The Deaconescu Lab at Brown University

The Deaconescu Lab at Brown University is seeking a motivated and energetic and postdoctoral. The laboratory’s interest is the interplay between DNA repair and other cellular processes including transcription and chromatin remodeling, and is focused on elucidating the function and mechanochemistry of nucleic acid-based motors using a combination of biochemical, biophysical and structural techniques. (e.g. X-Ray crystallography, small-angle X-ray scattering, transmission electron microscopy). For examples of work, please see Kutter et al. JMB (2016), Deaconescu et al., PNAS (2012), Szyk et al, Cell (2014), Szyk et al., NSMB (2012) and Deaconescu et al., TIBS (2013). A successful candidate should have the following qualifications: a Ph.D. in the field of Molecular Biology, Cell Biology, Biochemistry or related field; an established track-record of publications in peer-reviewed journals; solid experience in the biochemistry of nucleic acind-binding proteins, their purification from E.coli/yeast expression systems as well as their characterization using functional studies such as by isothermal titration calorimetry and fluorescence. Prior knowledge of crystallography is desired. Must be highly motivated and work independently as well as in a team. Excellent spoken and written English are required. New Ph.D. graduates are encouraged to apply. Salary and starting date are negotiable.

Interested candidates should send a CV, one page research experience summary and contact information for three references to alexandra_deaconescu@nullbrown.edu. Salary and starting date are negotiable. Please write Postdoctoral Candidate in the e-mail subject header

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