RNA PROCESSING DURING DEVELOPMENT AND DISEASE

“RNA PROCESSING DURING DEVELOPMENT AND DISEASE”

A post-doctoral position is available in the Department of Biochemistry
at the University of Illinois at Urbana-Champaign starting January 2013 to study the
mechanisms and role of RNA processing in mammalian liver development and
disease. Research in the laboratory will focus on investigating both the alternative splicing and alternative polyadenylation networks in liver. We will utilize inter-disciplinaryapproaches that combine mouse genetics, biochemistry, and genome-wide analyses (e.g. RNA-seq, CLIP-Seq and splicing-sensitive microarrays) to understand the mechanisms through which alternative splicing drives critical developmental transitions in liver. We also intend to determine how RNA processing impacts metabolic functions of the liver and how crosstalk between microRNAs and RNA binding proteins integrate with coordinated gene expression changes that propel normal liver development or disease.

Highly motivated candidates with a strong interest in RNA biology, other aspects
of gene regulation, and/or developmental biology are encouraged to apply. Experience
with mouse genetics or mammalian cell-based approaches is a plus but not required.
Interested applicants should respond electronically with curriculum vitae, statement of
career interests, and contact information for three references to Auinash Kalsotra, PhD at kalsotra@nullillinois.edu and kalsotra33@nullgmail.com.

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