), Matthias Selbach (Berlin, Germany), Nahum Sonenberg (Montreal, Canada), Jacqueline Trotter (Mainz, Germany), Gabriele Varani (Seattle, USA), Anne E. Willis (Leicester, UK)

Official Announcement Page

Meeting background

Our understanding of the role played by RNA molecules in the control of gene expression has evolved rapidly within recent years. Novel regulatory RNA elements have been identified in both eukaryota and prokaryota, including siRNAs, piRNAs, miRNAs, sRNAs, CRISPRs, riboswitches and RNA thermometers. These elements can fine tune mRNA metabolism according to the output of complex signalling networks or may provide simple on/off switches that respond to macroscopic changes in the cellular environment (e.g. temperature). They vary in size, in structure and in functional mechanism.

Although important differences exist in the RNA regulation of prokaryota and eukaryota, parallels are starting to emerge. The aim of this meeting is to provide a forum to discuss both parallels and differences, achieving a better understanding of the role of RNA in regulating gene expression.

The speakers of this Harden conference will discuss their work on RNA-based regulation in different organisms. Scientists in the audience, also working on a diverse range of systems, will take on the discussion in two poster sessions and informal events.

Before the genetic information stored in the DNA can be used to direct cell growth and metabolism it has to be transferred into RNA.  Messenger RNAs (mRNAs) are key components in the transmission of genetic information in all life forms – from viruses to complex mammalian organisms. Exciting recent findings have revealed a remarkable degree of complexity in the lives of mRNAs and the field is rapidly developing.

The EMBO | EMBL Symposium “Complex Life of mRNA” will bring leaders in the mRNA field together with post-docs and students, with the aim of disseminating and discussing the most recent results. The programme includes sessions on:

• transcription;
• mRNA processing;
• export and localization;
• mRNA surveillance and decay;
• translation and the control of mRNA expression by microRNAs.

D. Tollervey, J. Steitz, N. Sonenberg, A. Ephrussi

EMBL Heidelberg, Germany

Sunday 7 October – Wednesday 10 October 2012

Registration and payment deadline is 23 August 2012.

Abstract submission deadline is 2 August 2012.

Official Web Page

View Official Announcement

Join us October 28-31 in Boston, Massachusetts for the

8th Annual Meeting of the Oligonucleotide Therapeutics Society!

Join leading experts in the field during this three day meeting, which will feature the latest developments from various oligonucleotide-based disciplines including antisense, siRNA, immunomodulatory, aptamers and micro/non-coding RNA research.

Organizing Chair

Scientific Program Committee

Keynote Session

Topics will include all areas of Oligonucleotide Therapeutics covering: